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product-image-AAA300833_IHC10.jpg IHC (Immunohistochemistry) (Immunohistochemical analysis of paraffin-embedded Prostate Cancer using HP1-gamma Mouse mAb (1/200 dilution).Antigen retrieval was performed by pressure cooking in citrate buffer (pH 6.0).)

Mouse HP1-gamma Monoclonal Antibody | anti-HP1-gamma antibody

HP1-gamma Monoclonal Antibody

Gene Names
CBX3; HECH; HP1-GAMMA; HP1Hs-gamma
Reactivity
Mouse, Human, Monkey, Hamster, Rat
Applications
Immunohistochemistry, Immunoprecipitation, Immunocytochemistry, Western Blot
Purity
Affinity purified
Synonyms
HP1-gamma, Antibody; HP1-gamma Monoclonal Antibody; CBX 3; CBX3; CBX3_HUMAN; Chromobox homolog 3 (HP1 gamma homolog, Drosophila); Chromobox homolog 3; Chromobox protein homolog 3; GAMMA; HECH; Heterochromatin like protein 1; Heterochromatin protein 1 homolog gamma; Heterochromatin protein HP1 gamma; anti-HP1-gamma antibody
Ordering
Host
Mouse
Reactivity
Mouse, Human, Monkey, Hamster, Rat
Clonality
Monoclonal
Isotype
IgG1
Clone Number
5G10-F7-A12
Specificity
This antibody detects endogenous levels of HP1-gamma and does not cross-react with related proteins.
Purity/Purification
Affinity purified
Form/Format
Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.
Sequence Length
183
Applicable Applications for anti-HP1-gamma antibody
IHC (Immunohistochemistry), IP (Immunoprecipitation), ICC (Immunocytochemistry), WB (Western Blot)
Immunogen Type
Recombinant Protein
Immunogen Description
Purified recombinant human HP1-gamma protein fragments expressed in E Coli.
Target Name
HP1-gamma
Preparation and Storage
Store at -20 degree C

IHC (Immunohistochemistry)

(Immunohistochemical analysis of paraffin-embedded Prostate Cancer using HP1-gamma Mouse mAb (1/200 dilution).Antigen retrieval was performed by pressure cooking in citrate buffer (pH 6.0).)

product-image-AAA300833_IHC10.jpg IHC (Immunohistochemistry) (Immunohistochemical analysis of paraffin-embedded Prostate Cancer using HP1-gamma Mouse mAb (1/200 dilution).Antigen retrieval was performed by pressure cooking in citrate buffer (pH 6.0).)

IP (Immunoprecipitation)

(Immunoprecipitation analysis of Hela cell lysates using HP1-gamma antibody.)

product-image-AAA300833_IP11.jpg IP (Immunoprecipitation) (Immunoprecipitation analysis of Hela cell lysates using HP1-gamma antibody.)

WB (Western Blot)

(Western blot detection of HP1-gamma in Hela,3T3,C6,COS7 and CHO-K1 cell lysates using HP1-gamma antibody (1:1000 diluted).Predicted band size:22KDa.Observed band size:22KDa.)

product-image-AAA300833_WB13.jpg WB (Western Blot) (Western blot detection of HP1-gamma in Hela,3T3,C6,COS7 and CHO-K1 cell lysates using HP1-gamma antibody (1:1000 diluted).Predicted band size:22KDa.Observed band size:22KDa.)

ICC (Immunocytochemistry)

(Immunocytochemistry staining of HeLa cells fixed with 4% Paraformaldehyde and using anti-HP1-gamma antibody (dilution 1:200).)

product-image-AAA300833_ICC15.jpg ICC (Immunocytochemistry) (Immunocytochemistry staining of HeLa cells fixed with 4% Paraformaldehyde and using anti-HP1-gamma antibody (dilution 1:200).)
Related Product Information for anti-HP1-gamma antibody
Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.
Product Categories/Family for anti-HP1-gamma antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
20,811 Da
NCBI Official Full Name
chromobox protein homolog 3
NCBI Official Synonym Full Names
chromobox homolog 3
NCBI Official Symbol
CBX3
NCBI Official Synonym Symbols
HECH; HP1-GAMMA; HP1Hs-gamma
NCBI Protein Information
chromobox protein homolog 3
UniProt Protein Name
Chromobox protein homolog 3
UniProt Gene Name
CBX3
UniProt Synonym Gene Names
HP1 gamma
UniProt Entry Name
CBX3_HUMAN

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Product Notes

The HP1-gamma cbx3 (Catalog #AAA300833) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The HP1-gamma Monoclonal Antibody reacts with Mouse, Human, Monkey, Hamster, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's HP1-gamma can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), IP (Immunoprecipitation), ICC (Immunocytochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the HP1-gamma cbx3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HP1-gamma, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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