Thrombospondin-1 Recombinant Protein | TSP-1 recombinant protein
Human Thrombospondin-1 Recombinant
Purity
>90%, as determined by SDS-PAGE and HPLC
Synonyms
Thrombospondin-1; N/A; Human Thrombospondin-1 Recombinant; thrmbospondin; THBS1; tsp; TSP-1 recombinant protein
Host
Insect Cells (Host protein expression may be lot-specific and can be subject to change during production, including bulk orders)
Purity/Purification
>90%, as determined by SDS-PAGE and HPLC
Form/Format
Recombinant Thrombospondin-1 is lyophilized from PBS pH 7.4.
Host Note
Optimized DNA sequence encoding Human Thrombospondin mature chain was expressed in insect cells.
Endotoxin
Endotoxin content was assayed using a LAL gel clot method.
Endotoxin level was found to be less than 0.1 ng/ug (1EU/ug).
Endotoxin level was found to be less than 0.1 ng/ug (1EU/ug).
Molecular Weight Note
Native human Thrombospondin, generated by the proteolytic removal of the signal peptide and propeptide, and has a calculated molecular mass of approximately 128 kDa. Recombinant human TSP is a disulfide-linked monomer protein consisting of 1152 amino acid residue subunits, and migrates due to glycosylation as an approximately 140 kDa protein under non-reducing and reducing conditions in SDS-PAGE.
Preparation and Storage
The lyophilized protein is stable for at least 2 years from date of receipt at -20°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2-8°C for one month, or -20°C for six months, with a carrier protein withouth detectable loss of activity. Avoid repeated freeze/ thaw cycles.
Product Categories/Family for TSP-1 recombinant protein
References
• regulation of Thrombospondin-1 by natural and synthetic progestins in human breast cancer cells .Endocr. Relat. Cancer, Sep 2009; 16: 809 - 817.
• sjögren’s syndrome-like ocular surface disease in Thrombospondin-1 deficient mice .Am. J. Pathol., Sep 2009; 175: 1136 - 1147.
• interactions among stalk modules of Thrombospondin-1 .J. Biol. Chem., Aug 2009; 10.1074/jbc.M109.035089.
• interactions among the epidermal growth factor-like modules of Thrombospondin-1 .J. Biol. Chem., Aug 2009; 284: 22206 - 22212.
• Thrombospondin-1 is a transcriptional repression target of prmt6 .J. Biol. Chem., Aug 2009; 284: 21338 - 21346.
• sjögren’s syndrome-like ocular surface disease in Thrombospondin-1 deficient mice .Am. J. Pathol., Sep 2009; 175: 1136 - 1147.
• interactions among stalk modules of Thrombospondin-1 .J. Biol. Chem., Aug 2009; 10.1074/jbc.M109.035089.
• interactions among the epidermal growth factor-like modules of Thrombospondin-1 .J. Biol. Chem., Aug 2009; 284: 22206 - 22212.
• Thrombospondin-1 is a transcriptional repression target of prmt6 .J. Biol. Chem., Aug 2009; 284: 21338 - 21346.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
thrombospondin-1
UniProt Protein Name
Thrombospondin-1
UniProt Gene Name
THBS1
UniProt Synonym Gene Names
TSP; TSP1
UniProt Entry Name
TSP1_HUMAN
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Product Notes
The TSP-1 thbs1 (Catalog #AAA76099) is a Recombinant Protein produced from Insect Cells (Host protein expression may be lot-specific and can be subject to change during production, including bulk orders) and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Thrombospondin-1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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