WB (Western Blot)
(Western blot of extracts (35 ug) from 9 different cell lines by using anti-FMR1 monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).)
Mouse FMR1 / FMRP Monoclonal Antibody | anti-FMR1 / FMRP antibody
Anti-FMR1 / FMRP Antibody (clone 1D10) IHC-plus
Gene Names
FMR1; POF; FMRP; POF1; FRAXA
Reactivity
Mouse, Dog, Rat, Human, Monkey
Applications
Western Blot, Immunohistochemistry
Purity
Protein A/G purified
Synonyms
FMR1 / FMRP, Antibody; Anti-FMR1 / FMRP Antibody (clone 1D10) IHC-plus; Mouse Monoclonal [clone 1D10] (IgG2b) to Human FMR1 / FMRP; Human FMR1 / FMRP; POF; Protein FMR-1; Premature ovarian failure 1; Fragile X mental retardation 1; FRAXA; POF1; anti-FMR1 / FMRP antibody
Host
Mouse
Reactivity
Mouse, Dog, Rat, Human, Monkey
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
1D10
Specificity
Human FMR1 / FMRP
Purity/Purification
Protein A/G purified
Form/Format
PBS, pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide
Concentration
1 mg/ml (varies by lot)
Sequence Length
632
Applicable Applications for anti-FMR1 / FMRP antibody
WB (Western Blot), IHC (Immunohistochemistry)
Immunogen
FMR1 / FMRP antibody was raised against human recombinant protein fragment corresponding to amino acids 36-279 of human FMR1(NP_002015) produced in E Coli.
Immunogen Description
Human recombinant protein fragment corresponding to amino acids 36-279 of human FMR1(NP_002015) produced in E Coli.
Immunogen Type
Recombinant protein
Target Species
Human
Preparation and Storage
Store at -20 degree C. Minimize freezing and thawing.
WB (Western Blot)
(Western blot of extracts (35 ug) from 9 different cell lines by using anti-FMR1 monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).)
WB (Western Blot)
(Western blot of extracts (35 ug) from 9 different cell lines by using anti-FMR1 monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).)
WB (Western Blot)
(HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FMR1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FMR1.)
WB (Western Blot)
(HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FMR1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FMR1.)
IHC (Immunohistochemistry)
(Anti-FMR1 / FMRP antibody IHC staining of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)
IHC (Immunohistochemistry)
(Anti-FMR1 / FMRP antibody IHC staining of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)
Related Product Information for anti-FMR1 / FMRP antibody
FMR1 Antibody, FMRP Antibody, POF Antibody, Protein FMR-1 Antibody, Premature ovarian failure 1 Antibody, Fragile X mental retardation 1 Antibody, FRAXA Antibody, POF1 Antibody Description: Translation repressor. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates translation repression (By similarity). RNA-binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs. Associated with polysomes. May play a role in the transport of mRNA from the nucleus to the cytoplasm.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
68,966 Da
NCBI Official Full Name
fragile X mental retardation protein 1 isoform ISO1
NCBI Official Synonym Full Names
fragile X mental retardation 1
NCBI Official Symbol
FMR1
NCBI Official Synonym Symbols
POF; FMRP; POF1; FRAXA
NCBI Protein Information
fragile X mental retardation protein 1
UniProt Protein Name
Fragile X mental retardation protein 1
UniProt Gene Name
FMR1
UniProt Synonym Gene Names
FMRP; Protein FMR-1
UniProt Entry Name
FMR1_HUMAN
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Product Notes
The FMR1 / FMRP fmr1 (Catalog #AAA52581) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-FMR1 / FMRP Antibody (clone 1D10) IHC-plus reacts with Mouse, Dog, Rat, Human, Monkey and may cross-react with other species as described in the data sheet. AAA Biotech's FMR1 / FMRP can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the FMR1 / FMRP fmr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FMR1 / FMRP, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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