Werner syndrome ATP-dependent helicase (WRN) Recombinant Protein | WRN recombinant protein
Recombinant Human Werner syndrome ATP-dependent helicase (WRN), partial
Gene Names
WRN; RECQ3; RECQL2; RECQL3
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Werner syndrome ATP-dependent helicase (WRN); N/A; Recombinant Human Werner syndrome ATP-dependent helicase (WRN), partial; WRN recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
500-946aa; Partial
Sequence
NLGLPTKEEEEDDENEANEGEEDDDKDFLWPAPNEEQVTCLKMYFGHSSFKPVQWKVIHSVLEERRDNVAVMATGYGKSLCFQYPPVYVGKIGLVISPLISLMEDQVLQLKMSNIPACFLGSAQSENVLTDIKLGKYRIVYVTPEYCSGNMGLLQQLEADIGITLIAVDEAHCISEWGHDFRDSFRKLGSLKTALPMVPIVALTATASSSIREDIVRCLNLRNPQITCTGFDRPNLYLEVRRKTGNILQDLQPFLVKTSSHWEFEGPTIIYCPSRKMTQQVTGELRKLNLSCGTYHAGMSFSTRKDIHHRFVRDEIQCVIATIAFGMGINKADIRQVIHYGAPKDMESYYQEIGRAGRDGLQSSCHVLWAPADINLNRHLLTEIRNEKFRLYKLKMMAKMEKYLHSSRCRRQIILSHFEDKQVQKASLGIMGTEKCCDNCRSRLDHC
Species
Human
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for WRN recombinant protein
This gene encodes a member of the RecQ subfamily and the DEAH (Asp-Glu-Ala-His) subfamily of DNA and RNA helicases. DNA helicases are involved in many aspects of DNA metabolism, including transcription, replication, recombination, and repair. This protein contains a nuclear localization signal in the C-terminus and shows a predominant nucleolar localization. It possesses an intrinsic 3 to 5 DNA helicase activity, and is also a 3 to 5 exonuclease. Based on interactions between this protein and Ku70
80 heterodimer in DNA end processing, this protein may be involved in the repair of double strand DNA breaks. Defects in this gene are the cause of Werner syndrome, an autosomal recessive disorder characterized by premature aging.
80 heterodimer in DNA end processing, this protein may be involved in the repair of double strand DNA breaks. Defects in this gene are the cause of Werner syndrome, an autosomal recessive disorder characterized by premature aging.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
7486
NCBI Official Full Name
Werner syndrome ATP-dependent helicase
NCBI Official Synonym Full Names
Werner syndrome RecQ like helicase
NCBI Official Symbol
WRN
NCBI Official Synonym Symbols
RECQ3; RECQL2; RECQL3
NCBI Protein Information
Werner syndrome ATP-dependent helicase
UniProt Protein Name
Werner syndrome ATP-dependent helicase
UniProt Gene Name
WRN
UniProt Synonym Gene Names
RECQ3; RECQL2; RecQ3
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Product Notes
The WRN wrn (Catalog #AAA244048) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 500-946aa; Partial. The amino acid sequence is listed below: NLGLPTKEEE EDDENEANEG EEDDDKDFLW PAPNEEQVTC LKMYFGHSSF KPVQWKVIHS VLEERRDNVA VMATGYGKSL CFQYPPVYVG KIGLVISPLI SLMEDQVLQL KMSNIPACFL GSAQSENVLT DIKLGKYRIV YVTPEYCSGN MGLLQQLEAD IGITLIAVDE AHCISEWGHD FRDSFRKLGS LKTALPMVPI VALTATASSS IREDIVRCLN LRNPQITCTG FDRPNLYLEV RRKTGNILQD LQPFLVKTSS HWEFEGPTII YCPSRKMTQQ VTGELRKLNL SCGTYHAGMS FSTRKDIHHR FVRDEIQCVI ATIAFGMGIN KADIRQVIHY GAPKDMESYY QEIGRAGRDG LQSSCHVLWA PADINLNRHL LTEIRNEKFR LYKLKMMAKM EKYLHSSRCR RQIILSHFED KQVQKASLGI MGTEKCCDNC RSRLDHC. It is sometimes possible for the material contained within the vial of "Werner syndrome ATP-dependent helicase (WRN), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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