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Bioactivity
(Detects Human CD47/MER6(CC-90002) in indirect ELISAs.)
CD47/MER6 recombinant protein
Recombinant Human CD47/MER6, C-His
Gene Names
CD47; IAP; OA3; MER6
Applications
ELISA, Western Blot, SDS-Page
Purity
>90% as determined by SDS-PAGE
Synonyms
CD47/MER6; N/A; Recombinant Human CD47/MER6, C-His; Leukocyte surface antigen CD47; CD47; Antigenic surface determinant protein OA3; IAP; Integrin-associated protein; Protein MER6; MER6; Drug Target; CD47/MER6 recombinant protein
Host
Mammalian cells
Purity/Purification
>90% as determined by SDS-PAGE
Form/Format
Lyophilized from a solution in PBS pH7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Sequence Positions
Met1-Glu141
Sequence Length
Met1-Glu141
Applicable Applications for CD47/MER6 recombinant protein
ELISA, WB (Western Blot), SDS-PAGE
Species
Human
Reconstitution
Reconstitute in sterile water for a stock solution.
Preparation and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 degree C for one week. Store at -20 to -80 degree C for twelve months from the date of receipt.
Bioactivity
(Detects Human CD47/MER6(CC-90002) in indirect ELISAs.)
Bioactivity
(Detects Human CD47/MER6(CC-90002) in indirect ELISAs.)
Bioactivity
(Detects Ligufalimab in indirect ELISAs.)
Bioactivity
(Detects Ligufalimab in indirect ELISAs.)
Bioactivity
(Detects Human CD47/MER6 Antibody (B6H12) in indirect ELISAs.)
Bioactivity
(Detects Human CD47/MER6 Antibody (B6H12) in indirect ELISAs.)
Bioactivity
(Detects Lemzoparlimab in indirect ELISAs.)
Bioactivity
(Detects Lemzoparlimab in indirect ELISAs.)
SDS-PAGE
(SDS PAGE for recombinant Human CD47 / MER6)
SDS-PAGE
(SDS PAGE for recombinant Human CD47 / MER6)
Product Categories/Family for CD47/MER6 recombinant protein
References
The CD47-SIRPalpha Immune Checkpoint. PMID: 32433947
Advances in Anti-Tumor Treatments Targeting the CD47/SIRPalpha Axis. PMID: 32082311
The CD47-SIRPalpha signaling axis as an innate immune checkpoint in cancer. PMID: 28258703
CD47: role in the immune system and application to cancer therapy. PMID: 31485984
CD47: the next checkpoint target for cancer immunotherapy. PMID: 32535479
Advances in Anti-Tumor Treatments Targeting the CD47/SIRPalpha Axis. PMID: 32082311
The CD47-SIRPalpha signaling axis as an innate immune checkpoint in cancer. PMID: 28258703
CD47: role in the immune system and application to cancer therapy. PMID: 31485984
CD47: the next checkpoint target for cancer immunotherapy. PMID: 32535479
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
323
NCBI Official Full Name
Leukocyte surface antigen CD47
NCBI Official Synonym Full Names
CD47 molecule
NCBI Official Symbol
CD47
NCBI Official Synonym Symbols
IAP; OA3; MER6
NCBI Protein Information
leukocyte surface antigen CD47; CD47 glycoprotein; Rh-related antigen; integrin associated protein; integrin-associated protein; integrin-associated signal transducer; antigenic surface determinant protein OA3; antigen identified by monoclonal antibody 1D
UniProt Protein Name
Leukocyte surface antigen CD47
UniProt Gene Name
CD47
UniProt Synonym Gene Names
MER6; IAP
UniProt Entry Name
CD47_HUMAN
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Product Notes
The CD47/MER6 cd47 (Catalog #AAA120498) is a Recombinant Protein produced from Mammalian cells and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is Met1-Glu141. AAA Biotech's CD47/MER6 can be used in a range of immunoassay formats including, but not limited to, ELISA, WB (Western Blot), SDS-PAGE. Researchers should empirically determine the suitability of the CD47/MER6 cd47 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD47/MER6, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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