SDS-PAGE
(Figure 1. Human CTLA-4 Protein, mFc-His Tag on SDS-PAGE under reducing condition.)
CTLA-4 recombinant protein
Recombinant human CTLA-4 protein with C-terminal mouse Fc and 6xHis tag
Gene Names
CTLA4; CD; GSE; GRD4; CD152; CTLA-4; IDDM12; CELIAC3
Applications
ELISA, Western Blot
Purity
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Synonyms
CTLA-4; N/A; Recombinant human CTLA-4 protein with C-terminal mouse Fc and 6xHis tag; Human CTLA-4 Protein, mFc-His Tag; CTLA4; CD152; CTLA-4 recombinant protein
Host
HEK293 cells
Purity/Purification
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Form/Format
Lyophilized from sterile PBS, pH 7.4. Normally 5%-24% trehalose is added as protectants before lyophilization.
Sequence
CTLA-4(Gln36-Ser161)+mFc(Pro99-Lys330)
Applicable Applications for CTLA-4 recombinant protein
ELISA, WB (Western Blot)
Source
Human
Conjugation
C-Mouse Fc and 6xHis tag
Reconstitution
Reconstitute with deionized water
Preparation and Storage
Store at -80 degree C for 12 months (Avoid repeated freezing and thawing)
Shipping: Blue Ice
Shipping: Blue Ice
SDS-PAGE
(Figure 1. Human CTLA-4 Protein, mFc-His Tag on SDS-PAGE under reducing condition.)
SDS-PAGE
(Figure 1. Human CTLA-4 Protein, mFc-His Tag on SDS-PAGE under reducing condition.)
ELISA
(Figure 1. Human CTLA-4 Protein, mFc-His Tag on SDS-PAGE under reducing condition.)
ELISA
(Figure 1. Human CTLA-4 Protein, mFc-His Tag on SDS-PAGE under reducing condition.)
Related Product Information for CTLA-4 recombinant protein
This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
24,656 Da
NCBI Official Full Name
Cytotoxic T-lymphocyte protein 4
NCBI Official Synonym Full Names
cytotoxic T-lymphocyte-associated protein 4
NCBI Official Symbol
CTLA4
NCBI Official Synonym Symbols
CD; GSE; GRD4; CD152; CTLA-4; IDDM12; CELIAC3
NCBI Protein Information
cytotoxic T-lymphocyte protein 4; CD152 isoform; celiac disease 3; cytotoxic T-lymphocyte antigen 4; insulin-dependent diabetes mellitus 12; cytotoxic T-lymphocyte-associated antigen 4; cytotoxic T-lymphocyte-associated serine esterase-4; cytotoxic T lymp
UniProt Protein Name
Cytotoxic T-lymphocyte protein 4
UniProt Gene Name
CTLA4
UniProt Synonym Gene Names
CD152; CTLA-4
UniProt Entry Name
CTLA4_HUMAN
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Product Notes
The CTLA-4 ctla4 (Catalog #AAA47199) is a Recombinant Protein produced from HEK293 cells and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's CTLA-4 can be used in a range of immunoassay formats including, but not limited to, ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the CTLA-4 ctla4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: CTLA-4(Gln 36-Ser161) +mFc(Pro99 -Lys330). It is sometimes possible for the material contained within the vial of "CTLA-4, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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