SDS-PAGE
(SDS-PAGE gel image The purity of SARS-CoV Spike protein RBD was determined to be >90% by densitometry. Approx. MW 65 kDa.)
SARS-CoV Spike RBD Recombinant Protein
SARS-CoV Spike Protein RBD
Synonyms
SARS-CoV Spike RBD; N/A; SARS-CoV Spike Protein RBD; SARS Corona virus S1; Corona virus S2; Corona virus spike; cov spike; ncov S1; ncov S2; ncov RBD; Spike RBD; RBD; SARS-CoV Spike RBD recombinant protein
Host
CHO Cells
Form/Format
Recombinant protein stored in 50mM Tris-HCl, pH7.5, 90mM glycine
Concentration
1.0ug/ul (varies by lot)
Species
SARS-CoV
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
SDS-PAGE
(SDS-PAGE gel image The purity of SARS-CoV Spike protein RBD was determined to be >90% by densitometry. Approx. MW 65 kDa.)
SDS-PAGE
(SDS-PAGE gel image The purity of SARS-CoV Spike protein RBD was determined to be >90% by densitometry. Approx. MW 65 kDa.)
Application Data
(Binding ability measured in a functional ELISA. Immobilized human ACE2 (19-740) protein (Fc tag) can bind to SARS-CoV spike protein RBD (Fc tag).)
Application Data
(Binding ability measured in a functional ELISA. Immobilized human ACE2 (19-740) protein (Fc tag) can bind to SARS-CoV spike protein RBD (Fc tag).)
Application Data
(Binding ability measured in a functional ELISA. Anti-2019-nCoV Spike Protein binds to immobilized SARS-CoV Spike Protein RBD (Fc tag).)
Application Data
(Binding ability measured in a functional ELISA. Anti-2019-nCoV Spike Protein binds to immobilized SARS-CoV Spike Protein RBD (Fc tag).)
Related Product Information for SARS-CoV Spike RBD recombinant protein
Description: Recombinant SARS-CoV Spike Protein RBD (318-510) was expressed in CHO cells using a C-terminal human IgG1 Fc tag.
Background: The severe acute respiratory syndrome related novel Corona virus (SARS-CoV) has caused the 2002-2003 SARS epidemic that broke out in southern China, which spread to other regions of Asia, Europe and North America (1). The spike glycoprotein (S) of Corona virus belongs to the type I transmembrane protein containing two subunits, S1 and S2 (2), which is also known to be the key component to bind with host cells through the interaction with angiotensin-converting enzyme 2 (ACE2). SARS-CoV can specifically recognize ACE2 through its receptor binding domain (RBD) of S1 to initiate viral infection in humans (3).
Background: The severe acute respiratory syndrome related novel Corona virus (SARS-CoV) has caused the 2002-2003 SARS epidemic that broke out in southern China, which spread to other regions of Asia, Europe and North America (1). The spike glycoprotein (S) of Corona virus belongs to the type I transmembrane protein containing two subunits, S1 and S2 (2), which is also known to be the key component to bind with host cells through the interaction with angiotensin-converting enzyme 2 (ACE2). SARS-CoV can specifically recognize ACE2 through its receptor binding domain (RBD) of S1 to initiate viral infection in humans (3).
Product Categories/Family for SARS-CoV Spike RBD recombinant protein
References
1. Li F, et al: Receptor recognition and cross-species infections of SARS Corona virus. Antiviral Research. 2013, 100 (1): 246-254.
2. Xiao X, et al: The SARS-CoV S glycoprotein. Cell Mol Life Sci. 2004, 61 (19-20): 2428-30.
3. Wan Y, et al: Receptor Recognition by the novel Corona virus from Wuhan: An analysis based on decade-long structural studies of SARS Corona virus. Journal of virology. 2020: 94.
2. Xiao X, et al: The SARS-CoV S glycoprotein. Cell Mol Life Sci. 2004, 61 (19-20): 2428-30.
3. Wan Y, et al: Receptor Recognition by the novel Corona virus from Wuhan: An analysis based on decade-long structural studies of SARS Corona virus. Journal of virology. 2020: 94.
NCBI and Uniprot Product Information
Molecular Weight
65kDa
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Product Notes
The SARS-CoV Spike RBD (Catalog #AAA73182) is a Recombinant Protein produced from CHO Cells and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "SARS-CoV Spike RBD, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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