Structure
(Cefoperazone dihydrate, CAS 113826-44-1)
alpha-Conotoxin ImI (trifluoroacetate salt) Biochemical
alpha-Conotoxin ImI (trifluoroacetate salt)
Purity
98%
Synonyms
alpha-Conotoxin ImI (trifluoroacetate salt); N/A; alpha-Conotoxin ImI (trifluoroacetate salt) biochemical
Purity/Purification
98%
Solubility
H2O: Soluble
<1mg/ml refers to the product slightly soluble or insoluble
<1mg/ml refers to the product slightly soluble or insoluble
Preparation and Storage
Powder: -20 degree C for 3 years
In solvent: -80 degree C for 2 years
In solvent: -80 degree C for 2 years
Structure
(Cefoperazone dihydrate, CAS 113826-44-1)
Structure
(Cefoperazone dihydrate, CAS 113826-44-1)
Structure
(Cefoperazone dihydrate, CAS 113826-44-1)
Structure
(Cefoperazone dihydrate, CAS 113826-44-1)
Related Product Information for alpha-Conotoxin ImI (trifluoroacetate salt) biochemical
alpha-Conotoxin ImI is a conotoxin that has been found inC. imperialisand has receptor antagonist and anticancer activities.1It is a peptide antagonist of homomeric alpha7 nicotinic acetylcholine receptors (nAChRs; IC50= 220 nM). alpha-Conotoxin ImI is selective for alpha7 nAChRs over alpha2beta2, alpha3beta2, alpha4beta2, alpha2beta4, alpha3beta4, alpha4beta4, and alpha1beta1gammadelta subunit-containing nAChRs at 5 uM but does inhibit homomeric alpha9 nAChRs (IC50= 1,800 nM). Administration of paclitaxel in micelles containing alpha-conotoxin ImI decreases tumor growth in an MCF-7 mouse xenograft model.2Intracerebroventricular, but not intraperitoneal, administration of alpha-conotoxin ImI (20 nmol/animal) induces seizures in rats.3
References
1. N Matsubara, et al. In vitro antibacterial activity of cefoperazone (T-1551), a new semisynthetic cephalosporin. Antimicrob Agents Chemother. 1979 Dec;16(6):731-5.
2. Pedro H.Di Rocco, et al. Aerosol treatment with cefoperazone or gentamicin protects granulocytopenic mice from acute Pseudomonas aeruginosa pneumonia. European Journal of Pharmaceutical Sciences Volume 1, Issue 6, June 1994, Pages 285-289.
2. Pedro H.Di Rocco, et al. Aerosol treatment with cefoperazone or gentamicin protects granulocytopenic mice from acute Pseudomonas aeruginosa pneumonia. European Journal of Pharmaceutical Sciences Volume 1, Issue 6, June 1994, Pages 285-289.
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Product Notes
The alpha-Conotoxin ImI (trifluoroacetate salt) (Catalog #AAA227022) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "alpha-Conotoxin ImI (trifluoroacetate salt), Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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