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product-image-AAA39503_IF10.gif IF (Immunofluorescence) (Immunofluorescence of ASAH1 in rat heart tissue with ASAH1 antibody at 20 μg/mL.Green: APP Antibody (AAA39503)Blue: DAPI staining)

Rabbit APP Polyclonal Antibody | anti-APP antibody

APP Antibody

Gene Names
APP; AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; CTFgamma
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
APP Antibody is affinity chromatography purified via peptide column.
Synonyms
APP, Antibody; APP Antibody; APP; AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; CTFgamma; A4; Amyloid beta A4 protein; amyloid beta (A4) precursor protein; anti-APP antibody
Ordering
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
APP Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
APP Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration
1 mg/mL (varies by lot)
Sequence Length
751
Applicable Applications for anti-APP antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Immunogen
APP antibody was raised against a peptide corresponding to 10 amino acids of human amyloid A4 protein precursor (APP) corresponding to the amino terminus of the 4K Ab peptide generated by beta- and gamma-secretases.
The immunogen is located within amino acids 650-700 of APP
Homology
Predicted species reactivity based on immunogen sequence: Bovine (100%), Sheep (100%), Rabbit (100%), Guinea Pig (100%), Pig (100%)
Preparation and Storage
APP antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of ASAH1 in rat heart tissue with ASAH1 antibody at 20 μg/mL.Green: APP Antibody (AAA39503)Blue: DAPI staining)

product-image-AAA39503_IF10.gif IF (Immunofluorescence) (Immunofluorescence of ASAH1 in rat heart tissue with ASAH1 antibody at 20 μg/mL.Green: APP Antibody (AAA39503)Blue: DAPI staining)

IHC (Immunohistochemisry)

(Immunohistochemistry of APP in human brain tissue with APP antibody at 2.5 μg/ml.)

product-image-AAA39503_IHC11.gif IHC (Immunohistochemisry) (Immunohistochemistry of APP in human brain tissue with APP antibody at 2.5 μg/ml.)

IHC (Immunohiostchemistry)

(Immunohistochemistry of APP in human brain (Alzheimer's disease) tissue with APP antibody at 10 μg/mL.)

product-image-AAA39503_IHC13.jpg IHC (Immunohiostchemistry) (Immunohistochemistry of APP in human brain (Alzheimer's disease) tissue with APP antibody at 10 μg/mL.)

WB (Western Blot)

(Western blot analysis of APP in (A) human, (B) mouse, and (C) rat brain tissue lysates with APP antibody at 1 μg/mL.)

product-image-AAA39503_WB15.jpg WB (Western Blot) (Western blot analysis of APP in (A) human, (B) mouse, and (C) rat brain tissue lysates with APP antibody at 1 μg/mL.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
351
Molecular Weight
Predicted: 83 kDa
Observed: 115 kDa
NCBI Official Full Name
amyloid A4 protein
NCBI Official Synonym Full Names
amyloid beta (A4) precursor protein
NCBI Official Symbol
APP
NCBI Official Synonym Symbols
AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; CTFgamma
NCBI Protein Information
amyloid beta A4 protein; preA4; protease nexin-II; peptidase nexin-II; beta-amyloid peptide; beta-amyloid peptide(1-40); beta-amyloid peptide(1-42); alzheimer disease amyloid protein; cerebral vascular amyloid peptide
UniProt Protein Name
Amyloid beta A4 protein
UniProt Gene Name
APP
UniProt Synonym Gene Names
A4; AD1; APP; CVAP; PN-II; S-APP-alpha; S-APP-beta; AICD-59; AID(59); AICD-57; AID(57); AICD-50; AID(50)
UniProt Entry Name
A4_HUMAN

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Product Notes

The APP app (Catalog #AAA39503) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The APP Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's APP can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the APP app for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "APP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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