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IHC (Immunohistochemistry)
(Immunohistochemistry of TRPV4 in human kidney tissue with TRPV4 antibody at 2 μg/ml.)
Rabbit anti-Human TRPV4 Polyclonal Antibody | anti-TRPV4 antibody
TRPV4 Antibody
Gene Names
TRPV4; SMAL; VRL2; CMT2C; SPSMA; TRP12; VROAC; HMSN2C; OTRPC4; SSQTL1
Reactivity
Human
Applications
Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
Purity
TRPV4 antibody is affinity chromatography purified via peptide column.
Synonyms
TRPV4, Antibody; TRPV4 Antibody; TRPV4; SMAL; VRL2; CMT2C; SPSMA; TRP12; VROAC; HMSN2C; OTRPC4; SSQTL1; Transient receptor potential cation channel subfamily V member 4; Osm-9-like TRP channel 4; TrpV4; transient receptor potential cation channel, subfamily V, member 4; anti-TRPV4 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
TRPV4 antibody is human specific. At least six isoforms of TRPV4 are known to exist. This antibody is predicted to not cross-react with other TRP protein family members.
Purity/Purification
TRPV4 antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
871
Applicable Applications for anti-TRPV4 antibody
IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
TRPV4 antibody was raised against an 18 amino acid peptide near the center of human TRPV4.
Buffer
TRPV4 antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
TRPV4 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year.
IHC (Immunohistochemistry)
(Immunohistochemistry of TRPV4 in human kidney tissue with TRPV4 antibody at 2 μg/ml.)
IHC (Immunohistochemistry)
(Immunohistochemistry of TRPV4 in human kidney tissue with TRPV4 antibody at 2 μg/ml.)
IF (Immunofluorescence)
(Immunofluorescence of TRPV4 in human kidney tissue with TRPV4 antibody at 5 μg/ml.Red: TRPV4 Antibody (7695)Blue: DAPI staining)
IF (Immunofluorescence)
(Immunofluorescence of TRPV4 in human kidney tissue with TRPV4 antibody at 5 μg/ml.Red: TRPV4 Antibody (7695)Blue: DAPI staining)
IF (Immunofluorescence)
(Immunofluorescence of TRPV4 in human lung tissue with TRPV4 antibody at 20 μg/mL.)
IF (Immunofluorescence)
(Immunofluorescence of TRPV4 in human lung tissue with TRPV4 antibody at 20 μg/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of TRPV4 in human lung tissue with TRPV4 antibody at 5 μg/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of TRPV4 in human lung tissue with TRPV4 antibody at 5 μg/mL.)
WB (Western Blot)
(Western blot analysis of TRPV4 in (A) human testis tissue and (B) SK-N-SH cell lysate with TRPV4 antibody at 1 μg/mL.)
WB (Western Blot)
(Western blot analysis of TRPV4 in (A) human testis tissue and (B) SK-N-SH cell lysate with TRPV4 antibody at 1 μg/mL.)
Related Product Information for anti-TRPV4 antibody
The transient receptor potential (TRP) protein family consists of a diverse group of cation channels functioning in a variety of homeostatic and regulatory pathways. Four subfamilies exist, based on channel domain homology: C type (canonical), V type (vanilloid receptor related), M type (melastatin related) and P type (PKD) (1). TRPV4, belongs to the V type subfamily and plays a role in systemic osmoregulation (2,3). TRPV4 is a calcium channel multi-pass membrane protein activated by various stimuli, including thermal stress, fatty acid metabolites and hypotonicity (3). TRPV4 is highly expressed in lung and kidney and widely expressed in brain. It plays an important role in regulating neural excitability (4).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Predicted: 96 kDa
Observed: 110 kDa
Observed: 110 kDa
NCBI Official Full Name
transient receptor potential cation channel subfamily V member 4 isoform a
NCBI Official Synonym Full Names
transient receptor potential cation channel, subfamily V, member 4
NCBI Official Symbol
TRPV4
NCBI Official Synonym Symbols
SMAL; VRL2; CMT2C; SPSMA; TRP12; VROAC; HMSN2C; OTRPC4; SSQTL1
NCBI Protein Information
transient receptor potential cation channel subfamily V member 4; osm-9-like TRP channel 4; vanilloid receptor-like channel 2; transient receptor potential protein 12; OSM9-like transient receptor potential channel 4; osmosensitive transient receptor potential channel 4; vanilloid receptor-related osmotically activated channel
UniProt Protein Name
Transient receptor potential cation channel subfamily V member 4
UniProt Gene Name
TRPV4
UniProt Synonym Gene Names
VRL2; VROAC; TrpV4; OTRPC4; TRP12; VRL-2; VR-OAC
UniProt Entry Name
TRPV4_HUMAN
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Product Notes
The TRPV4 trpv4 (Catalog #AAA40739) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TRPV4 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TRPV4 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the TRPV4 trpv4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TRPV4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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