Mouse Thymidylate Synthase Monoclonal Antibody | anti-TYMS antibody
Anti-Thymidylate Synthase Monoclonal Antibody
Gene Names
TYMS; TS; TMS; HST422; MGC88736
Applications
Immunoprecipitation, Immunohistochemistry, Immunoblot, Western Blot, ELISA
Synonyms
Thymidylate Synthase, Antibody; Anti-Thymidylate Synthase Monoclonal Antibody; Anti-Thymidylate Synthase; Thymidylate Synthase; anti-TYMS antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1
Specificity
Anti-Thymidylate Synthase [Murine MAb to human thymidylate synthase, a drug resistance-associated enzyme.]
These antibodies specifically recognize human TS (36 kDa). They do not crossreact with rat TS.
These antibodies specifically recognize human TS (36 kDa). They do not crossreact with rat TS.
Form/Format
200 ug Protein G-purified antibody in PBS, pH 7.4.
Sequence Length
313
Applicable Applications for anti-TYMS antibody
IP (Immunoprecipitation), IHC (Immunohistochemistry), IB (Immunoblot), ELISA
Antigen
Recombinant human thymidylate synthase produced in E. coli.
Stabilizer
None
Preservatives
None. Available on request.
Dilutions Instructions
Dilute in PBS or medium which is identical to that used in the assay system.
Preparation and Storage
This antibody is stable for at least one (1) year at -20 degree C. Avoid multiple freeze-thaw cycles.
Related Product Information for anti-TYMS antibody
Thymidylate synthase (TS) is an intracellular enzyme critical for de novo synthesis of DNA. In cancer, expression of TS is often elevated and becomes further elevated as a result of treatment with the most commonly used chemotherapeutic, 5-fluorouracil (5-FU). Resistance or lack of response to 5-FU is attributed to the elevation of TS activity. Overexpression of TS has been demonstrated in many types of tumors including breast, colon, gastric and melanoma and is usually predictive of shortened survival time.
Product Categories/Family for anti-TYMS antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
35,716 Da
NCBI Official Full Name
thymidylate synthase
NCBI Official Synonym Full Names
thymidylate synthetase
NCBI Official Symbol
TYMS
NCBI Official Synonym Symbols
TS; TMS; HST422; MGC88736
NCBI Protein Information
thymidylate synthase; TSase; OTTHUMP00000162195
UniProt Protein Name
Thymidylate synthase
UniProt Gene Name
TYMS
UniProt Synonym Gene Names
TS
UniProt Entry Name
TYSY_HUMAN
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Product Notes
The TYMS tyms (Catalog #AAA47650) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Thymidylate Synthase can be used in a range of immunoassay formats including, but not limited to, IP (Immunoprecipitation), IHC (Immunohistochemistry), IB (Immunoblot), ELISA. Researchers should empirically determine the suitability of the TYMS tyms for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Thymidylate Synthase, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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