IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using at dilution 1/60.)
Rabbit anti-Human XBP1 Polyclonal Antibody | anti-XBP1 antibody
XBP1 Antibody
Gene Names
XBP1; XBP2; TREB5; XBP-1; TREB-5
Reactivity
Human
Applications
Immunohistochemistry
Purity
Antigen affinity purification.
Synonyms
XBP1, Antibody; XBP1 Antibody; XBP2; TREB5; XBP-1; anti-XBP1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total XBP1 protein.
Purity/Purification
Antigen affinity purification.
Form/Format
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Concentration
1.9 mg/ml (varies by lot)
Sequence Length
376
Applicable Applications for anti-XBP1 antibody
IHC (Immunohistochemistry)
Immunogen Type
Recombinant Protein
Immunogen Description
Full length fusion protein
Target Name
XBP1
Preparation and Storage
Store at -20 degree C
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using at dilution 1/60.)
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using at dilution 1/60.)
IHC (Immunohistochemistry)
(Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue using at dilution 1/60.)
IHC (Immunohistochemistry)
(Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue using at dilution 1/60.)
Related Product Information for anti-XBP1 antibody
This gene encodes a transcription factor that regulates MHC class II genes by binding to a promoter element referred to as an X box. This gene product is a bZIP protein, which was also identified as a cellular transcription factor that binds to an enhancer in the promoter of the T cell leukemia virus type 1 promoter. It may increase expression of viral proteins by acting as the DNA binding partner of a viral transactivator. It has been found that upon accumulation of unfolded proteins in the endoplasmic reticulum (ER), the mRNA of this gene is processed to an active form by an unconventional splicing mechanism that is mediated by the endonuclease inositol-requiring enzyme 1 (IRE1). The resulting loss of 26 nt from the spliced mRNA causes a frame-shift and an isoform XBP1(S), which is the functionally active transcription factor.
Product Categories/Family for anti-XBP1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
40,148 Da
NCBI Official Full Name
X-box-binding protein 1 isoform XBP1(S)
NCBI Official Synonym Full Names
X-box binding protein 1
NCBI Official Symbol
XBP1
NCBI Official Synonym Symbols
XBP2; TREB5; XBP-1; TREB-5
NCBI Protein Information
X-box-binding protein 1
UniProt Protein Name
X-box-binding protein 1
UniProt Gene Name
XBP1
UniProt Synonym Gene Names
TREB-5
UniProt Entry Name
XBP1_HUMAN
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Product Notes
The XBP1 xbp1 (Catalog #AAA307150) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The XBP1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's XBP1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the XBP1 xbp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "XBP1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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