Rabbit UPK1B Polyclonal Antibody | anti-UPK1B antibody

UPK1B Antibody

Cat. Num. AAA39950

• Gene Names: UPK1B; UPIB; UPK1; TSPAN20
• Reactivity: Human, Mouse, Rat
• Applications: Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
• Purity: UPK1B Antibody is affinity chromatography purified via peptide column.
• Synonyms: UPK1B, Antibody; UPK1B Antibody; UPK1B; UPIB; UPK1; TSPAN20; Uroplakin-1b; Tetraspanin-20; UP1b; uroplakin 1B; anti-UPK1B antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: At least two isoforms of UPK1B are known to exist; this antibody will recognize both isoforms. UPK1B antibody is predicted to not cross-react with other tetraspanin protein family members.
• Purity/Purification: UPK1B Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 260

• Applicable Applications for anti-UPK1B antibody: IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: UPK1B antibody was raised against a 17 amino acid synthetic peptide near the center of human UPK1B.
• Buffer: UPK1B Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: UPK1B antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of UPK1B in human bladder muscle tissue with UPK1B antibody at 20 μg/mL.)

IHC (Immunohiostchemistry)

(Immunohistochemistry of UPK1B in human bladder tissue with UPK1B antibody at 5 μg/mL.)

WB (Western Blot)

(Western blot analysis of UPK1B in human kidney tissue lysate with UPK1B antibody at 1 μg/mL in the (A) absence and (B) presence of blocking peptide.)

Related Product Information for anti-UPK1B antibody

UPK1B Antibody: Uroplakin-1B (UPK1B) is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. UPK1B is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins and may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions.

NCBI and Uniprot Product Information

• NCBI GI #: 49619237
• NCBI GeneID: 7348
• NCBI Accession #: NP_008883
• NCBI GenBank Nucleotide #: NM_006952.3
• UniProt Accession #: O75841; O60753; Q9UIM2; Q9UNX6
• Molecular Weight: 29,643 Da
• NCBI Official Full Name: uroplakin-1b
• NCBI Official Synonym Full Names: uroplakin 1B
• NCBI Official Symbol: UPK1B
• NCBI Official Synonym Symbols: UPIB; UPK1; TSPAN20
• NCBI Protein Information: uroplakin-1b; UP1b; tspan-20; tetraspan; uroplakin Ib; tetraspanin-20
• UniProt Protein Name: Uroplakin-1b
• UniProt Gene Name: UPK1B
• UniProt Synonym Gene Names: TSPAN20; UP1b; Tspan-20; UPIb
• UniProt Entry Name: UPK1B_HUMAN