IHC (Immunohiostchemistry)
(Anti-uPA Receptor antibody, AAA45039, IHC(P)IHC(P): Human Mammary Cancer Tissue)
Rabbit anti-Human uPA Receptor Polyclonal Antibody | anti-PLAUR antibody
Anti-uPA Receptor antibody
Gene Names
PLAUR; CD87; UPAR; URKR; U-PAR
Reactivity
Human
Applications
Immunohistochemistry, Western Blot
Purity
Immunogen affinity purified.
Synonyms
uPA Receptor, Antibody; Anti-uPA Receptor antibody; Urokinase plasminogen activator surface receptor(U-PAR/uPAR); plasminogen activator, urokinase receptor; CD 87 antibody; CD87 antibody; CD87 antigen antibody; MO 3 antibody; MO3 antibody; Monocyte activation antigen Mo3 antibody; Plasminogen activator urokinase receptor antibody; PLAUR antibody; U PAR antibody; u plasminogen activator receptor antibody; U-PAR antibody; UPA receptor antibody; UPAR antibody; UPAR_HUMAN antibody; Urinary plasminogen activator receptor antibody; URKR antibody; Urokinase plasminogen activator receptor antibody; Urokinase plasminogen activator surface receptor antibody; anti-PLAUR antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Sequence Length
335
Applicable Applications for anti-PLAUR antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human uPA Receptor (293-304aa CNHPDLDVQYRS).
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
IHC (Immunohiostchemistry)
(Anti-uPA Receptor antibody, AAA45039, IHC(P)IHC(P): Human Mammary Cancer Tissue)
IHC (Immunohiostchemistry)
(Anti-uPA Receptor antibody, AAA45039, IHC(P)IHC(P): Human Mammary Cancer Tissue)
WB (Western Blot)
(Anti-uPA Receptor antibody, AAA45039, Western blottingLane 1: MCF-7 Cell LysateLane 2: HELA Cell LysateLane 3: RAJI Cell LysateLane 4: SMMC Cell Lysate)
WB (Western Blot)
(Anti-uPA Receptor antibody, AAA45039, Western blottingLane 1: MCF-7 Cell LysateLane 2: HELA Cell LysateLane 3: RAJI Cell LysateLane 4: SMMC Cell Lysate)
Related Product Information for anti-PLAUR antibody
Description: Rabbit IgG polyclonal antibody for Urokinase plasminogen activator surface receptor(PLAUR) detection. Tested with WB, IHC-P in Human.
Background: PLAUR(PLASMINOGEN ACTIVATOR RECEPTOR, UROKINASE-TYPE), also known as UPAR or CD87, is multidomain glycoprotein tethered to the cell membrane with a glycosylphosphotidylinositol(GPI) anchor. PLAUR consists of three different domains of the Ly-6/uPAR/alpha-neurotoxin family. PLAUR is originally identified as a saturable binding site for urokinase on the cell surface. And the gene plays an important role in many normal as well as pathologic processes. The PLAUR gene is localized to 19q13.31. PLAUR is a part of the plasminogen activation system, which in the healthy body is involved in tissue reorganization events such as mammary gland involution and wound healing. PLAUR binds urokinase and thus restricts plasminogen activation to the immediate vicinity of the cell membrane. Thus it seems to be an important player in the regulation of this process. In human coronary artery vascular smooth muscle cells, UPA stimulates cell migration via a UPAR signaling complex containing TYK2 and phosphatidylinositol 3-kinase.
Background: PLAUR(PLASMINOGEN ACTIVATOR RECEPTOR, UROKINASE-TYPE), also known as UPAR or CD87, is multidomain glycoprotein tethered to the cell membrane with a glycosylphosphotidylinositol(GPI) anchor. PLAUR consists of three different domains of the Ly-6/uPAR/alpha-neurotoxin family. PLAUR is originally identified as a saturable binding site for urokinase on the cell surface. And the gene plays an important role in many normal as well as pathologic processes. The PLAUR gene is localized to 19q13.31. PLAUR is a part of the plasminogen activation system, which in the healthy body is involved in tissue reorganization events such as mammary gland involution and wound healing. PLAUR binds urokinase and thus restricts plasminogen activation to the immediate vicinity of the cell membrane. Thus it seems to be an important player in the regulation of this process. In human coronary artery vascular smooth muscle cells, UPA stimulates cell migration via a UPAR signaling complex containing TYK2 and phosphatidylinositol 3-kinase.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
32,016 Da
NCBI Official Full Name
Urokinase plasminogen activator surface receptor
NCBI Official Synonym Full Names
plasminogen activator, urokinase receptor
NCBI Official Symbol
PLAUR
NCBI Official Synonym Symbols
CD87; UPAR; URKR; U-PAR
NCBI Protein Information
urokinase plasminogen activator surface receptor; monocyte activation antigen Mo3; u-plasminogen activator receptor form 2; urokinase-type plasminogen activator (uPA) receptor
UniProt Protein Name
Urokinase plasminogen activator surface receptor
UniProt Gene Name
PLAUR
UniProt Synonym Gene Names
MO3; UPAR; U-PAR; uPAR
UniProt Entry Name
UPAR_HUMAN
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Product Notes
The PLAUR plaur (Catalog #AAA45039) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-uPA Receptor antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's uPA Receptor can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the PLAUR plaur for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "uPA Receptor, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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