IHC (Immunohistochemisry)
(Immunohistochemical analysis of paraffin-embedded human stomach cancer tissue using anti- Mre11 antibody. Counter stained with hematoxylin.)
Rabbit Mre11 Monoclonal Antibody | anti-Mre11 antibody
Mre11 Antibody
Gene Names
MRE11A; ATLD; HNGS1; MRE11; MRE11B
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot
Purity
ProA affinity purified
Synonyms
Mre11, Antibody; Mre11 Antibody; AT like disease antibody; Ataxia telangiectasia disorder like antibody; ATLD antibody; DNA recombination and repair protein antibody; Double strand break repair protein MRE11A antibody; Double-strand break repair protein MRE11A antibody; endo/exonuclease Mre11 antibody; HNGS1 antibody; meiotic recombination (S. cerevisiae) 11 homolog A antibody; Meiotic recombination 11 homolog 1 antibody; meiotic recombination 11 homolog A (S. cerevisiae) antibody; Meiotic recombination 11 homolog A antibody; MmMRE11A antibody; Mre 11 antibody; MRE 11a antibody; MRE 11b antibody; MRE11 homolog 1 antibody; MRE11 homolog A antibody; MRE11 meiotic recombination 11 homolog A (S. cerevisiae) antibody; MRE11 meiotic recombination 11 homolog A antibody; MRE11_HUMAN antibody; MRE11A antibody; MRE11b antibody; OTTHUMP00000236830 antibody; OTTHUMP00000236831 antibody; OTTHUMP00000236832 antibody; OTTHUMP00000236833 antibody; anti-Mre11 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Clone Number
JM11-18
Purity/Purification
ProA affinity purified
Form/Format
1*TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Applicable Applications for anti-Mre11 antibody
IHC (Immunohistochemistry), WB (Western Blot)
Antibody Type
Recombinant Antibody
Immunogen
Recombinant protein
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C.
IHC (Immunohistochemisry)
(Immunohistochemical analysis of paraffin-embedded human stomach cancer tissue using anti- Mre11 antibody. Counter stained with hematoxylin.)
IHC (Immunohistochemisry)
(Immunohistochemical analysis of paraffin-embedded human stomach cancer tissue using anti- Mre11 antibody. Counter stained with hematoxylin.)
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded human breast cancer tissue using anti- Mre11 antibody. Counter stained with hematoxylin.)
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded human breast cancer tissue using anti- Mre11 antibody. Counter stained with hematoxylin.)
WB (Western Blot)
(Western blot analysis of Mre11 on different cells lysates using anti-Mre11 antibody at 1/500 dilution. Positive control�� Line 1: 293T Line 2: Hela)
WB (Western Blot)
(Western blot analysis of Mre11 on different cells lysates using anti-Mre11 antibody at 1/500 dilution. Positive control�� Line 1: 293T Line 2: Hela)
Related Product Information for anti-Mre11 antibody
Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11. RAD50 may be required to bind DNA ends and hold them in close proximity. This could facilitate searches for short or long regions of sequence homology in the recombining DNA templates, and may also stimulate the activity of DNA ligases and/or restrict the nuclease activity of MRE11 to prevent nucleolytic degradation past a given point. The complex may also be required for DNA damage signaling via activation of the ATM kinase. In telomeres the MRN complex may modulate t-loop formation.
Product Categories/Family for anti-Mre11 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
80,593 Da
NCBI Official Full Name
double-strand break repair protein MRE11A isoform 2
NCBI Official Synonym Full Names
MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
NCBI Official Symbol
MRE11A
NCBI Official Synonym Symbols
ATLD; HNGS1; MRE11; MRE11B
NCBI Protein Information
double-strand break repair protein MRE11A; AT-like disease; MRE11 homolog 1; MRE11 homolog A; endo/exonuclease Mre11; meiotic recombination 11 homolog 1; meiotic recombination 11 homolog A; DNA recombination and repair protein
UniProt Protein Name
Double-strand break repair protein MRE11A
UniProt Gene Name
MRE11A
UniProt Synonym Gene Names
HNGS1; MRE11; MRE11 homolog 1
UniProt Entry Name
MRE11_HUMAN
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Product Notes
The Mre11 mre11a (Catalog #AAA312482) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Mre11 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Mre11 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the Mre11 mre11a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Mre11, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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