Rabbit TRAF2 Polyclonal Antibody | anti-TRAF2 antibody

TRAF2 Antibody

Cat. Num. AAA39581

• Gene Names: TRAF2; TRAP; TRAP3; MGC:45012
• Reactivity: Human, Mouse, Rat
• Applications: Immunoprecipitation, Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
• Purity: TRAF2 Antibody is affinity chromatography purified via peptide column.
• Synonyms: TRAF2, Antibody; TRAF2 Antibody; TRAF2; TRAP; TRAP3; MGC:45012; TNF receptor-associated factor 2; E3 ubiquitin-protein ligase TRAF2; anti-TRAF2 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: TRAF2 Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 476

• Applicable Applications for anti-TRAF2 antibody: IP (Immunoprecipitation), IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: TRAF2 antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human TRAF2.
• Buffer: TRAF2 Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: TRAF2 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of TRAF2 in Hela cells with TRAF2 antibody at 20 μg/mL.Green: TRAF2 Antibody (3663)Blue: DAPI staining)

IF (Immunofluorescence)

(Immunofluorescence of TRAF2 in human liver tissue with TRAF2 antibody at 20 μg/mL.)

IHC (Immunohiostchemistry)

(Immunohistochemistry of TRAF2 in human liver tissue with TRAF2 antibody at 2.5 μg/mL.)

WB (Western Blot)

(Western blot analysis of TRAF2 in human liver tissue lysate with TRAF2 antibody at (A) 0.5, (B) 1 and (C) 2 μg/mL.)

Related Product Information for anti-TRAF2 antibody

TRAF2 Antibody: Tumor necrosis factor (TNF) receptor associated factors (TRAFs) were initially discovered as adaptor proteins that link the TNF receptor superfamily to signaling pathways and are thus important regulators of cell death and cellular response to stress. TRAF proteins share a homology region that allows them to bind to cell receptors and other TRAF proteins, causing the activation of different signal cascades depending on the TRAFs involved. For example, TRAF2 and TRAF3 directly bind to the CD40, a NF receptor superfamily member involved in inducing B cell immunity, and are critical for NF-κB activation in mouse B lymphocytes. TRAF2 along with TRAF6 has also been shown to be required for CD40 signaling in nonhemopoietic cells. TRAF2 also interacts with the TRFR superfamily member lymphotoxin-beta receptor (LTbetaR) in association with TRAF3 and the apoptosis inhibitors cIAP1 and Smac.

NCBI and Uniprot Product Information

• NCBI GI #: 55959980
• NCBI GeneID: 7186
• UniProt Accession #: Q12933; Q7Z337; Q96NT2; A8K107; B4DPJ7
• Molecular Weight: 53,055 Da
• NCBI Official Synonym Full Names: TNF receptor-associated factor 2
• NCBI Official Symbol: TRAF2
• NCBI Official Synonym Symbols: TRAP; TRAP3; MGC:45012
• NCBI Protein Information: TNF receptor-associated factor 2
• UniProt Protein Name: TNF receptor-associated factor 2
• UniProt Gene Name: TRAF2
• UniProt Synonym Gene Names: TRAP3
• UniProt Entry Name: TRAF2_HUMAN