Sox2 recombinant protein
Sox2 protein
Applications
User optimized.
Purity
> 95% by SDS-PAGE and HPLC analysis.
Synonyms
Sox2; N/A; Sox2 protein; Sox-2; Sox-2 protein; Sox 2 protein; Sex Determining Region Y- box 2 protein; Sox 2; Sox2 recombinant protein
Host
E. coli
Purity/Purification
> 95% by SDS-PAGE and HPLC analysis.
Form/Format
Lyophilized from 10mM Sodium Acetate, pH 6.0. 2um sterile filtered. Reconstitute in water to 0.1-1.0mg/ml. Do not vortex.
Concentration
25ug/vial; lyophilized (varies by lot)
Sequence
Region of Sox2 protein corresponding to amino acids MYNMMETELK PPGPQQTSGG GGGNSTAAAA GGNQKNSPDR VKRPMNAFMV WSRGQRRKMA QENPKMHNSE ISKRLGAEWK LLSETEKRPF IDEAKRLRAL HMKEHPDYKY RPRRKTKTLM KKDKYTLPGG LLAPGGNSMA SGVGVGAGLG AGVNQRMDSY AHMNGWSNGS YSMMQDQLGY PQHPGLNAHG AAQMQPMHRY DVSALQYNSM TSSQTYMNGS PTYSMSYSQQ GTPGMALGSM GSVVKSEASS SPPVVTSSSH SRAPCQAGDL RDMISMYLPG AEVPEPAAPS RLHMSQHYQS GPVPGTAING TLPLSHM.
Applicable Applications for Sox2 recombinant protein
User optimized.
Grade
Recombinant Human
Contaminants
Endotoxin level less than 0.1ng per ug.
Species
Human
Protein Type
Recombinant
Preparation and Storage
Ships on blue ice. Upon receipt store at -20°C. After reconstituted, can be stored at 4°C for up to 1 week. Working aliquots stored with a carrier protein are stable for at least 3 months at -20°C.
Related Product Information for Sox2 recombinant protein
Sox2, also known as sex determining region Y (SRY)-box 2, belongs to a diverse family of structurally-related transcription factors whose primary structure contains a 79-residue DNA-binding domain, called high mobility group (HMG) box. It plays an essential role in maintaining the pluripotency of embryonic stem cells (ESC) and determination of cell fate. Microarray analysis showed that Sox2 regulates the expression of multiple genes involved in embryonic development including FGF4, YES1 and ZFP206. Sox2 acts as a transcriptional activator after forming a ternary complex with Oct3/4 and a conserved non-coding DNA sequence (CNS1) located approximately 2 kb upstream of the RAX promoter. The introduction of Sox2, Oct4, Myc, and Klf4, into human dermal fibroblasts isolated from a skin biopsy of a healthy research fellow was sufficient to confer a pluripotent state upon the fibroblast genome.
Product Categories/Family for Sox2 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
Molecular Weight
34.3 kDa
NCBI Official Full Name
Sox2, partial
UniProt Protein Name
Sox2
UniProt Gene Name
Sox2
UniProt Entry Name
A4GU07_OREMO
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Product Notes
The Sox2 sox2 (Catalog #AAA14395) is a Recombinant Protein produced from E. coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Sox2 can be used in a range of immunoassay formats including, but not limited to, User optimized. Researchers should empirically determine the suitability of the Sox2 sox2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Region of Sox2 protein correspond ing to amino acids MYNMMETELK PPGPQQTSGG GGGNSTAAAA GGNQKNSPDR VKRPMNAFMV WSRGQRRKMA QENPKMHNSE ISKRLGAEWK LLSETEKRPF IDEAKRLRAL HMKEHPDYKY RPRRKTKTLM KKDKYTLPGG LLAPGGNSMA SGVGVGAGLG AGVNQRMDSY AHMNGWSNGS YSMMQDQLGY PQHPGLNAHG AAQMQPMHRY DVSALQYNSM TSSQTYMNGS PTYSMSYSQQ GTPGMALGSM GSVVKSEASS SPPVVTSSSH SRAPCQAGDL RDMISMYLPG AEVPEPAAPS RLHMSQHYQS GPVPGTAING TLPLSHM. It is sometimes possible for the material contained within the vial of "Sox2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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