IF (Immunofluorescence)
(Immunofluorescence of Estrogen Receptor alpha (green) in MCF-7 using Estrogen Receptor alpha antibody at dilution 1:20, and DAPI(blue))
Rabbit anti-Human Estrogen Receptor alpha Monoclonal Antibody | anti-ESR1 antibody
Recombinant Estrogen Receptor alpha Monoclonal Antibody
Gene Names
ESR1; ER; ESR; Era; ESRA; NR3A1
Reactivity
Human
Applications
Immunofluorescence, Immunohistochemistry, Western Blot
Purity
Affinity Purified
Synonyms
Estrogen Receptor alpha, Antibody; Recombinant Estrogen Receptor alpha Monoclonal Antibody; DKFZp686N23123; ER alpha; ER; ER-alpha; Era; ESR; ESR1; ESRA; Estradiol receptor; Estrogen nuclear receptor alpha; Estrogen receptor 1; Estrogen receptor alpha 3*; 4; 5; 6; 7*/822 isoform; Estrogen receptor alpha; Estrogen receptor alpha delta 3*; 7*; 8*/941 isoform; 7*/819 2 isoform; Estrogen receptor alpha delta 4 +49 isoform; Estrogen receptor alpha delta 4*; 7*/654 isoform; 7; 8*/901 isoform; Estrogen receptor alpha E1 E2 1 2; Estrogen receptor alpha E1 N2 E2 1 2; Estrogen receptor; ESTRR; NR3A1; Nuclear receptor subfamily 3 group A member 1; anti-ESR1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG
Clone Number
R05-1E4
Purity/Purification
Affinity Purified
Form/Format
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Concentration
300ug/mL (varies by lot)
Applicable Applications for anti-ESR1 antibody
IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthetic peptide of human Estrogen Receptor alpha
Research Area
Cancer, Epigenetics and Nuclear Signaling, Neuroscience, Signal Transduction
Preparation and Storage
Storage: -20 degree C/One year. Avoid freeze/thaw cycles.
IF (Immunofluorescence)
(Immunofluorescence of Estrogen Receptor alpha (green) in MCF-7 using Estrogen Receptor alpha antibody at dilution 1:20, and DAPI(blue))
IF (Immunofluorescence)
(Immunofluorescence of Estrogen Receptor alpha (green) in MCF-7 using Estrogen Receptor alpha antibody at dilution 1:20, and DAPI(blue))
IHC (Immunohiostchemistry)
(Immunohistochemistry of Estrogen Receptor alpha in paraffin-embedded Human breast cancer tissue using Estrogen Receptor alpha Rabbit mAb at dilution 1:50)
IHC (Immunohiostchemistry)
(Immunohistochemistry of Estrogen Receptor alpha in paraffin-embedded Human breast cancer tissue using Estrogen Receptor alpha Rabbit mAb at dilution 1:50)
WB (Western Blot)
(Western blot detection of Estrogen Receptor alpha in K562,Hela cell lysates using Estrogen Receptor alpha Rabbit mAb(1:1000 diluted).Predicted band size:66kDa.Observed band size:66kDa.)
WB (Western Blot)
(Western blot detection of Estrogen Receptor alpha in K562,Hela cell lysates using Estrogen Receptor alpha Rabbit mAb(1:1000 diluted).Predicted band size:66kDa.Observed band size:66kDa.)
Related Product Information for anti-ESR1 antibody
This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters.
Product Categories/Family for anti-ESR1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
66,216 Da
NCBI Official Full Name
estrogen receptor
NCBI Official Synonym Full Names
estrogen receptor 1
NCBI Official Symbol
ESR1
NCBI Official Synonym Symbols
ER; ESR; Era; ESRA; NR3A1
NCBI Protein Information
estrogen receptor; ER-alpha; estradiol receptor; estrogen nuclear receptor alpha; estrogen receptor alpha E1-E2-1-2; estrogen receptor alpha E1-N2-E2-1-2; estrogen receptor alpha delta 4 +49 isoform; nuclear receptor subfamily 3 group A member 1; estrogen
UniProt Protein Name
Estrogen receptor
UniProt Gene Name
ESR1
UniProt Synonym Gene Names
ESR; NR3A1; ER
UniProt Entry Name
ESR1_HUMAN
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Product Notes
The ESR1 esr1 (Catalog #AAA178794) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Recombinant Estrogen Receptor alpha Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Estrogen Receptor alpha can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the ESR1 esr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Estrogen Receptor alpha, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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