FCM/FACS (Flow Cytometry)
(TPSAB1 Antibody (Center) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Rabbit anti-Human TPSAB1 Polyclonal Antibody | anti-TPSAB1 antibody
TPSAB1 Antibody (Center)
Gene Names
TPSAB1; TPS1; TPS2; TPSB1
Reactivity
Human
Applications
Flow Cytometry, Functional Assay, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
TPSAB1, Antibody; TPSAB1 Antibody (Center); Tryptase alpha/beta-1; Tryptase-1; Tryptase I; Tryptase alpha-1; TPSAB1; TPS1; TPS2; TPSB1; anti-TPSAB1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This TPSAB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 61-87 amino acids from the Central region of human TPSAB1.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
61-87
Sequence Length
266
Applicable Applications for anti-TPSAB1 antibody
FCM/FACS (Flow Cytometry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
FCM/FACS (Flow Cytometry)
(TPSAB1 Antibody (Center) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
FCM/FACS (Flow Cytometry)
(TPSAB1 Antibody (Center) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
WB (Western Blot)
(TPSAB1 Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the TPSAB1 antibody detected the TPSAB1 protein (arrow).)
WB (Western Blot)
(TPSAB1 Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the TPSAB1 antibody detected the TPSAB1 protein (arrow).)
Related Product Information for anti-TPSAB1 antibody
Tryptases comprise a family of trypsin-like serine
proteases, the peptidase family S1. Tryptases are enzymatically
active only as heparin-stabilized tetramers, and they are resistant
to all known endogenous proteinase inhibitors. Several tryptase
genes are clustered on chromosome 16p13.3. These genes are
characterized by several distinct features. They have a highly
conserved 3' UTR and contain tandem repeat sequences at the 5'
flank and 3' UTR which are thought to play a role in regulation of
the mRNA stability. These genes have an intron immediately upstream
of the initiator Met codon, which separates the site of
transcription initiation from protein coding sequence. This feature
is characteristic of tryptases but is unusual in other genes. The
alleles of this gene exhibit an unusual amount of sequence
variation, such that the alleles were once thought to represent two
separate genes, alpha and beta 1. Beta tryptases appear to be the
main isoenzymes expressed in mast cells; whereas in basophils,
alpha tryptases predominate. Tryptases have been implicated as
mediators in the pathogenesis of asthma and other allergic and
inflammatory disorders.
proteases, the peptidase family S1. Tryptases are enzymatically
active only as heparin-stabilized tetramers, and they are resistant
to all known endogenous proteinase inhibitors. Several tryptase
genes are clustered on chromosome 16p13.3. These genes are
characterized by several distinct features. They have a highly
conserved 3' UTR and contain tandem repeat sequences at the 5'
flank and 3' UTR which are thought to play a role in regulation of
the mRNA stability. These genes have an intron immediately upstream
of the initiator Met codon, which separates the site of
transcription initiation from protein coding sequence. This feature
is characteristic of tryptases but is unusual in other genes. The
alleles of this gene exhibit an unusual amount of sequence
variation, such that the alleles were once thought to represent two
separate genes, alpha and beta 1. Beta tryptases appear to be the
main isoenzymes expressed in mast cells; whereas in basophils,
alpha tryptases predominate. Tryptases have been implicated as
mediators in the pathogenesis of asthma and other allergic and
inflammatory disorders.
Product Categories/Family for anti-TPSAB1 antibody
References
Trivedi, N.N., et al. J. Allergy Clin. Immunol. 124(5):1099-1105(2009)
Radhakrishnan, Y., et al. Biol. Reprod. 81(4):647-656(2009)
Schiemann, F., et al. J. Immunol. 183(4):2223-2231(2009)
Radhakrishnan, Y., et al. Biol. Reprod. 81(4):647-656(2009)
Schiemann, F., et al. J. Immunol. 183(4):2223-2231(2009)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
30515
NCBI Official Full Name
tryptase alpha/beta-1
NCBI Official Synonym Full Names
tryptase alpha/beta 1
NCBI Official Symbol
TPSAB1
NCBI Official Synonym Symbols
TPS1; TPS2; TPSB1
NCBI Protein Information
tryptase alpha/beta-1
UniProt Protein Name
Tryptase alpha/beta-1
UniProt Gene Name
TPSAB1
UniProt Synonym Gene Names
TPS1; TPS2; TPSB1; Tryptase-1
UniProt Entry Name
TRYB1_HUMAN
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Product Notes
The TPSAB1 tpsab1 (Catalog #AAA290246) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 61-87. The TPSAB1 Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TPSAB1 can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the TPSAB1 tpsab1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TPSAB1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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