Mouse Alpha-1-antichymotrypsin Monoclonal Antibody | anti-SERPINA3 antibody
Alpha-1-Antichymotrypsin Monoclonal Antibody
Gene Names
SERPINA3; ACT; AACT; GIG24; GIG25; MGC88254
Applications
ELISA
Synonyms
Alpha-1-antichymotrypsin, Antibody; Alpha-1-Antichymotrypsin Monoclonal Antibody; Anti-Alpha-1-antichymotrypsin; Alpha-1-Anti-Chymotrypsin; anti-SERPINA3 antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG2a
Specificity
These antibodies specifically recognize alpha-1-antichymotrypsin.They do not cross-react with alpha-1-antitrypsin.
Form/Format
Protein G-purified antibody in PBS, pH 7.4.
Concentration
1.1 mg/mL (varies by lot)
Applicable Applications for anti-SERPINA3 antibody
ELISA
Antigen
Purified human serum alpha-1-antichymotrypsin.
Appearance
Clear Liquid
Preparation and Storage
These antibodies are stable for one (1) year at -20°C to -70°C. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles.
Related Product Information for anti-SERPINA3 antibody
Alpha 1-antichymotrypsin (?1AC) is an alpha globulin glycoprotein produced in the liver that is a member of the serpin superfamily. In humans, it is encoded by the SERPINA3 gene. ?1AC inhibits the activity of proteases such as cathepsin G from neutrophils and chymases from mast cells by cleaving them into different conformations. This activity protects tissues, such as the lower respiratory tract, from damage caused by proteolytic enzymes. ?1AC is an acute phase protein that is induced during inflammation. Deficiency of this protein has been associated with liver disease, and mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease. It is also associated with the pathogenesis of Alzheimer's disease as it enhances the formation of amyloid-fibrils.
Product Categories/Family for anti-SERPINA3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
alpha-1-antichymotrypsin
NCBI Official Synonym Full Names
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
NCBI Official Symbol
SERPINA3
NCBI Official Synonym Symbols
ACT; AACT; GIG24; GIG25; MGC88254
NCBI Protein Information
alpha-1-antichymotrypsin; serpin A3; OTTHUMP00000028439; growth-inhibiting protein 24; growth-inhibiting protein 25; cell growth-inhibiting gene 24/25 protein; serine (or cysteine) proteinase inhibitor, clade A, member 3
UniProt Protein Name
Alpha-1-antichymotrypsin
UniProt Gene Name
SERPINA3
UniProt Synonym Gene Names
AACT
UniProt Entry Name
AACT_HUMAN
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Product Notes
The SERPINA3 serpina3 (Catalog #AAA47633) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Alpha-1-antichymotrypsin can be used in a range of immunoassay formats including, but not limited to, ELISA. Researchers should empirically determine the suitability of the SERPINA3 serpina3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Alpha-1-antichymotrypsin, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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