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Active Proteins

AAA Biotech also known as AAA Bio or AAABio provides a variety of high-quality recombinant and natural/native proteins that are proven to work in a wide range of experiments. Explore our products to find the active protein that best fits your needs or experimental model.


Viewing 2100-2150 of 2567 product results


Neurotrophin-3, Active Protein (Cat# AAA38136)

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Full Name
Recombinant Human Neurotrophin-3
Gene Names
NTF3; NT3; HDNF; NGF2; NT-3; NGF-2
Purity
Greater than 98.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Interleukin-4, Active Protein (Cat# AAA38143)

No reviews yet
Full Name
Recombinant Mouse Interleukin-4
Gene Names
Il4; Il-4; BSF-1
Purity
Greater than 96.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Flt3-Ligand, Active Protein (Cat# AAA38161)

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Full Name
Recombinant Human Flt3-Ligand
Gene Names
FLT3LG; FL; FLT3L
Purity
Greater than 95.0% as determined by(a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Interleukin-9, Active Protein (Cat# AAA38171)

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Full Name
Recombinant Human Interleukin-9
Gene Names
IL9; P40; HP40; IL-9
Purity
Greater than 98.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Vascular Endothelial Growth Factor, Active Protein (Cat# AAA38186)

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Full Name
Recombinant Rat Vascular Endothelial Growth Factor
Gene Names
Vegfa; VPF; Vegf; VEGF-A; VEGF164
Purity
Greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing

BGrowth Hormone, Active Protein (Cat# AAA38653)

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Full Name
Recombinant Bovine Growth Hormone
Gene Names
GH1; GH
Purity
Greater than 98.0% as determined by: (a) Analysis by SEC-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Carboxypeptidase-B, Active Protein (Cat# AAA38666)

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Full Name
Recombinant Rat Carboxypeptidase-B
Gene Names
Cpb1; Cpb
Purity
Greater than 90% as determined by SDS-PAGE.
Pricing

Thioredoxin Reductase, Active Protein (Cat# AAA38784)

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Full Name
Recombinant E Coli Thioredoxin Reductase
Gene Names
trxB; ECK0879; JW0871
Purity
Greater than 90% as determined by SDS-PAGE.
Pricing

Malate Dehydrogenase 1, Active Protein (Cat# AAA38835)

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Full Name
Recombinant Human Malate Dehydrogenase 1
Gene Names
MDH1; MDHA; MOR2; MDH-s; HEL-S-32; MGC:1375
Purity
Greater than 95.0% as determined by SDS-PAGE.
Pricing

Complement Component C5a, Active Protein (Cat# AAA39018)

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Full Name
Recombinant Mouse Complement Component C5a
Gene Names
Hc; C5; He; C5a
Purity
Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Interleukin-8, Active Protein (Cat# AAA38923)

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Full Name
Recombinant Rhesus Macaque Interleukin-8
Gene Names
CXCL8; IL8; NAF; GCP1; LECT; LUCT; NAP1; GCP-1; LYNAP; MDNCF; MONAP; NAP-1
Purity
Greater than 97.0% as determined by SDS-PAGE.
Pricing

Follistatin, Active Protein (Cat# AAA38937)

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Full Name
Recombinant Mouse Follistatin
Gene Names
Fst; FS; AL033346
Purity
Greater than 90.0% as determined by SDS-PAGE.
Pricing

Interleukin-27 p28, Active Protein (Cat# AAA39117)

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Full Name
Recombinant Human Interleukin-27 p28
Gene Names
IL27; p28; IL30; IL-27; IL27A; IL-27A; IL27p28
Purity
Greater than 90% as determined by analysis by SDS-PAGE.
Pricing

Prolyl 4-Hydroxylase Beta, Active Protein (Cat# AAA39146)

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Full Name
Recombinant Human Prolyl 4-Hydroxylase Beta, Active
Gene Names
P4HB; DSI; GIT; PDI; PHDB; PDIA1; PO4DB; PO4HB; PROHB; CLCRP1; ERBA2L; P4Hbeta
Purity
Greater than 90.0% as determined by SDS-PAGE.
Pricing

prolactin receptor antagonist, Active Protein (Cat# AAA39185)

No reviews yet
Full Name
Human prolactin receptor antagonist - SUPER ACTIVE
Purity
Greater than 97.0% as determined by: (a) Gel filtration analysis (size exclusion chromtography). (b) Analysis by reducing and non-reducing SDS-PAGE gel.
Pricing

APRIL, Active Protein (Cat# AAA75589)

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Full Name
APRIL protein
Gene Names
TNFSF13; APRIL; CD256; TALL2; ZTNF2; TALL-2; TRDL-1; UNQ383/PRO715
Purity
> or = 95% pure by SDS-PAGE gel and HPLC
Pricing
product-image-AAA78521_ACTIVITY15.png Activity (Figure 1 : ACE2 (human)(rec.) (AAA78521) binds with high affinity to the Spike (RBD) protein of the virus SARS-CoV-2. Method: ACE2 (human)(rec.) (AAA78521 ) is coated on an ELISA plate at 1 ug/ml overnight at 4°C. Spike (SARS-CoV-2):Fc (human)(RBD)(rec.) is added (starting at a concentration of 500 ng/ml with a twofold serial dilution) during one hour at RT and the interaction is then detected using an anti-human IgG (HRP).)

ACE2, Active Protein (Cat# AAA78521)

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Full Name
Human ACE2 Protein (DYKDDDDK Tag)
Applications
Functional Assay
Purity
>95% (SDS-PAGE)
Pricing

Apo Transferrin (ATF), Active Protein (Cat# AAA76530)

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Full Name
Human Apo Transferrin (ATF)
Reactivity
Human
Purity
Greater than 98.0% as determined by Cellulose Acetate Electrophoresis.
Pricing

gamma-Glutamyl Transferase, Active Protein (Cat# AAA44798)

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Full Name
Gamma-glutamyl Transferase (gGT), Porcine Kidney
Gene Names
GGT1; GGT; GTG; CD224; GGT 1; D22S672; D22S732
Purity
Purified

Plasminogen, Active Protein (Cat# AAA44858)

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Full Name
Plasminogen (PLG), Human Plasma
Gene Names
PLG; LPA
Purity
>95% (SDS-PAGE)
Pricing

TGF-beta RI/ALK-5, Active Protein (Cat# AAA48990)

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Full Name
Recombinant human TGF-beta RI/ALK-5 protein
Gene Names
TGFBR1; AAT5; ALK5; ESS1; LDS1; MSSE; SKR4; ALK-5; LDS1A; LDS2A; TGFR-1; ACVRLK4
Applications
Bioactivity, SDS-PAGE
Purity
> 90% by SDS-PAGE
Pricing

Prostate Specific Antigen, Active Protein (Cat# AAA59627)

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Full Name
Prostate Specific Antigen, Human
Gene Names
KLK3; APS; PSA; hK3; KLK2A1
Purity
>/= 95% by SDS-PAGE
Pricing
product-image-AAA258026_SDS_PAGE15.jpg SDS-PAGE

DNase I, Active Protein (Cat# AAA258026)

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Full Name
DNase I Protein, Human, Recombinant (His Tag)
Gene Names
DNASE1; DNL1; DRNI
Purity
>85% as determined by SDS-PAGE
Pricing
product-image-AAA258028_AD13.png Application Data (Measured by its binding ability in a functional ELISA. Immobilized human TMIGD2 at 10 ug/mL (100 uL/well) can bind human HHLA2-Fc, the EC50 of human HHLA2-Fc is 0.3-3ug/mL.)

TMIGD2, Active Protein (Cat# AAA258028)

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Full Name
TMIGD2 Protein, Human, Recombinant (His Tag)
Gene Names
TMIGD2; CD28H; IGPR1; IGPR-1
Purity
>85% as determined by Nu-PAGE
Pricing
product-image-AAA214279_AD13.png Application Data

Fractalkine (CX3CL1), Active Protein (Cat# AAA214279)

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Full Name
Recombinant Human Fractalkine (CX3CL1)
Gene Names
CX3CL1; NTN; NTT; CXC3; CXC3C; SCYD1; ABCD-3; C3Xkine; fractalkine; neurotactin
Purity
>95% as determined by SDS-PAGE
Pricing
product-image-AAA244032_BIOACTIVITY13.png Bioactivity

Spike glycoprotein (S), Active Protein (Cat# AAA244032)

No reviews yet
Full Name
Recombinant Human Novel Coronavirus Spike glycoprotein (S), partial
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing
product-image-AAA153010_BIOACTIVITY13.jpg Bioactivity (Procollagen II N-Terminal Propeptide is specific for cartilaginous tissues. It is essential for the normal embryonic development of the skeleton, for linear growth and for the ability of cartilage to resist compressive forces, which was are associated wit)

Procollagen II N-Terminal Propeptide (PIINP), Active Protein (Cat# AAA153010)

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Full Name
Active Procollagen II N-Terminal Propeptide (PIINP)
Gene Names
COL2A1; AOM; ANFH; SEDC; COL11A3
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
product-image-AAA161788_BIOACTIVITY13.jpg Bioactivity (PRL (prolactin), also known as luteotropin, is a hormone secreted from the pituitary gland and is best known for its role in enabling mammals to produce milk. PRL plays an essential role in metabolism, regulation of the immune system through activating its specific membrane-anchored receptor (PRLR). A functional binding ELISA assay was conducted to detect the interaction of recombinant goat PRL and recombinant human PRLR. Briefly, PRL was diluted serially in PBS with 0.01% BSA (pH 7.4). Duplicate samples of 100 ul were then transferred to PRLR-coated microtiter wells and incubated for 1h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-PRL pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody for 1h at 37 degree C, wells were aspirated and washed 5 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50 uL stop solution to the wells and read at 450/630 nm immediately. The binding activity of recombinant goat PRL and recombinant human PRLR was shown in Figure 1, the EC50 for this effect is 0.1 ug/mL.)

Prolactin (PRL), Active Protein (Cat# AAA161788)

No reviews yet
Full Name
Active Prolactin (PRL)
Gene Names
PROLACTIN; PRL
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
product-image-AAA161811_BIOACTIVITY13.jpg Bioactivity (Aprotinin (AP) is a competitive serine protease inhibitor. Reversibly binds to and blocks the enzymatic active site. Inhibits a range of serine proteases including trypsin, chymotrypsin, kallikrein and plasmin. Inhibits cytopathogenic effect of SARS-CoV-2 and double-stranded RNA formation in SARS-CoV-2-infected cells. The activity of recombinant bovine AP was measured by its ability to inhibit trypsin cleavage of a peptide substrate BAPNA in the assay buffer 200 mM Triethanolamine hydrochloride, 20 mM CaCl2, pH 7.8. The reaction was performed in adding 20 ul 4 mg/mL trypsin diluted by 1mM HCl to 160 ul assay buffer and 20 ul 0.85% (w/v) NaCl and start the reaction by adding 100 ul of 1mg/ml BAPNA. Include a substrate blank containing 160 ul assay buffer, 20 ul 1mM HCl, 20 ul 0.85% (w/v) NaCl and 100 uL of 1mg/ml substrate. Rapidly mixing at 25 degree C, then read at 405 nm in kinetic mode for 5 minutes using a microplate reader controlling the ?A405nm/min=0.08-0.12. The 20 ul different concentrations of recombinant bovine AP was incubated with 20 ul 4 mg/mL trypsin in 160 ul assay buffer at 25 degree C for 10 minutes followed by adding 100 ul substrate, then read at 405 nm in kinetic mode for 5 minutes using a microplate reader. Under these conditions, the enzyme amount of 50% inhibition of trypsin activity per minute is defined as a unit. The specific activity of recombinant bovine AP is >3000 U/mg.)

Aprotinin (AP), Active Protein (Cat# AAA161811)

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Full Name
Active Aprotinin (AP)
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
product-image-AAA161701_BIOACTIVITY13.jpg Bioactivity (Tissue Inhibitors of Metalloproteinase 4 (TIMP4) is an enzyme that in humans is encoded by the TIMP4 gene. This gene belongs to the tissue inhibitor of metalloproteinases gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. The secreted, netrin domain-containing protein encoded by this gene is involved in regulation of platelet aggregation and recruitment and may play role in hormonal regulation and endometrial tissue remodeling. The activity of recombinant bovine TIMP4 was measured by its ability to inhibit rhMMP2 cleavage of a fluorogenic peptide substrate MCA-Pro-Leu-Gly-Leu-DPA-Ala-Arg-NH2 in the assay buffer 50 mM Tris, 10 mM CaCl2, 150 mM NaCl, 0.05% (w/v) Brij-35, pH 7.5. rhMMP2 was diluted to 100 ug/ml and activated with 1 mM APMA at 37 degree C for 1 hour and rbTIMP4 (MW: 24.05 KD) was diluted to different concentrations with the assay buffer. Mix 8 ul of rbTIMP4 curve dilutions, 12.8 ul of activated rhMMP-2, and 59.2 ul of assay buffer, including a control containing assay buffer and the diluted rhMMP-2 and incubate the reactions for 2 hours at 37 degree C. Loading 50 ul of the incubated mixtures which were diluted five-fold in assay buffer into empty wells of a plate, and start the reaction by adding 50 ul of 20 uM substrate. Include a substrate blank containing 50 ul of assay buffer and 50 ul of 20 uM substrate. Then read at excitiation and emission wavelengths of 320 nm and 405 nm, respectively, in kinetic mode for 5 minutes. The result was shown in Figure 1 and it was obvious that recombinant bovine TIMP4 significantly decreased rhMMP2 activity. The inhibition IC50 was )

Tissue Inhibitors Of Metalloproteinase 4 (TIMP4), Active Protein (Cat# AAA161701)

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Full Name
Active Tissue Inhibitors Of Metalloproteinase 4 (TIMP4)
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
product-image-AAA161892_BIOACTIVITY13.jpg Bioactivity (Multimerin 1 (MMRN1) is a secreted glycoprotein that consists of multiple subunits, forming a complex with a molecular weight of approximately 150 kDa. MMRN1 is a member of the multimerin family and it is mainly expressed in platelets and endothelial cells. MMRN1 plays an important role in maintaining vascular integrity, regulating clotting and inflammatory responses, among others. In addition, the binding of MMRN1 to Vitronectin (VTN) plays an important role in a variety of physiological and pathological processes, including cell adhesion, migration, blood coagulation, and cell signaling. Thus a functional binding ELISA assay was conducted to detect the interaction of recombinant human MMRN1 and recombinant human VTN. Briefly, MMRN1 was diluted serially in PBS with 0.01% BSA (pH 7.4). Duplicate samples of 100 ul were then transferred to VTN-coated microtiter wells and incubated for 1h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-MMRN1 pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody for 1h at 37 degree C, wells were aspirated and washed 5 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50 uL stop solution to the wells and read at 450/630 nm immediately. The binding activity of recombinant human MMRN1 and recombinant human VTN was shown in Figure 1, and this effect was in a dose dependent manner.)

Multimerin 1 (MMRN1), Active Protein (Cat# AAA161892)

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Full Name
Active Multimerin 1 (MMRN1)
Gene Names
MMRN1; ECM; MMRN; GPIa*; EMILIN4
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
product-image-AAA161665_BIOACTIVITY11.jpg Bioactivity (Figure 2. Cell proliferation of M-NFS-60 cells after stimulated with G-CSF.)

Colony Stimulating Factor 3, Granulocyte (GCSF), Active Protein (Cat# AAA161665)

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Full Name
Active Colony Stimulating Factor 3, Granulocyte (GCSF)
Gene Names
CSF3; G-CSF
Applications
Activity Assay, Cell Culture
Purity
Greater than 80% by SDS-PAGE
Pricing
product-image-AAA150099_BIOACTIVITY11.jpg Bioactivity (Figure. The binding activity of FGF23 with FGFR2.Fibroblast growth factor 23 or FGF23 is a member of the fibroblast growth factor (FGF) family which is responsible for phosphate and vitamin D metabolism. The main function of FGF23 seems to be regulation of phosphate concentration in plasma. FGF23 decreases the reabsorption and increases excretion of phosphate and suppress 1-alpha-hydroxylase, reducing its ability to activate vitamin D and subsequently impairing calcium absorption. Besides, Fibroblast Growth Factor Receptor 2 (FGFR2) has been identified as an interactor of FGF23, thus a binding ELISA assay was conducted to detect the interaction of recombinant human FGF23 and recombinant human FGFR2. Briefly, FGF23 were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100uL were then transferred to FGFR2-coated microtiter wells and incubated for 2h at 37. Wells were washed with PBST and incubated for 1h with anti-FGF23 pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of FGF23 and FGFR2 was shown in Figure 1, and this effect was in a dose dependent manner.)

Fibroblast Growth Factor 23, Active Protein (Cat# AAA150099)

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Full Name
Active Fibroblast Growth Factor 23 (FGF23)
Gene Names
FGF23; ADHR; FGFN; HYPF; HFTC2; HPDR2; PHPTC
Applications
Activity Assay, Cell Culture
Purity
>95%
Pricing
product-image-AAA150102_WB8.png WB (Western Blot) (Sample: Recombinant Lpa, Human;Antibody: Rabbit Anti-Human Lpa Ab)

Lipoprotein, a, Active Protein (Cat# AAA150102)

No reviews yet
Full Name
Active Lipoprotein, a (Lpa)
Gene Names
LPA; LP; AK38; APOA
Reactivity
Homo sapiens (Human)
Applications
Activity Assay, Cell Culture
Purity
>90%
Pricing

BAFF R/TNFRSF13C, Active Protein (Cat# AAA48988)

No reviews yet
Full Name
Recombinant human BAFF R/TNFRSF13C protein
Gene Names
TNFRSF13C; BAFFR; CD268; CVID4; BAFF-R; BROMIX; prolixin
Applications
Bioactivity, SDS-PAGE
Purity
> 95% by SDS-PAGE
Pricing
product-image-AAA48521_SDS_PAGE15.jpg SDS-PAGE

GSTM1, Active Protein (Cat# AAA48521)

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Full Name
GSTM1, 1-218aa, Mouse, E Coli (Bioactivity Validated)
Gene Names
Gstm1; Gstb1; Gstb-1
Applications
SDS-PAGE
Purity
> 95% by SDS-PAGE
Pricing

Pepsinogen II, Active Protein (Cat# AAA44860)

No reviews yet
Full Name
Pepsinogen II (PGII/PGC), Human Gastric Mucosa
Gene Names
PGC; PEPC; PGII
Applications
Western Blot
Purity
>90% (SDS-PAGE) may contain minor cleavage products.
Pricing

beta-Human Chorionic Gonadotrophin, Active Protein (Cat# AAA44799)

No reviews yet
Full Name
beta-Human Chorionic Gonadotropin (b-hCG)
Purity
>98% (SDS-PAGE)
Pricing

Keratinocyte Growth Factor-2, Active Protein (Cat# AAA38945)

No reviews yet
Full Name
Recombinant Mouse Keratinocyte Growth Factor-2
Gene Names
Fgf10; AEY17; Fgf-10; BB213776; Gsfaey17
Purity
Greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Pegylated Granulocyte-Colony, Active Protein (Cat# AAA38985)

No reviews yet
Full Name
Recombinant Human Pegylated Granulocyte-Colony Stimulating Factor
Gene Names
CSF3; GCSF; CSF3OS; C17orf33
Purity
Greater than 95.0% as determined by SEC-HPLC.
Pricing

Matrix Metalloproteinase-1, Active Protein (Cat# AAA39015)

No reviews yet
Full Name
Recombinant Human Matrix Metalloproteinase-1, HEK
Gene Names
MMP1; CLG; CLGN
Purity
Greater than 95% as determined by SDS-PAGE.
Pricing

Disulfide Isomerase A6, Active Protein (Cat# AAA39147)

No reviews yet
Full Name
Recombinant Human Protein Disulfide Isomerase A6, Active
Gene Names
PDIA6; P5; ERP5; TXNDC7
Purity
Greater than 90.0% as determined by SDS-PAGE.
Pricing
product-image-AAA41021_BIOACTIVITY13.jpg Bioactivity

COVID 19 Spike S1 Protein Coronavirus, Active Protein (Cat# AAA41021)

No reviews yet
Full Name
Recombinant SARS-CoV-2 (2019-nCoV) S1 Protein
Applications
Immunogen
Purity
>90% as determined by SDS-PAGE quantitative densitometry by Coomassie Blue staining.

Malate Dehydrogenase 2, Active Protein (Cat# AAA38044)

No reviews yet
Full Name
Recombinant Mouse Malate Dehydrogenase 2
Gene Names
Mdh2; MDH; Mor1; Mdh-2; Mor-1
Purity
Greater than 95.0% as determined by SDS-PAGE.
Pricing

Granzyme-B, Active Protein (Cat# AAA38045)

No reviews yet
Full Name
Recombinant Human Granzyme-B, Sf9
Gene Names
GZMB; C11; HLP; CCPI; CGL1; CSPB; SECT; CGL-1; CSP-B; CTLA1; CTSGL1
Purity
Greater than 95.0% as determined by SDS-PAGE.
Pricing

I-309, Active Protein (Cat# AAA38084)

No reviews yet
Full Name
Recombinant Human I-309 (CCL1)
Gene Names
CCL1; P500; SISe; TCA3; I-309; SCYA1
Purity
Greater than 99.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Growth Hormone, Active Protein (Cat# AAA38106)

No reviews yet
Full Name
Recombinant Human Growth Hormone
Gene Names
GH1; GH; GHN; GH-N; hGH-N; IGHD1B
Purity
Greater than 96.0% as determined by SDS-PAGE.
Pricing

Brain-Derived Neurotrophic Factor, Active Protein (Cat# AAA38107)

No reviews yet
Full Name
Recombinant Human Brain-Derived Neurotrophic Factor
Gene Names
BDNF; ANON2; BULN2
Purity
BDNF is greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing

FITC Labeled Bovine Fibrinogen, Active Protein (Cat# AAA37784)

No reviews yet
Full Name
FITC Labeled Bovine Fibrinogen
Purity
>95% by SDS-PAGE analysis
Pricing

Glutathione S-Transferase Alpha 1, Active Protein (Cat# AAA38702)

No reviews yet
Full Name
Recombinant Human Glutathione S-Transferase Alpha 1
Gene Names
GSTA1; GST2; GTH1; GSTA1-1
Purity
Greater than 90.0% as determined by SDS-PAGE.
Pricing

What Are Active Proteins?


Proteins are large molecules made up of long chains of amino acids. They will typically fold into a very particular 3-dimensional shape/conformation, that is sometimes referred to as their “native” form, which allows them to work properly in the body. For the purposes of product categorization, AAA Biotech will typically refer to proteins purified from their original animal host as being “native” proteins (this is to signify their difference compared to their recombinant proteins or “synthetic” protein counterparts).


If a protein successfully folds into the correct shape, it will typically display high fidelity characteristics to its original protein in its original animal host and be classified as an active protein, as it will be able to function “normally” in most enzymatic or binding capacities. If it loses this shape, due to factors such as heat or strong chemicals (such as detergents), it becomes inactive and is no longer able to perform its basic functions.


All of the proteins in this category are made under strict quality control, and they are active, pure, low in contaminants, and stable. Most are stored as freeze-dried powders and come without extra tags, so they’re very close to the actual natural/native form.


Learn more in our guide “How active proteins work”.


Key Applications of Active Proteins


1. Scientific Research


  • Aid in the study of how proteins function in the body

  • Aid in understanding various disease processes


2. Drug Development


  • Powerful tools to investigate how potential drugs interact with specific proteins

  • Ideal for identifying drug targets


3. Cell Culture


  • Are routinely utilized to support cell growth and function (e.g., using exogenous growth factors)

  • Can be used to promote cellular development into specific types (differentiation)


4. Diagnostics


  • Regularly utilized in tests to detect diseases or infections (e.g., COVID-19, cancer)

  • Note: All products are strictly for research-use only (RUO).


5. Therapeutics


  • Some active proteins are used directly as treatments (e.g., insulin, enzymes)

  • Note: All products are strictly for research-use only (RUO).


6. Vaccine Development


  • Used to create or test vaccines by mimicking parts of viruses or bacteria


7. Biochemical Assays


  • They can facilitate the characterization of enzyme activity, binding strength, or protein interactions in lab tests


Why Buy Active Proteins from AAA Biotech?


  • High biological activity – Verified to perform as expected or indicated on datasheet

  • Strict quality control – We are confident in our active proteins’ reliability and consistency

  • High purity & low endotoxin – Ideal for applications involving sensitive or precious samples/components

  • Freeze-dried for stability – Long shelf life and straightforward storage

  • Mostly tag-free – Closer to natural/native protein form


FAQ


1. What are active proteins used for in research?


Active proteins are used primarily in the study of how proteins function, in characterizing/discovering drug interactions, supporting cell growth, running biochemical assays, and in development of diagnostics or therapeutics.


2. How are AAA Biotech's active proteins validated?


AAA Biotech’s active proteins are validated through strict quality control and functional assays to ensure they are properly folded and active. “Active”, though, can be an ambiguous term, so if a specific “activity” or “binding” capability of a protein is of crucial interest to you, please inquire with us prior to purchase, and we will provide further details on how the “Active” modifier was determined to be applicable.


3. Are these proteins tested for biological activity?


Yes, all active proteins from AAA Biotech are tested to confirm they have the expected biological activity before being offered for use. Though, said “biological activity” can be either “enzymatic”, “binding”, or both.


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