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product-image-AAA29399_APP6.jpg Application Data (10C12 inhibited the tumor growth of COLO205 on nude mice. The result showed significant anti-tumor effects, with an tumor inhibition rate (TGI) of 70.0% at 5 mpk at D26.)

CDH17/Cadherin-17 Recombinant Antibody | CDH17 recombinant antibody

Anti-CDH17/Cadherin-17 Reference Antibody (10C12)

Gene Names
CDH17; HPT1; CDH16; HPT-1
Reactivity
Human
Applications
ELISA, Flow Cytometry, Functional Assay, Functional Assay
Synonyms
CDH17/Cadherin-17, Recombinant Antibody; Anti-CDH17/Cadherin-17 Reference Antibody (10C12); CDH17 recombinant antibody
Ordering
For Research Use Only!
Host
CHO Cell
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Specificity
CDH17/Cadherin-17
Form/Format
Purified monoclonal antibody supplied in PBS, pH6.0, without preservative.This antibody is purified through a protein A column.
Concentration
1mg/ml (varies by lot)
Applicable Applications for CDH17 recombinant antibody
ELISA (EIA), Flow Cytometry (FC/FACS), Kinetics, Functional Assay (FUNC), Animal Model
Endotoxin
< 0.001EU/ug, determined by LAL method.
Conjugation
Unconjugated
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Store at -80 degree C for 2 years under sterile conditions; -20 degree C for 1 year under sterile conditions; Avoid repeated freeze-thaw cycles.

Application Data

(10C12 inhibited the tumor growth of COLO205 on nude mice. The result showed significant anti-tumor effects, with an tumor inhibition rate (TGI) of 70.0% at 5 mpk at D26.)

product-image-AAA29399_APP6.jpg Application Data (10C12 inhibited the tumor growth of COLO205 on nude mice. The result showed significant anti-tumor effects, with an tumor inhibition rate (TGI) of 70.0% at 5 mpk at D26.)

Application Data

(The endocytosis ratio 10C12 by Human CDH17 HEK293 increased with the increase of antibody concentration, and the Internalization Rate (%) reached 80% at antibody concentration of 2 nM.)

product-image-AAA29399_APP5.jpg Application Data (The endocytosis ratio 10C12 by Human CDH17 HEK293 increased with the increase of antibody concentration, and the Internalization Rate (%) reached 80% at antibody concentration of 2 nM.)

FCM (Flow Cytometry)

(Human CDH17 HEK293 cells were stained with Anti-CDH17 / Cadherin-17 Reference Antibody (10C12) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC240=0.06889 ug/mL)

product-image-AAA29399_FCM4.jpg FCM (Flow Cytometry) (Human CDH17 HEK293 cells were stained with Anti-CDH17 / Cadherin-17 Reference Antibody (10C12) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC240=0.06889 ug/mL)

Application Data

(Immobilized human CDH17, His Tag at 2 ug/mL can bind Anti-CDH17 / Cadherin-17 Reference Antibody (10C12), EC50=0.00468ug/mL)

product-image-AAA29399_APP3.jpg Application Data (Immobilized human CDH17, His Tag at 2 ug/mL can bind Anti-CDH17 / Cadherin-17 Reference Antibody (10C12), EC50=0.00468ug/mL)

Application Data

(The purity of Anti-CDH17 / Cadherin-17 Reference Antibody (10C12)is more than 98.15% ,determined by SEC-HPLC.)

product-image-AAA29399_APP2.jpg Application Data (The purity of Anti-CDH17 / Cadherin-17 Reference Antibody (10C12)is more than 98.15% ,determined by SEC-HPLC.)

SDS-PAGE

(Anti-CDH17 / Cadherin-17 Reference Antibody (10C12) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%)

product-image-AAA29399_SDS_PAGE.jpg SDS-PAGE (Anti-CDH17 / Cadherin-17 Reference Antibody (10C12) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%)
Product Categories/Family for CDH17 recombinant antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
92,219 Da
NCBI Official Full Name
cadherin-17
NCBI Official Synonym Full Names
cadherin 17, LI cadherin (liver-intestine)
NCBI Official Symbol
CDH17
NCBI Official Synonym Symbols
HPT1; CDH16; HPT-1
NCBI Protein Information
cadherin-17; LI cadherin; LI-cadherin; cadherin-16; HPT-1 cadherin; liver-intestine cadherin; human peptide transporter 1; intestinal peptide-associated transporter HPT-1; human intestinal peptide-associated transporter HPT-1
UniProt Protein Name
Cadherin-17
UniProt Gene Name
CDH17
UniProt Synonym Gene Names
LI-cadherin
UniProt Entry Name
CAD17_HUMAN

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Product Notes

The CDH17 cdh17 (Catalog #AAA29399) is a Recombinant Antibody produced from CHO Cell and is intended for research purposes only. The product is available for immediate purchase. The Anti-CDH17/Cadherin-17 Reference Antibody (10C12) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CDH17/Cadherin-17 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Flow Cytometry (FC/FACS), Kinetics, Functional Assay (FUNC), Animal Model. Researchers should empirically determine the suitability of the CDH17 cdh17 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CDH17/Cadherin-17, Monoclonal Recombinant Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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