Mouse RABIES VIRUS GLYCOPROTEIN Monoclonal Antibody

MOUSE ANTI RABIES VIRUS GLYCOPROTEIN

Cat. Num. AAA12061

• Applications: Immunohistochemistry, ELISA, Functional Assay, Immunofluorescence
• Synonyms: RABIES VIRUS GLYCOPROTEIN; Monoclonal Antibody; MOUSE ANTI RABIES VIRUS GLYCOPROTEIN; anti-RABIES VIRUS GLYCOPROTEIN antibody

• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG2a
• Clone Number: 1C5
• Specificity: Rabies Virus Glycoprotein
• Form/Format: Purified IgG - liquid
• Concentration: IgG concentration 1.0 mg/ml (varies by lot)

• Applicable Applications for anti-RABIES VIRUS GLYCOPROTEIN antibody: Immunohistology Frozen (IHC-F), ELISA (EIA), Functional Assays (FN), Immunofluorescence (IF)
• Application Notes: Where this antibody has been tested for use in a particular technique this does not necessarily exclude its use in such procedures. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.; (1) Sodium azide needs to be removed by dialysis before use of this antibody in funcitonal assay.
• Preservative Stabilizers: <0.1% Sodium Azide (NaN₃)
• Preparation: Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
• RRID: AB_1125351
• Immunogen: Purified rabies virus
• Fusion Partners: Spleen cells from immunized Balb/c mice were fused with cells of the Sp2/0 myeloma cells.
• Buffer Solution: Phosphate buffered saline
• Target Species: Viral
• Preparation and Storage: It is recommended to aliquot and store at -20 degree C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2 to 8 degree C for short term use (up to 4 weeks) and store the remaining aliquots at -20 degree C. Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.

Related Product Information for anti-RABIES VIRUS GLYCOPROTEIN antibody

Mouse anti Rabies Virus Glycoprotein antibody, clone 1C5 recognizes the glycoprotein of rabies virus, a Lyssavirus that causes rabies in mammals. The virus is found in the saliva of infected animals and is mostly spread though bites. The virus then travels though the peripheral nervous system to the central nervous system. Once it reaches the brain it causes acute encephalitis. Symptoms include paralysis, cerebral dysfunction, anxiety, insomnia, confusion, anger, paranoia, terror and hallucination. The production of a large amount of saliva, the inability to speak or swallow and associated hydrophobia is also common in the later stages of the disease. The time between exposure to the virus and onset of symptoms can range from about 2 weeks to several months. Once symptoms appear, death is virtually inevitable. However, the disease can be effectively treated by post-exposure prophylaxis, through vaccination, provided this is done as soon as possible.
Mouse anti Rabies Virus Glycoprotein antibody, clone 1C5 recognizes the purified glycoprotein of the rabies virus as well as the native virus. It has been shown to react with intact infected BHK cells and has therapeutic effect on infected mice. The antibody has virus-neutralising activity with several rabies virus strains such as CVS, Lagos bat, Mokola, Flury LEP and Duvenhage.

NCBI and Uniprot Product Information