Mouse anti-Human CD143 Monoclonal Antibody | anti-CD143 antibody
Anti-Hu CD143 Purified
Gene Names
ACE; DCP; ACE1; DCP1; CD143
Reactivity
Human
Applications
Flow Cytometry, Functional Assay
Purity
Purified by Protein-A Affinity Chromatography
Synonyms
CD143, Antibody; Anti-Hu CD143 Purified; angiotensin I converting enzyme; DCP; ACE1; DCP1; carboxycathepsin; kininase II; peptidase P; peptidyl dipeptidase 1; anti-CD143 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
5-369
Specificity
The mouse monoclonal antibody 5-369 recognizes an extracellular epitope of CD143, a 171 kDa type I transmembrane glycoprotein with metallopeptidase activity, expressed mainly on endothelial cells.
Purity/Purification
Purified by Protein-A Affinity Chromatography
Form/Format
Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Concentration
1 mg/ml (varies by lot)
Sequence Length
32
Applicable Applications for anti-CD143 antibody
FCM/FACS (Flow Cytometry)
Immunogen
dendritic cells
Preparation and Storage
Store at 2-8 degree C.
Related Product Information for anti-CD143 antibody
CD143, also known as ACE (angiotensin-converting enzyme), carboxycathepsin, kininase II, peptidase P, or peptidyl dipeptidase 1, is a transmembrane zinc metallopeptidase catalyzing the conversion of angiotensin I into the physiologically active angiotensin II, which is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, that are equally active. CD143 is expressed mainly on endothelial cells, but it can be found also e.g. on activated macrophages and histiocytes.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
NCBI Official Full Name
angiotensin I converting enzyme, partial
NCBI Official Synonym Full Names
angiotensin I converting enzyme
NCBI Official Symbol
ACE
NCBI Official Synonym Symbols
DCP; ACE1; DCP1; CD143
NCBI Protein Information
angiotensin-converting enzyme
UniProt Protein Name
Angiotensin-converting enzyme
UniProt Gene Name
ACE
UniProt Synonym Gene Names
DCP; DCP1; ACE
UniProt Entry Name
ACE_HUMAN
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Product Notes
The CD143 ace (Catalog #AAA128369) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-Hu CD143 Purified reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CD143 can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry). Researchers should empirically determine the suitability of the CD143 ace for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD143, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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