Mouse ECD/SGT1 Monoclonal Antibody | anti-ECD antibody
ECD/SGT1 Mouse Monoclonal Antibody [Clone PCRP-ECD-1D10]
Gene Names
ECD; GCR2; HSGT1
Reactivity
HumanPredicted to react with Rabbit, Goat, Horse, Guinea pig, Dog, Pig, Rhesus monkey, Orangutan and Elephant (based on sequence homology).
Applications
Immunofluorescence, Flow Cytometry, Functional Assay, Immunoprecipitation
Synonyms
ECD/SGT1, Antibody; ECD/SGT1 Mouse Monoclonal Antibody [Clone PCRP-ECD-1D10]; Ecdysoneless homolog; hSGT1; Human suppressor of GCR two; Protein ecdysoneless homolog; SGT1 protein; anti-ECD antibody
Host
Mouse
Reactivity
Human
Predicted to react with Rabbit, Goat, Horse, Guinea pig, Dog, Pig, Rhesus monkey, Orangutan and Elephant (based on sequence homology).
Predicted to react with Rabbit, Goat, Horse, Guinea pig, Dog, Pig, Rhesus monkey, Orangutan and Elephant (based on sequence homology).
Clonality
Monoclonal
Isotype
Mouse/IgG2b
Clone Number
PCRP-ECD-1D10
Form/Format
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0. 05% BSA & 0. 05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration
Purified Ab with BSA and Azide at 200ug/ml
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
Applicable Applications for anti-ECD antibody
IF (Immunofluorescence), FCM/FACS (Flow Cytometry), IP (Immunoprecipitation)
Immunogen
Recombinant full-length human ECD protein
Cellular Localization
Nucleus, Cytosol
Positive Control
HeLa or 293T cells. Human testis, spleen or colon.
Hu-chromosome Location
10q22.2
Unigene
631822
Preparation and Storage
Antibody with azide: store at 2 to 8 degree C
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Related Product Information for anti-ECD antibody
Inhibits MDM2-mediated degradation of p53/TP53 possibly by cooperating in part with TXNIP. May be involved transcriptional regulation. In vitro has intrinsic transactivation activity enhanced by EP300. May be a transcriptional activator required for the expression of glycolytic genes. Involved in regulation of cell cycle progression. Proposed to disrupt Rb-E2F binding leading to transcriptional activation of E2F proteins. The cell cycle -regulating function may depend on its RUVBL1-mediated association with the R2TP complex. May play a role in regulation of pre-mRNA splicing.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
644
NCBI Official Full Name
Protein SGT1
NCBI Official Synonym Full Names
ecdysoneless homolog (Drosophila)
NCBI Official Symbol
ECD
NCBI Official Synonym Symbols
GCR2; HSGT1
NCBI Protein Information
protein SGT1; suppressor of GCR2; protein ecdysoneless homolog; suppressor of S. cerevisiae gcr2
UniProt Protein Name
Protein SGT1
UniProt Gene Name
ECD
UniProt Synonym Gene Names
SGT1; hSGT1
UniProt Entry Name
SGT1_HUMAN
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Product Notes
The ECD ecd (Catalog #AAA215546) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The ECD/SGT1 Mouse Monoclonal Antibody [Clone PCRP-ECD-1D10] reacts with Human Predicted to react with Rabbit, Goat, Horse, Guinea pig, Dog, Pig, Rhesus monkey, Orangutan and Elephant (based on sequence homology). and may cross-react with other species as described in the data sheet. AAA Biotech's ECD/SGT1 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), FCM/FACS (Flow Cytometry), IP (Immunoprecipitation). Researchers should empirically determine the suitability of the ECD ecd for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ECD/SGT1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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