FCM/FACS (Flow Cytometry)
(Figure 3: Flow cytometric analysis of PC-3 cells using CD276 mouse mAb (green) and negative control (purple).)
Mouse anti-Human CD276 Antibody | anti-CD276 antibody
CD276 Antibody
Gene Names
CD276; B7H3; B7-H3; B7RP-2; 4Ig-B7-H3
Reactivity
Human
Applications
ELISA, Flow Cytometry, Functional Assay, Immunofluorescence, Western Blot
Synonyms
CD276; N/A; CD276 Antibody; B7H3; B7-H3; 4Ig-B7-H3; anti-CD276 antibody
Host
Mouse
Reactivity
Human
Isotype
IgG1
Clone Number
6A1
Form/Format
Ascitic fluid containing 0.03% sodium azide.
Sequence Length
534
Applicable Applications for anti-CD276 antibody
ELISA, FCM/FACS (Flow Cytometry), IF (Immunofluorescence), WB (Western Blot)
Immunogen
Purified recombinant fragment of human CD276 expressed in E. Coli.
Preparation and Storage
Store at 4 degree C, for long term storage, store at-20 degree C.
FCM/FACS (Flow Cytometry)
(Figure 3: Flow cytometric analysis of PC-3 cells using CD276 mouse mAb (green) and negative control (purple).)
FCM/FACS (Flow Cytometry)
(Figure 3: Flow cytometric analysis of PC-3 cells using CD276 mouse mAb (green) and negative control (purple).)
IHC (Immunohiostchemistry)
(Figure 2: Immunohistochemical analysis of paraffin-embedded cervical cancer tissues (left) and ovarian cancer tissues (right) using CD276 mouse mAb with DAB staining.)
IHC (Immunohiostchemistry)
(Figure 2: Immunohistochemical analysis of paraffin-embedded cervical cancer tissues (left) and ovarian cancer tissues (right) using CD276 mouse mAb with DAB staining.)
WB (Western Blot)
(Figure 1: Western blot analysis using CD276 mAb against HEK293 (1) and CD276-hIgGFc transfected HEK293 (2) cell lysate.)
WB (Western Blot)
(Figure 1: Western blot analysis using CD276 mAb against HEK293 (1) and CD276-hIgGFc transfected HEK293 (2) cell lysate.)
Related Product Information for anti-CD276 antibody
Costimulatory B7 molecules (e.g., B7-1, or CD80; MIM 112203) signal through CD28 (MIM 186760) family molecules such as CD28, CTLA4 (MIM 123890), and ICOS (MIM 604558). May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. Isoform 2 is shown to enhance the induction of cytotoxic T-cells and selectively stimulates interferon gamma production in the presence of T-cell receptor signaling.
Product Categories/Family for anti-CD276 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
57kDa
NCBI Official Full Name
CD276 antigen isoform a
NCBI Official Synonym Full Names
CD276 molecule
NCBI Official Symbol
CD276
NCBI Official Synonym Symbols
B7H3; B7-H3; B7RP-2; 4Ig-B7-H3
NCBI Protein Information
CD276 antigen
UniProt Protein Name
CD276 antigen
UniProt Gene Name
CD276
UniProt Synonym Gene Names
B7H3; B7-H3
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Product Notes
The CD276 cd276 (Catalog #AAA108610) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CD276 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CD276 can be used in a range of immunoassay formats including, but not limited to, ELISA, FCM/FACS (Flow Cytometry), IF (Immunofluorescence), WB (Western Blot). Researchers should empirically determine the suitability of the CD276 cd276 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD276, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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