Structure
(MP-PEG4-VK(Boc)G-OSu, CAS 2378428-21-6)
NCT-501 hydrochloride Biochemical | NCT-501 biochemical
NCT-501 hydrochloride
Purity
98%
Synonyms
NCT-501 hydrochloride; N/A; NCT-501 biochemical
Purity/Purification
98%
CAS
2080306-22-3
Targets&IC50
hALDH1A1:40 nM (IC50)
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
In vitro
NCT-501 (100 ug/animal; i.t.; every alternate day for 20 days) shows a 78% inhibition in tumor growth in Cal-27 CisR derived xenografts[1].
Preparation and Storage
Powder: -20 degree C for 3 years
In solvent: -80 degree C for 2 years
In solvent: -80 degree C for 2 years
Structure
(MP-PEG4-VK(Boc)G-OSu, CAS 2378428-21-6)
Structure
(MP-PEG4-VK(Boc)G-OSu, CAS 2378428-21-6)
Structure
(MP-PEG4-VK(Boc)G-OSu, CAS 2378428-21-6)
Structure
(MP-PEG4-VK(Boc)G-OSu, CAS 2378428-21-6)
Related Product Information for NCT-501 biochemical
NCT-501 hydrochloride is a potent and selective theophylline-based inhibitor of aldehyde dehydrogenase 1A1 (ALDH1A1), inhibits hALDH1A1 with IC 50 of 40 nM, typically shows better selectivity over other ALDH isozymes and other dehydrogenases (hALDH1B1, hALDH3A1, and hALDH2, IC 50 57 uM).
References
1. Jeffrey S, et, al. Camptothecin peptide conjugates. WO2019195665A1.
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Product Notes
The NCT-501 (Catalog #AAA228077) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "NCT-501 hydrochloride, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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