SDS-PAGE
(Human TSH Receptor/TSHR (His Tag))
TSHR recombinant protein
TSHR Protein, Human, Recombinant (ECD, His Tag)
Gene Names
TSHR; LGR3; CHNG1; hTSHR-I
Purity
>85% as determined by SDS-PAGE
Synonyms
TSHR; N/A; TSHR Protein, Human, Recombinant (ECD, His Tag); Human TSH Receptor/TSHR (His Tag); CHNG1 Protein, Human; hTSHR-I Protein, Human; LGR3 Protein, Human; TSH Receptor Protein, Human; TSHR Protein, Human; TSHR recombinant protein
Host
Baculovirus-Insect Cells
Purity/Purification
>85% as determined by SDS-PAGE
Form/Format
Lyophilized from sterile 50mM Tris, 150mM NaCl, 10% Glycerol, 1mM TCEP, pH7.5. Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Sequence
Gly21-Gly413
Source
Human
Endotoxin
<1.0EU per ug protein as determined by the LAL method.
Predicted N Terminal
Gly
Tag
C-His
Protein Construction
A DNA sequence encoding the human TSHR (NP_000360.2)(Gly21-Gly413) was expressed with a polyhistidine tag at the C-terminus.
Reconstitution
It is recommended that sterile water (1600 ul) be added to the vial to concentration is mesured by UV-Vis.
Molecular Mass
The recombinant human TSHR consists of 404 amino acids and predicts a molecular mass of 46.1 kDa. It migrates as an approximately 56.6 KDa band in SDS-PAGE under reducing conditions.
Reconstitution
It is recommended that sterile water (800ul) be added to the vial to prepare a stock solution of 0.25mg/mL
Concentration is mesured by UV.
Concentration is mesured by UV.
Preparation and Storage
Samples are stable for twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C upon receiving. Recommend to aliquot the protein into smaller quantities for optimal storage.
SDS-PAGE
(Human TSH Receptor/TSHR (His Tag))
SDS-PAGE
(Human TSH Receptor/TSHR (His Tag))
Related Product Information for TSHR recombinant protein
Background: Thyroid-stimulating hormone (TSH) is secreted by the pituitary gland and promotes thyroid growth and function, with increased TSH levels typically associated with hypothyroidism. Immunohistochemical analysis revealed predominantly nuclei/peri-nuclei localization of TSHR in cancerous tissues but cell membrane localization in non-cancerous parts. Overexpression of TSHR was found in a great majority of HCC tissues and associated with unfavorable prognosis.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
The recombinant human TSHR consists of 404 amino acids and predicts a molecular mass of 4631 kDa.
NCBI Official Full Name
thyrotropin receptor isoform 1
NCBI Official Synonym Full Names
thyroid stimulating hormone receptor
NCBI Official Symbol
TSHR
NCBI Official Synonym Symbols
LGR3; CHNG1; hTSHR-I
NCBI Protein Information
thyrotropin receptor; thyrotropin receptor-I, hTSHR-I; seven transmembrane helix receptor; thyroid stimulating hormone receptor, isoform 2
UniProt Protein Name
Thyrotropin receptor
UniProt Gene Name
TSHR
UniProt Synonym Gene Names
LGR3; TSH-R
UniProt Entry Name
TSHR_HUMAN
Similar Products
Product Notes
The TSHR tshr (Catalog #AAA258058) is a Recombinant Protein produced from Baculovirus-Insect Cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Gly21-Gly4 13. It is sometimes possible for the material contained within the vial of "TSHR, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.