Related Product Information for LTA elisa kit
Background: Lipoteichoic acid (LTA) is a major component of the cell wall in bacteria that are gram-positive. These bacteria contain an inner "cytoplasmic" membrane and, outside it, a thick layer of peptidoglycan (as much as 80 nanometers). The structure of LTA is different depending on the species of Gram-positive bacteria and may have long chains of ribitol or glycerol phosphate. LTA is affixed to the cell membrane via a diacylglycerol and acts as regulator of autolytic wall enzymes known as muramidases. LTA can have immunogenic properties like other antigens and are able to stimulate specific immune responses. LTA from bacteria may bind to target mammalian cells either through membrane phospholipids, or to specific proteins such as CD14 and Toll-like receptors. Binding to TLR-2 has shown to induce expression of the transcription factor NF-kappaB, which results in increasing expression of both activating and inhibiting apoptotic genes. Activation of NF-kappaB also stimulates activation of mitogen-activated protein kinases (MAPK) as well as phosphoinositide 3-kinase (PI3K). The LTA ELISA Kit provides a quick and convenient system to measure LTA from mammalian serum, plasma, cell, or tissue samples; it provides sufficient reagents for up to 96 tests in a 96-well plate including standard curve and unknown samples. Detection sensitivity is 15.6 ng/mL.
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Product Notes
The LTA (Catalog #AAA44686) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "LTA (Lipoteichoic Acid), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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