ICC (Immunocytochemistry)
(ICC staining Bcl10 in SW480 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)
Rabbit anti-Human BCL10 Monoclonal Antibody | anti-BCL10 antibody
BCL10 Antibody
Gene Names
BCL10; CLAP; mE10; CIPER; c-E10; CARMEN
Reactivity
Human
Applications
Immunoprecipitation, Immunohistochemistry, Immunofluorescence, Immunocytochemistry, Western Blot
Purity
ProA affinity purified
Synonyms
BCL10, Antibody; BCL10 Antibody; AI132454 antibody; B cell CLL/lymphoma 10 antibody; B cell lymphoma/leukemia10 antibody; B-cell CLL/lymphoma 10 antibody; B-cell leukemia/lymphoma 10 antibody; B-cell lymphoma/leukemia 10 antibody; Bcl 10 antibody; Bcl-10 antibody; Bcl10 antibody; BCL10_HUMAN antibody; c E10 antibody; c-E10 antibody; C81403 antibody; CARD containing apoptotic signaling protein antibody; CARD containing molecule enhancing NF kappa B antibody; CARD containing molecule enhancing NF kB antibody; CARD containing molecule enhancing NF-kB antibody; CARD containing molecule enhancing NFkB antibody; CARD containing proapoptotic protein antibody; CARD like apoptotic protein antibody; CARD-containing apoptotic signaling protein antibody; CARD-containing molecule enhancing NF-kappa-B antibody; CARD-containing proapoptotic protein antibody; CARD-like apoptotic protein antibody; CARMEN antibody; Caspase recruiting domain containing protein antibody; caspase-recruiting domain-containing protein antibody; cCARMEN antibody; cE 10 antibody; cE10 antibody; CED 3/ICH 1 prodomain homologous E10 like regulator antibody; CED-3/ICH-1 prodomain homologous E10-like regulator antibody; CED3/ICH1 prodomain homologous E10 like regulator antibody; Cellular E10 antibody; Cellular homolog of vCARMEN antibody; Cellular-E10 antibody; CIPER antibody; CLAP antibody; hCLAP antibody; Mammalian CARD containing adapter molecule E10 antibody; Mammalian CARD-containing adapter molecule E10 antibody; mE 10 antibody; mE10 antibody; R-RCD1 antibody; anti-BCL10 antibody
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Clone Number
SN74-04
Purity/Purification
ProA affinity purified
Form/Format
1*TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Applicable Applications for anti-BCL10 antibody
IP (Immunoprecipitation), IHC (Immunohistochemistry), IF (Immunofluorescence), ICC (Immunocytochemistry), WB (Western Blot)
Antibody Type
Recombinant Antibody
Immunogen
Recombinant protein
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C.
ICC (Immunocytochemistry)
(ICC staining Bcl10 in SW480 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)
ICC (Immunocytochemistry)
(ICC staining Bcl10 in SW480 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)
ICC (Immunocytochemistry)
(ICC staining Bcl10 in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)
ICC (Immunocytochemistry)
(ICC staining Bcl10 in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)
IHC (Immunohistochemistry)
(Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Bcl10 antibody. Counter stained with hematoxylin.)
IHC (Immunohistochemistry)
(Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Bcl10 antibody. Counter stained with hematoxylin.)
Related Product Information for anti-BCL10 antibody
Bcl10, also designated CIPER, c-CARMEN and mE10, was first identified as a gene truncated or mutated in MALT B cell lymphomas and other tumor types. Bcl10 is homologous to the equine herpesvirus-2 E10 gene and, like E10, it contains an N-terminal caspase recruitment domain (CARD). Expression of Bcl10 has been shown to induce NFκB activation in a NIK-dependent pathway, and research indicates that the CARD domain is essential for this activation; although in a separate study, Bcl10 by itself did not induce JNK or NFκB activation. Overexpression of Bcl10 has been shown to induce apoptosis in a manner dependent on CARD-mediated oligomerization. Bcl10 has also been shown to play a role in processing of caspase-9 to its active dimer. Other studies have shown that Bcl10 is not mutated in many human tumors and lymphomas.
Product Categories/Family for anti-BCL10 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
26,252 Da
NCBI Official Full Name
B-cell lymphoma/leukemia 10
NCBI Official Synonym Full Names
B-cell CLL/lymphoma 10
NCBI Official Symbol
BCL10
NCBI Official Synonym Symbols
CLAP; mE10; CIPER; c-E10; CARMEN
NCBI Protein Information
B-cell lymphoma/leukemia 10; hCLAP; cCARMEN; cellular-E10; cellular homolog of vCARMEN; CARD-containing proapoptotic protein; CARD containing molecule enhancing NF-kB; CARD-containing apoptotic signaling protein; caspase-recruiting domain-containing prote
UniProt Protein Name
B-cell lymphoma/leukemia 10
UniProt Gene Name
BCL10
UniProt Synonym Gene Names
CIPER; CLAP; Bcl-10; hCLAP; CIPER; cCARMEN; c-E10; mE10
UniProt Entry Name
BCL10_HUMAN
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Product Notes
The BCL10 bcl10 (Catalog #AAA312306) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The BCL10 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's BCL10 can be used in a range of immunoassay formats including, but not limited to, IP (Immunoprecipitation), IHC (Immunohistochemistry), IF (Immunofluorescence), ICC (Immunocytochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the BCL10 bcl10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BCL10, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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