Mouse HSP60 (Heat Shock Protein 60) Monoclonal Antibody | anti-HSPD1 antibody

HSP60 (Heat Shock Protein 60) (Mitochondrial Marker) Recombinant Mouse Monoclonal Antibody [Clone rHSPD1/6495]

Cat. Num. AAA215713

• Gene Names: HSPD1; HLD4; CPN60; GROEL; HSP60; HSP65; SPG13; HSP-60; HuCHA60
• Reactivity: Human, Monkey, Mouse, Rat, Hamster, Guinea pig and Chicken
• Applications: Immunohistochemistry, Western Blot
• Synonyms: HSP60 (Heat Shock Protein 60), Antibody; HSP60 (Heat Shock Protein 60) (Mitochondrial Marker) Recombinant Mouse Monoclonal Antibody [Clone rHSPD1/6495]; HSP60 (Heat Shock Protein 60) (Mitochondrial Marker); Chaperonin, 60-KD (CPN60), GROEL, HLD4, HSP65, HSPD1, HuCHA60, Mitochondrial matrix protein P1, P60 lymphocyte protein, Short heat shock protein 60 Hsp60s1, Spastic paraplegia 13 (SPG13); anti-HSPD1 antibody

• Host: Mouse
• Reactivity: Human, Monkey, Mouse, Rat, Hamster, Guinea pig and Chicken
• Clonality: Monoclonal
• Isotype: Mouse/IgG2a, kappa
• Clone Number: rHSPD1/6495
• Form/Format: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with0. 05% BSA & 0. 05% azide. Also available WITHOUT BSA at 1.0mg/ml.
• Concentration: Purified Ab with BSA and Azide at 200ug/ml; OR; Purified Ab WITHOUT BSA; OR; Azide at 1.0mg/ml (varies by lot)

• Applicable Applications for anti-HSPD1 antibody: IHC (Immunohistochemistry), WB (Western Blot)
• Antibody Type: Recombinant Antibody
• Immunogen: Recombinant full-length human HSPD1 protein
• Cellular Localization: Mitochondria in cytoplasm
• Positive Control: HeLa or HepG2 cells. Synovial biopsies from patients with juvenile chronic arthritis. Synovial lining layer is strongly positive for hsp60. Breast carcinoma.
• Hu-chromosome Location: 2q33.1
• Unigene: 595053
• Preparation and Storage: Antibody with azide: store at 2 to 8 degree C; Antibody is stable for 24 months. Non-hazardous. No MSDS required.

IHC (Immunohistochemistry)

(Formalin-fixed, paraffin-embedded human thyroid stained with HSP60Recombinant Mouse Monoclonal Antibody (rHSPD1/6495).)

Related Product Information for anti-HSPD1 antibody

Recognizes a 60kDa protein, identified as the heat shock protein 60 (hsp60). A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsp s), more appropriately called as stress response proteins (srp s). hsp60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial hsp60, but also against its mammalian homolog.

NCBI and Uniprot Product Information

• NCBI GI #: 31542947
• NCBI GeneID: 3329
• NCBI Accession #: NP_002147.2
• NCBI GenBank Nucleotide #: NM_002156.4
• UniProt Accession #: P10809; Q38L19; Q9UCR6; B2R5M6
• Molecular Weight: 61,055 Da
• NCBI Official Full Name: 60 kDa heat shock protein, mitochondrial
• NCBI Official Synonym Full Names: heat shock 60kDa protein 1 (chaperonin)
• NCBI Official Symbol: HSPD1
• NCBI Official Synonym Symbols: HLD4; CPN60; GROEL; HSP60; HSP65; SPG13; HSP-60; HuCHA60
• NCBI Protein Information: 60 kDa heat shock protein, mitochondrial; chaperonin 60; 60 kDa chaperonin; heat shock protein 65; P60 lymphocyte protein; mitochondrial matrix protein P1; short heat shock protein 60 Hsp60s1
• UniProt Protein Name: 60 kDa heat shock protein, mitochondrial
• UniProt Gene Name: HSPD1
• UniProt Synonym Gene Names: HSP60; CPN60; HSP-60; Hsp60
• UniProt Entry Name: CH60_HUMAN