Bioactivity
(Human TNFSF15 induces apoptosis in TF-1 human erythroleukemic cells in the presence of cycloheximaide. The ED50 range )
TL1A/TNFSF15 recombinant protein
Recombinant human TL1A/TNFSF15 protein
Gene Names
TNFSF15; TL1; TL1A; VEGI; VEGI192A
Applications
SDS-Page
Purity
> 90% by SDS-PAGE
Synonyms
TL1A/TNFSF15; N/A; Recombinant human TL1A/TNFSF15 protein; Tumor necrosis factor ligand superfamily member 15; TL1; TL1A; VEGI; VEGI192A; TL1A/TNFSF15 recombinant protein
Host
E Coli
Purity/Purification
> 90% by SDS-PAGE
Form/Format
Liquid in. 20mM Tris-HCl buffer (pH 8.5) containing 0.15M NaCl, 40% glycerol
Concentration
0.5mg/ml (determined by Bradford assay) (varies by lot)
Sequence Positions
72-251aa
Sequence
Applicable Applications for TL1A/TNFSF15 recombinant protein
Bioactivity, SDS-PAGE
Species
Human
Tag
His-Tag
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity
Measured by its ability to induce apoptosis in TF-1 human erythroleukemic cells in the presence of cycloheximaide. The ED50 range <= 100ng/ml.
Preparation and Storage
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Bioactivity
(Human TNFSF15 induces apoptosis in TF-1 human erythroleukemic cells in the presence of cycloheximaide. The ED50 range )
Bioactivity
(Human TNFSF15 induces apoptosis in TF-1 human erythroleukemic cells in the presence of cycloheximaide. The ED50 range )
SDS-PAGE
(3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain)
SDS-PAGE
(3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain)
Related Product Information for TL1A/TNFSF15 recombinant protein
Tumor necrosis factor ligand superfamily member 15, also known TNFSF15, belongs to the TNF superfamily. TNFSF15 is predominantly expressed in endothelial cells and its expression is inducible by TNFalpha and IL1alpha. TNFSF15 is an angiogenesis inhibitor of the TNF family and functions in part by directly inhibiting endothelial cell proliferation. TNFSF15 may act as an autocrine factor to induce apoptosis in endothelial cells via activation of multiple signaling pathways, including stress protein kinases and certain caspases. Recombinant human TNFSF15 protein, fused to His-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography techniques.
Product Categories/Family for TL1A/TNFSF15 recombinant protein
References
Migone T S., et al. (2002) Immunity. 16:479.;; Zhai Y., et al. (1999) FASEB J.13:181-189.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
20,131 Da
NCBI Official Full Name
tumor necrosis factor ligand superfamily member 15 isoform VEGI-251
NCBI Official Synonym Full Names
tumor necrosis factor (ligand) superfamily, member 15
NCBI Official Symbol
TNFSF15
NCBI Official Synonym Symbols
TL1; TL1A; VEGI; VEGI192A
NCBI Protein Information
tumor necrosis factor ligand superfamily member 15; TNF superfamily ligand TL1A; TNF ligand-related molecule 1; vascular endothelial cell growth inhibitor; vascular endothelial growth inhibitor-192A
UniProt Protein Name
Tumor necrosis factor ligand superfamily member 15
UniProt Gene Name
TNFSF15
UniProt Synonym Gene Names
TL1; VEGI
UniProt Entry Name
TNF15_HUMAN
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Product Notes
The TL1A/TNFSF15 tnfsf15 (Catalog #AAA48421) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 72-251aa. AAA Biotech's TL1A/TNFSF15 can be used in a range of immunoassay formats including, but not limited to, Bioactivity, SDS-PAGE. Researchers should empirically determine the suitability of the TL1A/TNFSF15 tnfsf15 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below:Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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