IF (Immunofluorescence)
(Glypican genes dally and dlp were required for JAK/STAT signaling activity and Upd distribution. A-B: dally was expressed in the eye discs in both 2nd instar larval stage (A-A") and early 3rd instar larval stage (B-B"). Expression of dally was marked by dally-lacZ (red in A' and B'), and overlapped with pSTAT staining (green in A-B).(References: Yan Zhang. ect. Drosophila glypicans Dally and Dally-like are essential regulators for JAK/STAT signaling and Unpaired distribution in eye development. Dev Biol. 2013 Mar 1;375(1):23-32. doi: 10.1016/j.ydbio.2012.12.019. Epub 2013 Jan 8.))
Mouse Phospho-STAT92E (Y711) Antibody | anti-STAT92E antibody
Phospho-STAT92E (Y711) Antibody
Reactivity
Drosophila melanogaster (Fruit fly)
Applications
Immunofluorescence, Western Blot
Synonyms
Phospho-STAT92E (Y711); N/A; Phospho-STAT92E (Y711) Antibody; Signal transducer and transcription activator; d-STAT; Protein marelle; Stat92E; MARE; mrL; Stat; CG4257; anti-STAT92E antibody
Host
Mouse
Reactivity
Drosophila melanogaster (Fruit fly)
Specificity
Phospho-STAT92E (Y711) antibody detects endogenous levels of STAT92E only when phosphorylated at Tyrosine 711.
Applicable Applications for anti-STAT92E antibody
IF (Immunofluorescence), WB (Western Blot)
Preparation and Storage
Store at -20 degree C. Stable for approximately 12 months from date of receipt.
IF (Immunofluorescence)
(Glypican genes dally and dlp were required for JAK/STAT signaling activity and Upd distribution. A-B: dally was expressed in the eye discs in both 2nd instar larval stage (A-A") and early 3rd instar larval stage (B-B"). Expression of dally was marked by dally-lacZ (red in A' and B'), and overlapped with pSTAT staining (green in A-B).(References: Yan Zhang. ect. Drosophila glypicans Dally and Dally-like are essential regulators for JAK/STAT signaling and Unpaired distribution in eye development. Dev Biol. 2013 Mar 1;375(1):23-32. doi: 10.1016/j.ydbio.2012.12.019. Epub 2013 Jan 8.))
IF (Immunofluorescence)
(Glypican genes dally and dlp were required for JAK/STAT signaling activity and Upd distribution. A-B: dally was expressed in the eye discs in both 2nd instar larval stage (A-A") and early 3rd instar larval stage (B-B"). Expression of dally was marked by dally-lacZ (red in A' and B'), and overlapped with pSTAT staining (green in A-B).(References: Yan Zhang. ect. Drosophila glypicans Dally and Dally-like are essential regulators for JAK/STAT signaling and Unpaired distribution in eye development. Dev Biol. 2013 Mar 1;375(1):23-32. doi: 10.1016/j.ydbio.2012.12.019. Epub 2013 Jan 8.))
WB (Western Blot)
(The levels of pStat92E and Stat92E are diminished in p115-depleted GSCs. (D) Western blot analysis and quantification of the levels of pStat92E protein in adult testes with indicated genotypes. b-Tubulin was used as blotting control. Data are shown as mean ± SD (n = 3). Two-tailed Student's t test was used. *p < 0.05.(References: Ruiyan Kong. ect. A feedforward loop between JAK/STAT downstream target p115 and STAT in germline stem cells. Stem Cell Reports. 2023 Oct 10;18(10):1940-1953. doi: 10.1016/j.stemcr.2023.08.007. Epub 2023 Sep 7.))
WB (Western Blot)
(The levels of pStat92E and Stat92E are diminished in p115-depleted GSCs. (D) Western blot analysis and quantification of the levels of pStat92E protein in adult testes with indicated genotypes. b-Tubulin was used as blotting control. Data are shown as mean ± SD (n = 3). Two-tailed Student's t test was used. *p < 0.05.(References: Ruiyan Kong. ect. A feedforward loop between JAK/STAT downstream target p115 and STAT in germline stem cells. Stem Cell Reports. 2023 Oct 10;18(10):1940-1953. doi: 10.1016/j.stemcr.2023.08.007. Epub 2023 Sep 7.))
Related Product Information for anti-STAT92E antibody
In Drosophila, hopscotch (hop) and STAT92E/marelle encode for Drosophila JAK and STAT, respectively, while domeless (dome) encodes for the only receptor. Might play a role in signal transduction and activation of transcription. Plays an important role in the segmental pattern formation in the early embryo by activating specific stripes of pair rule gene expression in early development as part of the Janus kinase-STAT pathway (PubMed:8608595).Might play a role in male germline stem cell maintenance (PubMed:34644293).
NCBI and Uniprot Product Information
UniProt Accession #
Molecular Weight
86kDa
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Product Notes
The STAT92E (Catalog #AAA62492) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Phospho-STAT92E (Y711) Antibody reacts with Drosophila melanogaster (Fruit fly) and may cross-react with other species as described in the data sheet. AAA Biotech's Phospho-STAT92E (Y711) can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), WB (Western Blot). Researchers should empirically determine the suitability of the STAT92E for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Phospho-STAT92E (Y711), Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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