WB (Western Blot)
(Anti-Olig-2 rabbit monoclonal antibody at 1:500 dilutionLane A: Jurkat Whole Cell LysateLysates/proteins at 30 ug per lane.SecondaryGoat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution.Developed using the Odyssey technique.Performed under reducing conditions.Predicted band size:32 kDaObserved band size:37 kDa)
Rabbit anti-Human Olig2 Monoclonal Antibody | anti-OLIG2 antibody
Recombinant Anti-Olig2 Antibody, Rabbit Monoclonal
Gene Names
OLIG2; BHLHB1; OLIGO2; RACK17; PRKCBP2; bHLHe19
Reactivity
Human
Applications
Immunohistochemistry, Western Blot
Purity
Protein A
Synonyms
Olig2, Antibody; Recombinant Anti-Olig2 Antibody, Rabbit Monoclonal; Olig-2/Oligo2 Antibody, Rabbit MAb; oligodendrocyte transcription factor 2; Anti-BHLHB1 Antibody; Anti-bHLHe19 Antibody; Anti-OLIGO2 Antibody; Anti-PRKCBP2 Antibody; Anti-RACK17 Antibody; anti-OLIG2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Isotype
Rabbit IgG
Clone Number
064
Specificity
Human Olig-2/Oligo2
Purity/Purification
Protein A
Form/Format
Liquid; 0.2um filtered solution in PBS
Applicable Applications for anti-OLIG2 antibody
IHC (Immunohistochemistry), WB (Western Blot)
Antibody Type
Recombinant Antibody
Immunogen
A synthetic peptide corresponding to the N-terminus of the Human Olig-2
Conjugation
Unconjugated
Preparation
This antibody was obtained from a rabbit immunized with purified, synthetic peptide corresponding to the N-terminus of the Human Olig-2.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.
WB (Western Blot)
(Anti-Olig-2 rabbit monoclonal antibody at 1:500 dilutionLane A: Jurkat Whole Cell LysateLysates/proteins at 30 ug per lane.SecondaryGoat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution.Developed using the Odyssey technique.Performed under reducing conditions.Predicted band size:32 kDaObserved band size:37 kDa)
WB (Western Blot)
(Anti-Olig-2 rabbit monoclonal antibody at 1:500 dilutionLane A: Jurkat Whole Cell LysateLysates/proteins at 30 ug per lane.SecondaryGoat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution.Developed using the Odyssey technique.Performed under reducing conditions.Predicted band size:32 kDaObserved band size:37 kDa)
IHC (Immunohiostchemistry)
(Immunochemical staining of human olig-2 in human brain with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).)
IHC (Immunohiostchemistry)
(Immunochemical staining of human olig-2 in human brain with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).)
IHC (Immunohistochemistry)
(Immunochemical staining of human olig-2 in human glioma with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).)
IHC (Immunohistochemistry)
(Immunochemical staining of human olig-2 in human glioma with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).)
Related Product Information for anti-OLIG2 antibody
Olig2, also known as Oligo2, is a basic helix-loop-helix transcription factor that is expressed in oligodendroglial tumors of the brain. Oligo2 is structurally similar to OLIG1. Both of them have non-overlapping developmental functions in patterning, neuron subtype specification, and the formation of oligodendrocytes. Olig2 is required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. Its over-expression inhibits neural progenitor proliferation through changes in potassium channel activity, thereby contributing to the reduced neuronal numbers and brain size in down syndrome. Olig2 may be a cause of a form of T-cell acute lymphoblastic leukemia.
References
Wang J, et al., 2000, Proc Natl Acad Sci. 97(7): 3497-502.Lu QR, et al., 2001, Proc Natl Acad Sci. 98(19): 10851-6. Marie Y, et al., 2001, Lancet. 358(9278): 298-300.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Predicted: 36 kDa
Observed: 37 kDa
Observed: 37 kDa
NCBI Official Full Name
oligodendrocyte transcription factor 2
NCBI Official Synonym Full Names
oligodendrocyte lineage transcription factor 2
NCBI Official Symbol
OLIG2
NCBI Official Synonym Symbols
BHLHB1; OLIGO2; RACK17; PRKCBP2; bHLHe19
NCBI Protein Information
oligodendrocyte transcription factor 2; protein kinase C-binding protein 2; class B basic helix-loop-helix protein 1; class E basic helix-loop-helix protein 19; human protein kinase C-binding protein RACK17; basic domain, helix-loop-helix protein, class B
UniProt Protein Name
Oligodendrocyte transcription factor 2
UniProt Gene Name
OLIG2
UniProt Synonym Gene Names
BHLHB1; BHLHE19; PRKCBP2; RACK17; Oligo2; bHLHb1; bHLHe19
UniProt Entry Name
OLIG2_HUMAN
Similar Products
Product Notes
The OLIG2 olig2 (Catalog #AAA254146) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Recombinant Anti-Olig2 Antibody, Rabbit Monoclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Olig2 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the OLIG2 olig2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Olig2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.