SDS-PAGE
STAT2 recombinant protein
STAT2 recombinant protein
Gene Names
STAT2; P113; ISGF-3; STAT113
Applications
Western Blot
Synonyms
STAT2; N/A; STAT2 recombinant protein; STAT113; ISGF-3; MGC59816; P113
Host
Sf9 insect cells
Form/Format
50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Sequence Length
4576
Applicable Applications for STAT2 recombinant protein
WB (Western Blot), Kinase Assay
Type
Recombinant Fusion Protein
Species
Human
Tag Information
GST tag
Expression System
Sf9 insect cells using baculovirus
Source Note
Recombinant full-length human STAT2 was expressed by baculovirus in Sf9 insect cells
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Store product at -70 degree C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
SDS-PAGE
SDS-PAGE
Related Product Information for STAT2 recombinant protein
Recombinant full-length human STAT2 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Scientific Background: STAT2 (Signal transducer and activator of transcription) is a family member of STAT transcription factors that are implicated in programming gene expression in biological events as diverse as embryonic development, programmed cell death, organogenesis, innate immunity, adaptive immunity and cell growth regulation (1). JAKs can phosphorylate and activate STATs. Activation of the JAK/STAT pathway in response to cytokine action can lead to regulation of gene expression during proliferation and differentiation of the immune cells. STATs have been shown to be involved in inflammation, autoimmune and allergic diseases (2).
Scientific Background: STAT2 (Signal transducer and activator of transcription) is a family member of STAT transcription factors that are implicated in programming gene expression in biological events as diverse as embryonic development, programmed cell death, organogenesis, innate immunity, adaptive immunity and cell growth regulation (1). JAKs can phosphorylate and activate STATs. Activation of the JAK/STAT pathway in response to cytokine action can lead to regulation of gene expression during proliferation and differentiation of the immune cells. STATs have been shown to be involved in inflammation, autoimmune and allergic diseases (2).
Product Categories/Family for STAT2 recombinant protein
References
1. Horvath, C.M.: STAT proteins and transcriptional responses to extracellular signals. Trends Biochem Sci. 2000 Oct;25(10):496-502.
2. Pfitzner, E. et al: The role of STATs in inflammation and inflammatory diseases. Curr Pharm Des. 2004;10(23):2839-50.
2. Pfitzner, E. et al: The role of STATs in inflammation and inflammatory diseases. Curr Pharm Des. 2004;10(23):2839-50.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
~138 kDa
NCBI Official Full Name
Homo sapiens signal transducer and activator of transcription 2, 113kDa (STAT2), transcript variant 1, mRNA
NCBI Official Synonym Full Names
signal transducer and activator of transcription 2, 113kDa
NCBI Official Symbol
STAT2
NCBI Official Synonym Symbols
P113; ISGF-3; STAT113
NCBI Protein Information
signal transducer and activator of transcription 2; interferon alpha induced transcriptional activator
UniProt Protein Name
Signal transducer and activator of transcription 2
UniProt Gene Name
STAT2
UniProt Entry Name
STAT2_HUMAN
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Product Notes
The STAT2 stat2 (Catalog #AAA72903) is a Recombinant Protein produced from Sf9 insect cells and is intended for research purposes only. The product is available for immediate purchase. The tag for this protein is GST tag!!Expression System||Sf9 insect cells using baculovirus!!Source Note||Recombinant full-length human STAT2 was expressed by baculovirus in Sf9 insect cells. AAA Biotech's STAT2 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), Kinase Assay. Researchers should empirically determine the suitability of the STAT2 stat2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "STAT2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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