WB (Western Blot)
(TRAF2/MB10188 antibody western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the TRAF2/MB10188 antibody detected the TRAF2/MB10188 protein (arrow).)
Mouse anti-Human TRAF2 Monoclonal Antibody | anti-TRAF2 antibody
TRAF2 Antibody
Gene Names
TRAF2; TRAP; TRAP3; MGC:45012
Reactivity
Human
Applications
Western Blot, ELISA, Immunofluorescence
Synonyms
TRAF2, Antibody; TRAF2 Antibody; TNF receptor-associated factor 2; 632-; E3 ubiquitin-protein ligase TRAF2; Tumor necrosis factor type 2 receptor-associated protein 3; TRAF2; TRAP3; anti-TRAF2 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1,K
Clone Number
214CT16.3.4
Specificity
This TRAF2 monoclonal antibody is generated from mouse immunized with TRAF2 recombinant protein.
Form/Format
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Length
501
Applicable Applications for anti-TRAF2 antibody
WB (Western Blot), ELISA, IF (Immunofluorescence)
Antigen Type
Recombinant Protein
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
WB (Western Blot)
(TRAF2/MB10188 antibody western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the TRAF2/MB10188 antibody detected the TRAF2/MB10188 protein (arrow).)
WB (Western Blot)
(TRAF2/MB10188 antibody western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the TRAF2/MB10188 antibody detected the TRAF2/MB10188 protein (arrow).)
IF (Immunofluorescence)
(Confocal immunofluorescent analysis of TRAF2 Antibody with MCF-7 cell followed by Alexa Fluor 488-conjugated goat anti-mouse lgG (green). DAPI was used to stain the cell nuclear (blue).)
IF (Immunofluorescence)
(Confocal immunofluorescent analysis of TRAF2 Antibody with MCF-7 cell followed by Alexa Fluor 488-conjugated goat anti-mouse lgG (green). DAPI was used to stain the cell nuclear (blue).)
Related Product Information for anti-TRAF2 antibody
The protein encoded by this gene is a member of the TNF
receptor associated factor (TRAF) protein family. TRAF proteins
associate with, and mediate the signal transduction from members of
the TNF receptor superfamily. This protein directly interacts with
TNF receptors, and forms a heterodimeric complex with TRAF1. This
protein is required for TNF-alpha-mediated activation of MAPK8/JNK
and NF-kappaB. The protein complex formed by this protein and TRAF1
interacts with the inhibitor-of-apoptosis proteins (IAPs), and
functions as a mediator of the anti-apoptotic signals from TNF
receptors. The interaction of this protein with TRADD, a TNF
receptor associated apoptotic signal transducer, ensures the
recruitment of IAPs for the direct inhibition of caspase
activation. BIRC2/c-IAP1, an apoptosis inhibitor possessing
ubiquitin ligase activity, can unbiquitinate and induce the
degradation of this protein, and thus potentiate TNF-induced
apoptosis. Multiple alternatively spliced transcript variants have
been found for this gene, but the biological validity of only one
transcript has been determined.
receptor associated factor (TRAF) protein family. TRAF proteins
associate with, and mediate the signal transduction from members of
the TNF receptor superfamily. This protein directly interacts with
TNF receptors, and forms a heterodimeric complex with TRAF1. This
protein is required for TNF-alpha-mediated activation of MAPK8/JNK
and NF-kappaB. The protein complex formed by this protein and TRAF1
interacts with the inhibitor-of-apoptosis proteins (IAPs), and
functions as a mediator of the anti-apoptotic signals from TNF
receptors. The interaction of this protein with TRADD, a TNF
receptor associated apoptotic signal transducer, ensures the
recruitment of IAPs for the direct inhibition of caspase
activation. BIRC2/c-IAP1, an apoptosis inhibitor possessing
ubiquitin ligase activity, can unbiquitinate and induce the
degradation of this protein, and thus potentiate TNF-induced
apoptosis. Multiple alternatively spliced transcript variants have
been found for this gene, but the biological validity of only one
transcript has been determined.
Product Categories/Family for anti-TRAF2 antibody
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Song, Y.J., et al. Virus Genes 41(2):174-180(2010)
Mace, P.D., et al. J. Mol. Biol. 400(1):8-15(2010)
Alvarez, S.E., et al. Nature 465(7301):1084-1088(2010)
Zhang, W., et al. Chin. Med. Sci. J. 25(1):1-12(2010)
Song, Y.J., et al. Virus Genes 41(2):174-180(2010)
Mace, P.D., et al. J. Mol. Biol. 400(1):8-15(2010)
Alvarez, S.E., et al. Nature 465(7301):1084-1088(2010)
Zhang, W., et al. Chin. Med. Sci. J. 25(1):1-12(2010)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
55859
NCBI Official Full Name
TNF receptor-associated factor 2
NCBI Official Synonym Full Names
TNF receptor-associated factor 2
NCBI Official Symbol
TRAF2
NCBI Official Synonym Symbols
TRAP; TRAP3; MGC:45012
NCBI Protein Information
TNF receptor-associated factor 2
UniProt Protein Name
TNF receptor-associated factor 2
UniProt Gene Name
TRAF2
UniProt Synonym Gene Names
TRAP3
UniProt Entry Name
TRAF2_HUMAN
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Product Notes
The TRAF2 traf2 (Catalog #AAA283582) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The TRAF2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TRAF2 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), ELISA, IF (Immunofluorescence). Researchers should empirically determine the suitability of the TRAF2 traf2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TRAF2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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