Mouse APP Monoclonal Antibody | anti-APP antibody

Mouse anti- Human APP monoclonal Antibody

Cat. Num. AAA118932

• Gene Names: APP; AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; CTFgamma
• Reactivity: Human. Other species are not tested. Please decide the specificity by human APP
• Applications: Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
• Purity: >95%, Protein G Purified
• Synonyms: APP, Antibody; Mouse anti- Human APP monoclonal Antibody; Amyloid Beta (A4) Precursor Protein ABPP APP Beta-Amyloid Peptide; anti-APP antibody

• Host: Mouse
• Reactivity: Human. Other species are not tested. Please decide the specificity by human APP
• Clonality: Monoclonal
• Specificity: Specific for human APP denatured and native forms.
• Purity/Purification: >95%, Protein G Purified
• Sequence Length: 770

• Applicable Applications for anti-APP antibody: IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
• Storage Buffer: Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
• Conjugate: Non-conjugated
• Immunogen: Recombinant Human APP Protein
• Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-53822 / sc-32277 / sc-58508 / sc-28365 / sc-65642
• Preparation and Storage: Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

IF (Immunofluorescence)

(Immunofluorescent analysis of HepG2 cells using AAA118932 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))

IF (Immunofluorescence)

(Immunofluorescent analysis of Hela cells using AAA118932 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))

IHC (Immunohistochemisry)

(Immunohistochemistry of paraffin-embedded human brain tissue using AAA118932 at dilution of 1:100)

IHC (Immunohiostchemistry)

(Immunohistochemistry of paraffin-embedded human testis tissue using AAA118932 at dilution of 1:100)

WB (Western Blot)

(Western blotAll lanes: Amyloid beta A4 antibody at 1ug/mlLane 1: Mouse heart tissueLane 2: Mouse kidney tissueLane 3: Mouse lung tissueSecondaryGoat polyclonal to Rabbit IgG at 1/15000 dilutionPredicted band size: 30,35,72,80 kDaObserved band size: 30,35,72 kDa)

Related Product Information for anti-APP antibody

This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.

NCBI and Uniprot Product Information

• NCBI GI #: 4502167
• NCBI GeneID: 351
• NCBI Accession #: NP_000475.1
• NCBI GenBank Nucleotide #: NM_000484.3
• UniProt Accession #: P05067; P09000; P78438; Q13764; Q13778; Q13793; Q16011; B2R5V1; B4DII8; D3DSD1; D3DSD2; D3DSD3
• Molecular Weight: 84,521 Da
• NCBI Official Full Name: amyloid beta A4 protein isoform a
• NCBI Official Synonym Full Names: amyloid beta precursor protein
• NCBI Official Symbol: APP
• NCBI Official Synonym Symbols: AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; CTFgamma
• NCBI Protein Information: amyloid beta A4 protein
• UniProt Protein Name: Amyloid beta A4 protein
• UniProt Gene Name: APP
• UniProt Synonym Gene Names: A4; AD1; APP; CVAP; PN-II; S-APP-alpha; S-APP-beta; AICD-59; AID(59); AICD-57; AID(57); AICD-50; AID(50)
• UniProt Entry Name: A4_HUMAN