anti-Mouse CD81/TAPA-1 Monoclonal Antibody | anti-CD81 antibody
Hamster Anti-Mouse CD81-LE/AF
Gene Names
CD81; S5.7; CVID6; TAPA1; TSPAN28
Reactivity
Mouse
Applications
Flow Cytometry, Functional Assay
Synonyms
CD81/TAPA-1, Antibody; Hamster Anti-Mouse CD81-LE/AF; Hamster Anti-Mouse CD81 - Low Endotoxin/Azide-Free; Hamster Anti-Mouse CD81/TAPA-1; anti-CD81 antibody
Host
Armenian Hamster
Reactivity
Mouse
Clonality
Monoclonal
Isotype
Hamster (Armenian) IgG3
Clone Number
2F7
Specificity
Mouse CD81; Mr 26 kDa
Form/Format
The low endotoxin, azide-free (LE/AF) antibody is supplied as 0.5 mg purified immunoglobulin in 1.0 mL of PBS. Contains no preservative; handle under aseptic conditions.
Sequence Length
236
Applicable Applications for anti-CD81 antibody
FCM/FACS (Flow Cytometry)
Immunogen
Mouse epithelial cell line PAM212
Preparation and Storage
Store at 2-8°C or aliquot into smaller volumes and store at -20°C. Avoid multiple freeze / thaw cycles
Related Product Information for anti-CD81 antibody
Description: CD81, also known as TAPA-1, is an integral membrane protein expressed on a variety of cell types and has a high degree of sequence homology between human and mouse. CD81 is expressed on thymic stromal cells where it plays an important role in the transition of γδ+ T cells to more mature T cells with αβ T cell receptors. Immunohistochemical staining has revealed that its expression is localized to the subcapsular region of the thymus and, specifically, on cells that have distinct clustering patterns. It has been speculated that the ligand for CD81 is the pre-T cell receptor which is composed of a TCR β chain and glycoprotein pTα. The monoclonal antibody 2F7 can block thymocyte interaction with CD81 in vitro.
References
1. Andria, M.L., et al. 1991. J. Immunol. 147:1030.
2. Boismenu, R., M. Rhein, W.H. Fischer, and W.L. Harven. 1996. Science 271:198.
2. Boismenu, R., M. Rhein, W.H. Fischer, and W.L. Harven. 1996. Science 271:198.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
CD81 antigen
NCBI Official Synonym Full Names
CD81 molecule
NCBI Official Symbol
CD81
NCBI Official Synonym Symbols
S5.7; CVID6; TAPA1; TSPAN28
NCBI Protein Information
CD81 antigen; tspan-28; tetraspanin-28; OTTHUMP00000011528; OTTHUMP00000011529; OTTHUMP00000229004; OTTHUMP00000229005; OTTHUMP00000229006; OTTHUMP00000229008; OTTHUMP00000229358; OTTHUMP00000229392; 26 kDa cell surface protein TAPA-1; CD81 antigen (target of antiproliferative antibody 1)
UniProt Protein Name
CD81 antigen
UniProt Gene Name
CD81
UniProt Synonym Gene Names
TAPA1; TSPAN28
UniProt Entry Name
CD81_HUMAN
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Product Notes
The CD81 cd81 (Catalog #AAA78684) is an Antibody produced from Armenian Hamster and is intended for research purposes only. The product is available for immediate purchase. The Hamster Anti-Mouse CD81-LE/AF reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CD81/TAPA-1 can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry). Researchers should empirically determine the suitability of the CD81 cd81 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD81/TAPA-1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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