Rabbit TMED10 / TMP21 Polyclonal Antibody | anti-TMED10 antibody

Rabbit Polyclonal to Human TMED10 / TMP21

Cat. Num. AAA50701

• Gene Names: TMED10; p23; TMP21; S31I125; Tmp-21-I; S31III125; P24(DELTA)
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, Immunohistochemistry
• Purity: Purified
• Synonyms: TMED10 / TMP21, Antibody; Rabbit Polyclonal to Human TMED10 / TMP21; Anti-TMED10 / TMP21 Antibody (C-Terminus) IHC-plus; TMED10; S31III125; Transmembrane protein Tmp21; p23; p24 family protein delta-1; p24(DELTA); p24delta; p24delta1; S31I125; Tmp-21-I; TMP21; Human TMED10; anti-TMED10 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Specificity: 19 amino acid peptide from near the carboxy terminus of human TMP21.
• Purity/Purification: Purified
• Form/Format: PBS, 0.02% sodium azide.
• Concentration: 1 mg/ml (varies by lot)
• Sequence Length: 219

• Applicable Applications for anti-TMED10 antibody: WB (Western Blot), IHC (Immunohistochemistry)
• Target Species: Human
• Immunogen Description: Synthetic peptide from human TMED10 / TMP21.
• Immunogen Type: Synthetic peptide
• Immunogen: TMED10 / TMP21 antibody was raised against synthetic peptide from human TMED10 / TMP21.
• Antigen Modification: C-Terminus
• Preparation and Storage: Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.

WB (Western Blot)

(Western blot of TMP21 in Raji cell lysate with TMP21 antibody at (A) 0.5 and (B) 1 and (C) 2 ug/ml.)

IF (Immunofluorescence)

(Immunofluorescence of TMP21 in Human Brain cells with TMP21 antibody at 20 ug/ml.)

IHC (Immunohiostchemistry)

(Anti-TMED10 / TMP21 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3 ug/ml.)

IHC (Immunohistochemistry)

(Anti-TMED10 / TMP21 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3 ug/ml.)

Related Product Information for anti-TMED10 antibody

TMP 21 is a integral membrane protein that is localized in microsomal membranes, zymogen granule membrane and the plasma membrane. It is ubiquitously expressed and is involved in vesicular targeting and protein transport. Recent studies have shown that TMP21 is a component of presinilin complexes and differentially regulates gamma-secretase cleavage of the amyloid precursor protein, without affecting epsilon-secretase activity.

NCBI and Uniprot Product Information

• NCBI GI #: 98986464
• NCBI GeneID: 10972
• NCBI Accession #: NP_006818.3
• NCBI GenBank Nucleotide #: NM_006827.5
• UniProt Accession #: P49755; Q15602; Q16536; Q86TC2; Q86TS5; B2R605
• Molecular Weight: 24,976 Da
• NCBI Official Full Name: transmembrane emp24 domain-containing protein 10
• NCBI Official Synonym Full Names: transmembrane emp24-like trafficking protein 10 (yeast)
• NCBI Official Symbol: TMED10
• NCBI Official Synonym Symbols: p23; TMP21; S31I125; Tmp-21-I; S31III125; P24(DELTA)
• NCBI Protein Information: transmembrane emp24 domain-containing protein 10; p24delta; p24delta1; p24 family protein delta-1; transmembrane protein Tmp21; 21 kDa transmembrane trafficking protein; 21 kDa transmembrane-trafficking protein
• UniProt Protein Name: Transmembrane emp24 domain-containing protein 10
• UniProt Gene Name: TMED10
• UniProt Synonym Gene Names: TMP21; S31I125; p24delta1
• UniProt Entry Name: TMEDA_HUMAN