SDS-PAGE
TIMP-1 recombinant protein
Recombinant Human TIMP-1 protein (His tag)
Gene Names
TIMP1; EPA; EPO; HCI; CLGI; TIMP
Purity
>95 % as determined by reducing SDS-PAGE.
Synonyms
TIMP-1; N/A; Recombinant Human TIMP-1 protein (His tag); Metalloproteinase Inhibitor 1; Erythroid-Potentiating Activity; EPA; Fibroblast collagenase Inhibitor; Collagenase Inhibitor; Tissue Inhibitor of Metalloproteinases 1; TIMP1; CLGI; TIMP; EPO; HCI; TIMP-1 recombinant protein
Host
HEK293 Cells-derived Human TIMP-1 protein Met1-Ala207, with an C-terminal His
Purity/Purification
>95 % as determined by reducing SDS-PAGE.
Form/Format
Lyophilized from a 0.2 um filtered solution in PBS with 5% Trehalose and 5% Mannitol
Sequence
Met1-Ala207
Endotoxin
< 1.0 EU/mg of the protein as determined by the LAL method
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/ml. Concentration is measured by UV-Vis
Preparation and Storage
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 degree C. Reconstituted protein solution can be stored at 4-8 degree C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 degree C for 3 months.
SDS-PAGE
SDS-PAGE
Related Product Information for TIMP-1 recombinant protein
Tissue Inhibitor of Metalloproteinases 1 (TIMP-1) is a member of TIMP family. The homologous proteins of TIMPs regulate the activity of matrix metalloproteinases (MMPs), including inhibition of active MMPs, proMMP activation, cell growth promotion, matrix binding, inhibition of angiogenesis and the induction of apoptosis. Timp-1 complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. It also mediates erythropoiesis in vitro; but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. It is known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13, and MMP-16, without MMP-14.
Product Categories/Family for TIMP-1 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
22.7 kDa
NCBI Official Full Name
metalloproteinase inhibitor 1
NCBI Official Synonym Full Names
TIMP metallopeptidase inhibitor 1
NCBI Official Symbol
TIMP1
NCBI Official Synonym Symbols
EPA; EPO; HCI; CLGI; TIMP
NCBI Protein Information
metalloproteinase inhibitor 1; TIMP-1; collagenase inhibitor; erythroid potentiating activity; erythroid-potentiating activity; fibroblast collagenase inhibitor; tissue inhibitor of metalloproteinases 1
UniProt Protein Name
Metalloproteinase inhibitor 1
UniProt Gene Name
TIMP1
UniProt Synonym Gene Names
CLGI; TIMP; EPA; Collagenase inhibitor; TIMP-1
UniProt Entry Name
TIMP1_HUMAN
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Product Notes
The TIMP-1 timp1 (Catalog #AAA178169) is a Recombinant Protein produced from HEK293 Cells-derived Human TIMP-1 protein Met1-Ala207, with an C-terminal His and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Met1-Ala20 7. It is sometimes possible for the material contained within the vial of "TIMP-1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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