IHC (Immunohiostchemistry)
(Immunohistochemistry of MRE11 in rat lung tissue with MRE11 antibody at 5 ug/mL.)
Rabbit MRE11 Polyclonal Antibody | anti-MRE11 antibody
MRE11 Antibody
Gene Names
MRE11A; ATLD; HNGS1; MRE11; MRE11B
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Affinity chromatography purified via peptide column
Synonyms
MRE11, Antibody; MRE11 Antibody; Meiotic recombination 11 homolog, MRE11A, MRE11B, ATLD, HNGS; anti-MRE11 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
708
Applicable Applications for anti-MRE11 antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Immunogen Type
Peptide
Immunogen Description
Raised against a 14 amino acid peptide from near the amino terminus human MRE11.
Target Name
MRE11
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IHC (Immunohiostchemistry)
(Immunohistochemistry of MRE11 in rat lung tissue with MRE11 antibody at 5 ug/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of MRE11 in rat lung tissue with MRE11 antibody at 5 ug/mL.)
WB (Western Blot)
(Western blot analysis of MRE11 in rat lung tissue lysate with MRE11 antibody at (A) 1 and (B) 2 ug/mL.)
WB (Western Blot)
(Western blot analysis of MRE11 in rat lung tissue lysate with MRE11 antibody at (A) 1 and (B) 2 ug/mL.)
Related Product Information for anti-MRE11 antibody
MRE11 is involved in the repair of DNA double strand breaks as part of a complex that includes the Rad50 and NBS1 protein and is thought to act in the same pathway as the A-T mutated (ATM) protein. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for non-homologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. Mutations in this protein result in a novel ataxia telangiectasia-like disorder (ATLD). Unlike the ATM protein, MRE11 is necessary proper mammalian development.
Product Categories/Family for anti-MRE11 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
81,070 Da
NCBI Official Full Name
MRE11 meiotic recombination 11 homolog A (S. cerevisiae), isoform CRA_a
NCBI Official Synonym Full Names
MRE11 homolog A, double strand break repair nuclease
NCBI Official Symbol
MRE11A
NCBI Official Synonym Symbols
ATLD; HNGS1; MRE11; MRE11B
NCBI Protein Information
double-strand break repair protein MRE11A
UniProt Protein Name
Double-strand break repair protein MRE11A
UniProt Gene Name
MRE11A
UniProt Synonym Gene Names
HNGS1; MRE11; MRE11 homolog 1; MRE11 homolog A
UniProt Entry Name
MRE11_HUMAN
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Product Notes
The MRE11 mre11a (Catalog #AAA305472) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MRE11 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MRE11 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the MRE11 mre11a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MRE11, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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