Rabbit VITRN Polyclonal Antibody | anti-VIT antibody

VITRN Antibody (C-term)

Cat. Num. AAA286055

• Reactivity: Human; Predicted Reactivity: Bovine, Mouse
• Applications: Flow Cytometry, Functional Assay, Immunohistochemistry, ELISA, Western Blot
• Purity: This antibody is purified through a protein A column, followed by peptide affinity purification.
• Synonyms: VITRN, Antibody; VITRN Antibody (C-term); Vitrin; VIT; anti-VIT antibody

• Host: Rabbit
• Reactivity: Human; Predicted Reactivity: Bovine, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: This VITRN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 567-595 amino acids from the C-terminal region of human VITRN.
• Purity/Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
• Form/Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
• Sequence Positions: 567-595
• Sequence Length: 678

• Applicable Applications for anti-VIT antibody: FCM/FACS (Flow Cytometry), IHC (Immunohistochemistry), ELISA, WB (Western Blot)
• Function: Promotes matrix assembly and cell adhesiveness. Plays a role in spinal cord formation by regulating the proliferation and differentiation of neural stem cells.
• Cellular Location: Secreted, extracellular space, extracellular matrix
• Preparation and Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

FCM/FACS (Flow Cytometry)

(VITRN Antibody (C-term) flow cytometric analysis of U251 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

IHC (Immunohiostchemistry)

(VITRN antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the VITRN antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

WB (Western Blot)

(VITRN Antibody (C-term) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the VITRN antibody detected the VITRN protein (arrow).)

Related Product Information for anti-VIT antibody

Promotes matrix assembly and cell adhesiveness (By similarity).

Product Categories/Family for anti-VIT antibody

Signal Transduction

References

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
Tomarev, S.I., et al. Invest. Ophthalmol. Vis. Sci. 44(6):2588-2596(2003)
Whittaker, C.A., et al. Mol. Biol. Cell 13(10):3369-3387(2002)
Mayne, R., et al. Biochem. Soc. Trans. 27(6):832-835(1999)

NCBI and Uniprot Product Information

• NCBI GI #: 295789104
• NCBI GeneID: 5212
• NCBI Accession #: NP_001171440.1; NP_001171441.1; NP_001171442.1; NP_001171443.1; NP_444506.2
• NCBI GenBank Nucleotide #: NM_001177969.1
• UniProt Accession #: Q6UXI7; Q6P7T3; Q96DM8; Q96DT1; Q9UDN0; A1A526; A6NKI9; A8K7Y4; E9PF47
• Molecular Weight: 73930
• NCBI Official Full Name: vitrin isoform 2
• NCBI Official Synonym Full Names: vitrin
• NCBI Official Symbol: VIT
• NCBI Protein Information: vitrin
• UniProt Protein Name: Vitrin
• UniProt Gene Name: VIT
• UniProt Entry Name: VITRN_HUMAN