Mouse CD81/TAPA-1 Monoclonal Antibody | anti-CD81 antibody

CD81/TAPA-1

Cat. Num. AAA215437

• Gene Names: CD81; S5.7; CVID6; TAPA1; TSPAN28
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, Immunohistochemistry, Immunofluorescence, Flow Cytometry, Functional Assay
• Purity: Purified Ab with BSA and Azide at 200ug/ml or Purified Ab with BSA and Azide at 200ug/ml or Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
• Synonyms: CD81/TAPA-1, Antibody; CD81/TAPA-1; CD81; Target of the antiproliferative antibody 1 (TAPA-1); Tetraspanin-28; Tspan-28; anti-CD81 antibody

• Host: Mouse
• Reactivity: Human, Mouse, Rat
• Clonality: Monoclonal
• Isotype: IgG1, kappa
• Clone Number: r1.3.3.22
• Specificity: Recognizes a protein of 26kDa, identified as CD81 (Workshop VI; Code CD81.1)). CD81 has a very broad cellular distribution, being expressed on T- and B-lymphocytes, NK cells, thymocytes, eosinophils, fibroblasts, epithelial and endothelial cells. Neutrophils, erythrocytes and platelets are negative, while monocytes are variably positive. CD81 is a member of a family of tetraspans transmembrane proteins, including CD9, CD37, CD53, CD63, and CD82. It associates with CD19, CD21, Leu 13, and integrins on cell membrane and is involved in signal transduction in B lymphocyte development and cell adhesion. CD81 also acts as a receptor for the envelope protein E2 of chronic hepatitis C virus. Antibodies to CD81 have anti-proliferative effects on different lymphoid cell lines, particularly those derived from large cell lymphomas.
• Purity/Purification: Purified Ab with BSA and Azide at 200ug/ml or Purified Ab with BSA and Azide at 200ug/ml or Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
• Form/Format: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
• Sequence Length: 236

• Applicable Applications for anti-CD81 antibody: WB (Western Blot), IHC (Immunohistochemistry), IF (Immunofluorescence), FCM/FACS (Flow Cytometry)
• Immunogen: Recombinant full-length Human CD81 protein
• Cellular Localization: Cell Surface
• Antibody Type: Recombinant Antibody
• Hu-chromosome Location: 11p15.5
• Positive Control: Ramos, Daudi or Jurkat cells. Human lymphocytes. Human Tonsil or liver.
• Preparation and Storage: Antibody with azide: store at 2 to 8 degree C.; Antibody without azide: store at -20 to -80 degree C.; Antibody is stable for 24 months. Non-hazardous. No MSDS required.

IHC (Immunohiostchemistry)

(Formalin-fixed, paraffin-embedded human tonsil stained with CD81 Recombinant Mouse Monoclonal Antibody (r1.3.3.22).)

IHC (Immunohistochemistry)

(Formalin-fixed, paraffin-embedded human tonsil stained with CD81 Recombinant Mouse Monoclonal Antibody (r1.3.3.22).)

References

Kishimoto T et al. eds. Leukocyte Typing VI, p187-189, Garland Publishing, New York, 1997. | Takahashi S et al. J Immunol 1990, 145(7):2207-2213.

NCBI and Uniprot Product Information

• NCBI GI #: 38503376
• NCBI GeneID: 975
• UniProt Accession #: P60033
• Molecular Weight: 26kDa
• NCBI Official Full Name: CD81 antigen
• NCBI Official Synonym Full Names: CD81 molecule
• NCBI Official Symbol: CD81
• NCBI Official Synonym Symbols: S5.7; CVID6; TAPA1; TSPAN28
• NCBI Protein Information: CD81 antigen
• UniProt Protein Name: CD81 antigen
• UniProt Gene Name: CD81
• UniProt Synonym Gene Names: TAPA1; TSPAN28; Tspan-28