Mouse anti-Mouse, Human Ikaros Monoclonal Antibody | anti-IKZF1 antibody
Anti-Ikaros Purified
Gene Names
IKZF1; IK1; LYF1; LyF-1; CVID13; IKAROS; PPP1R92; PRO0758; ZNFN1A1; Hs.54452
Reactivity
Mouse, Human
Applications
Immunocytochemistry, Western Blot, Immunoprecipitation, Flow Cytometry, Functional Assay
Purity
Purified by Protein-A Affinity Chromatography
Synonyms
Ikaros, Antibody; Anti-Ikaros Purified; IKAROS family zinc finger 1; IKZF1; IK1; LYF1; LyF-1; IKAROS; PPP1R92; PRO0758; ZNFN1A1; Hs.54452; Lymphoid transcription factor LyF-1; anti-IKZF1 antibody
Host
Mouse
Reactivity
Mouse, Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
4E9
Specificity
The mouse monoclonal antibody 4E9 recognizes Ikaros, a transcription factor (intracellular antigen) expressed broadly in hematopoietic progenitors and serving as a key regulator of lymphopoiesis.
Purity/Purification
Purified by Protein-A Affinity Chromatography
Form/Format
Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Concentration
1 mg/ml (varies by lot)
Sequence Length
519
Applicable Applications for anti-IKZF1 antibody
ICC (Immunocytochemistry), WB (Western Blot), IP (Immunoprecipitation), FCM/FACS (Flow Cytometry)
Immunogen
Recombinant human Ikaros (C-terminal part)
Preparation and Storage
Store at 2-8 degree C.
Related Product Information for anti-IKZF1 antibody
Ikaros, also known as IKZF1 (Ikaros family zinc finger protein 1) is a hematopoietic-specific transcription factor involved in the regulation of lymphocyte development, together with other members of this family, such as Aiolos and Helios. Ikaros forms homo- and heterodimers with these proteins and functions predominantly in early hematopoietic development. Expression of Ikaros, Aiolos and Helios is restricted to cells of the hematopoietic system, whereas other family members, Eos and Pegassus, are more widely expressed. Disruption of Ikaros leads to T and B cell leukemias.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
NCBI Official Full Name
DNA-binding protein Ikaros
NCBI Official Synonym Full Names
IKAROS family zinc finger 1
NCBI Official Symbol
IKZF1
NCBI Official Synonym Symbols
IK1; LYF1; LyF-1; CVID13; IKAROS; PPP1R92; PRO0758; ZNFN1A1; Hs.54452
NCBI Protein Information
DNA-binding protein Ikaros
UniProt Protein Name
DNA-binding protein Ikaros
UniProt Gene Name
IKZF1
UniProt Synonym Gene Names
IK1; IKAROS; LYF1; ZNFN1A1
UniProt Entry Name
IKZF1_HUMAN
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Product Notes
The IKZF1 ikzf1 (Catalog #AAA128351) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-Ikaros Purified reacts with Mouse, Human and may cross-react with other species as described in the data sheet. AAA Biotech's Ikaros can be used in a range of immunoassay formats including, but not limited to, ICC (Immunocytochemistry), WB (Western Blot), IP (Immunoprecipitation), FCM/FACS (Flow Cytometry). Researchers should empirically determine the suitability of the IKZF1 ikzf1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Ikaros, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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