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Application Data
Mouse anti-Human CEACAM-1 Monoclonal Antibody | anti-CEACAM-1 antibody
Mouse Anti-Human CEACAM-1
Gene Names
CEACAM1; BGP; BGP1; BGPI
Reactivity
Human
Applications
Flow Cytometry, Functional Assay, Immunohistochemistry, Western Blot
Purity
Protein G purified
Synonyms
CEACAM-1, Antibody; Mouse Anti-Human CEACAM-1; Anti-Human CEACAM-1 (#C5-1X); Carcinoembryonic antigen-related cell adhesion molecule 1; anti-CEACAM-1 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1, kappa
Clone Number
mouse IgG1 kappa, C5-1X
Specificity
Anti-human CEACAM-1 (C5-1X) interacts solely with human CEACAM-1 and shows no cross-reactivity with other CEACAMs expressed in human or other species! C5-1X binds to the A1-B-Domain!
Purity/Purification
Protein G purified
Form/Format
Lyophilized
Sequence Length
464
Applicable Applications for anti-CEACAM-1 antibody
FCM/FACS (Flow Cytometry), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
Recombinant human sCEACAM-1/Fc lacking the N-domain
Preparation
Monoclonal antibodies were produced with the help of NS1/0 mice using recombinant human soluble CEACAM-1-Fc lacking the N-domain (produced in HEK293 cells) as the immunizing antigen.
Buffer
PBS
Preparation and Storage
The lyophilized antibody is stable at room temperature for up to 1 month. The reconstituted antibody is stable for at least two weeks at 2-8 degree C. Frozen aliquots are stable for at least 6 months when stored at -20 degree C.
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Related Product Information for anti-CEACAM-1 antibody
Carcinoembryonic Antigen-related Cell Adhesion Molecule 1 (CEACAM-1), also known as CD66a and BGP-I, is a 115 kDa type I transmembrane glycoprotein that belongs to the membrane-bound CEA subfamily of the CEA superfamily. On the surface of cells, it forms noncovalent homo- and heterodimers. The extracellular region contains three C2-type Ig-like domains and one N-terminal V-type Ig-like domain. Multiple splice variants involving regions C-terminal to the second C2-type domain (aa 320 and beyond) exist.
References
1. Muturi HT et al, PLOS/one Vol 8, Issue 9 (2013) 2. Klaile E et al, Respiratory Research 14 (2013) 3. Waggener and Ergun, Exp Cell Res 261 (2000) 4. Barnett et al, J Cell Biol 108 (1989) 5. Hinoda et al, Proc Natl Acad Sci 85 (1998) 6. Müller et al, Blood 105 (2006) 7. Kilic et al, Blood 110 (2007) 8. Zengin et al, Development 133 (2006) 9. Oliveira-Ferrer et al, Cancer Res 64 (2004);
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
57,560 Da
NCBI Official Full Name
carcinoembryonic antigen-related cell adhesion molecule 1 isoform 2
NCBI Official Synonym Full Names
carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
NCBI Official Symbol
CEACAM1
NCBI Official Synonym Symbols
BGP; BGP1; BGPI
NCBI Protein Information
carcinoembryonic antigen-related cell adhesion molecule 1; antigen CD66; CD66a antigen
UniProt Protein Name
Carcinoembryonic antigen-related cell adhesion molecule 1
UniProt Gene Name
CEACAM1
UniProt Synonym Gene Names
BGP; BGP1; BGP-1
UniProt Entry Name
CEAM1_HUMAN
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Product Notes
The CEACAM-1 ceacam1 (Catalog #AAA79100) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Anti-Human CEACAM-1 reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CEACAM-1 can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the CEACAM-1 ceacam1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CEACAM-1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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