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WB (Western Blot)
(Detection of human Mre11 by western blot. Samples: Whole cell lysate (50 ug) from HEK293T, HeLa, and Jurkat cells. Antibodies: Affinity purified rabbit anti-Mre11 antibody AAA212436 (lot AAA212436-1) used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.)
Rabbit anti-Human Mre11 Polyclonal Antibody | anti-MRE11 antibody
Rabbit anti-Mre11 Antibody, Affinity Purified
Gene Names
MRE11A; ATLD; HNGS1; MRE11; MRE11B
Reactivity
Human
Applications
Flow Cytometry, Functional Assay, Immunohistochemistry, Immunoprecipitation, Western Blot
Purity
Antigen Affinity Purified
Synonyms
Mre11, Antibody; Rabbit anti-Mre11 Antibody, Affinity Purified; MRE11B; MRE11 homolog 1; MRE11 homolog A; MRE11 homolog A, double strand break repair nuclease; MRE11 homolog, double strand break repair nuclease A; MRE11 meiotic recombination 11 homolog A; MRE11A; meiotic recombination 11 homolog 1; MRE11 meiotic recombination 11-like protein A; meiotic recombination 11 homolog A; HNGS1; endo/exonuclease Mre11; double-strand break repair protein MRE11A; double-strand break repair protein MRE11; DNA recombination and repair protein; AT-like disease; ATLD; MRE11 double strand break repair nuclease A; Double-strand break repair protein MRE11A; MRE11 homolog, double strand break repair nuclease; anti-MRE11 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid. Whole IgG. Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Concentration
1000ug/ml (varies by lot)
Applicable Applications for anti-MRE11 antibody
FCM/FACS (Flow Cytometry), IHC (Immunohistochemistry), IP (Immunoprecipitation), WB (Western Blot)
Immunogen
Between 658 and C-terminus
Conjugation
Unconjugated
Preparation and Storage
Store at 2-8 degree C
Shelf Life: 1 year from date of receipt
Shelf Life: 1 year from date of receipt
WB (Western Blot)
(Detection of human Mre11 by western blot. Samples: Whole cell lysate (50 ug) from HEK293T, HeLa, and Jurkat cells. Antibodies: Affinity purified rabbit anti-Mre11 antibody AAA212436 (lot AAA212436-1) used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.)
WB (Western Blot)
(Detection of human Mre11 by western blot. Samples: Whole cell lysate (50 ug) from HEK293T, HeLa, and Jurkat cells. Antibodies: Affinity purified rabbit anti-Mre11 antibody AAA212436 (lot AAA212436-1) used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.)
IP (Immunoprecipitation)
(Detection of human Mre11 by western blot of immunoprecipitates. Samples: Whole cell lysate (1 mg for IP; 20% of IP loaded) from HEK293T cells. Antibodies: Affinity purified rabbit anti-Mre11 antibody AAA212436 (lot AAA212436-1) used for IP at 6 ug/mg lysate. Mre11 was inefficiently immunoprecipitated by rabbit anti-Mre11 antibody BL14387. For blotting immunoprecipitated Mre11, AAA212436 was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.)
IP (Immunoprecipitation)
(Detection of human Mre11 by western blot of immunoprecipitates. Samples: Whole cell lysate (1 mg for IP; 20% of IP loaded) from HEK293T cells. Antibodies: Affinity purified rabbit anti-Mre11 antibody AAA212436 (lot AAA212436-1) used for IP at 6 ug/mg lysate. Mre11 was inefficiently immunoprecipitated by rabbit anti-Mre11 antibody BL14387. For blotting immunoprecipitated Mre11, AAA212436 was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.)
IHC (Immunohiostchemistry)
(Detection of human Mre11 by immunohistochemistry. Sample: FFPE section of human stomach linitis plastica. Antibody: Affinity purified rabbit anti-Mre11 (Cat. No. AAA212436 Lot1) used at a dilution of 1:1,000 (1ug/ml). Detection: DAB)
IHC (Immunohiostchemistry)
(Detection of human Mre11 by immunohistochemistry. Sample: FFPE section of human stomach linitis plastica. Antibody: Affinity purified rabbit anti-Mre11 (Cat. No. AAA212436 Lot1) used at a dilution of 1:1,000 (1ug/ml). Detection: DAB)
FCM/FACS (Flow Cytometry)
(Detection of human Mre11 (shaded) in Jurkat cells by flow cytometry. Antibody: Rabbit anti-Mre11 polyclonal antibody (AAA212436) or isotype control (unshaded). Secondary: DyLight 488-conjugated goat anti-rabbit IgG .)
FCM/FACS (Flow Cytometry)
(Detection of human Mre11 (shaded) in Jurkat cells by flow cytometry. Antibody: Rabbit anti-Mre11 polyclonal antibody (AAA212436) or isotype control (unshaded). Secondary: DyLight 488-conjugated goat anti-rabbit IgG .)
Related Product Information for anti-MRE11 antibody
Mre11 is a component of the MRN complex and plays a role in telomere maintenance and double-strand break (DSB) repair. Mre11 associates with rad50 in the MRN complex. Mre11 possesses 3'- 5' exonuclease activity that is involved in creating DNA termini in DSB suitable for priming DNA synthesis and ligation.
Product Categories/Family for anti-MRE11 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
81,070 Da
NCBI Official Full Name
double-strand break repair protein MRE11A isoform 1
NCBI Official Synonym Full Names
MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
NCBI Official Symbol
MRE11A
NCBI Official Synonym Symbols
ATLD; HNGS1; MRE11; MRE11B
NCBI Protein Information
double-strand break repair protein MRE11A; AT-like disease; MRE11 homolog 1; MRE11 homolog A; endo/exonuclease Mre11; meiotic recombination 11 homolog 1; meiotic recombination 11 homolog A; DNA recombination and repair protein
UniProt Protein Name
Double-strand break repair protein MRE11A
UniProt Gene Name
MRE11A
UniProt Synonym Gene Names
HNGS1; MRE11; MRE11 homolog 1
UniProt Entry Name
MRE11_HUMAN
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Product Notes
The MRE11 mre11a (Catalog #AAA212436) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-Mre11 Antibody, Affinity Purified reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Mre11 can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry), IHC (Immunohistochemistry), IP (Immunoprecipitation), WB (Western Blot). Researchers should empirically determine the suitability of the MRE11 mre11a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Mre11, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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