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product-image-AAA210986_WB13.jpg WB (Western Blot) (Detection of 4EBP1 by western blot. Samples: Whole cell lysate (100 ug) from RINm5F insulinoma exposed to high or low concentration of leucine. Antibody: Affinity purified rabbit anti-4EBP1 (Cat. No. AAA210986) used at 0.25 ug/ml. Detection: Chemiluminescence.)

Rabbit anti-Human 4EBP1 Polyclonal Antibody | anti-4EBP1 antibody

Rabbit anti-4EBP1 Antibody, Affinity Purified

Gene Names
EIF4EBP1; BP-1; 4EBP1; 4E-BP1; PHAS-I
Reactivity
Human
Applications
Immunohistochemistry, Western Blot
Purity
Antigen Affinity Purified
Synonyms
4EBP1, Antibody; Rabbit anti-4EBP1 Antibody, Affinity Purified; 4EBP1; 4E-BP1; BP-1; eIF4E-binding protein 1; eukaryotic translation initiation factor 4E-binding protein 1; PHAS-I; phosphorylated heat- and acid-stable protein regulated by insulin 1; Eukaryotic translation initiation factor 4E-binding protein 1; eukaryotic translation initiation factor 4E binding protein 1; anti-4EBP1 antibody
Ordering
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid. Whole IgG. Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Concentration
1000ug/ml (varies by lot)
Applicable Applications for anti-4EBP1 antibody
IHC (Immunohistochemistry), WB (Western Blot)
Predicted Reactivity
Mouse, Rat
Immunogen
Between 68 and C-terminus
Conjugation
Unconjugated
Preparation and Storage
Store at 2-8 degree C
Shelf Life: 1 year from date of receipt

WB (Western Blot)

(Detection of 4EBP1 by western blot. Samples: Whole cell lysate (100 ug) from RINm5F insulinoma exposed to high or low concentration of leucine. Antibody: Affinity purified rabbit anti-4EBP1 (Cat. No. AAA210986) used at 0.25 ug/ml. Detection: Chemiluminescence.)

product-image-AAA210986_WB13.jpg WB (Western Blot) (Detection of 4EBP1 by western blot. Samples: Whole cell lysate (100 ug) from RINm5F insulinoma exposed to high or low concentration of leucine. Antibody: Affinity purified rabbit anti-4EBP1 (Cat. No. AAA210986) used at 0.25 ug/ml. Detection: Chemiluminescence.)

IHC (Immunohistochemistry)

(Detection of human 4EBP1 by immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-4EBP1 (Cat. No. AAA210986) used at a dilution of 1:20,000 (0.05ug/ml). Detection: DAB)

product-image-AAA210986_IHC15.jpg IHC (Immunohistochemistry) (Detection of human 4EBP1 by immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-4EBP1 (Cat. No. AAA210986) used at a dilution of 1:20,000 (0.05ug/ml). Detection: DAB)
Related Product Information for anti-4EBP1 antibody
Eukaryotic translation initiation factor 4E-binding protein 1 (4EBP1) binds directly to eIF4E to inhibit complex assembly for translation initiation. 4EBP1 is part of a family of translation repressor proteins. 4EBP1 is directly phosphorylated by the mTORC1 complex during growth factor stimulation of cells. Phosphorylation of 4EBP1 causes its release from eIF4E to allow translation to proceed.
Product Categories/Family for anti-4EBP1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
12,580 Da
NCBI Official Full Name
eukaryotic translation initiation factor 4E-binding protein 1
NCBI Official Synonym Full Names
eukaryotic translation initiation factor 4E binding protein 1
NCBI Official Symbol
EIF4EBP1
NCBI Official Synonym Symbols
BP-1; 4EBP1; 4E-BP1; PHAS-I
NCBI Protein Information
eukaryotic translation initiation factor 4E-binding protein 1; eIF4E-binding protein 1; phosphorylated heat- and acid-stable protein regulated by insulin 1
UniProt Protein Name
Eukaryotic translation initiation factor 4E-binding protein 1
UniProt Gene Name
EIF4EBP1
UniProt Synonym Gene Names
4E-BP1; eIF4E-binding protein 1; PHAS-I
UniProt Entry Name
4EBP1_HUMAN

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Product Notes

The 4EBP1 eif4ebp1 (Catalog #AAA210986) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-4EBP1 Antibody, Affinity Purified reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's 4EBP1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the 4EBP1 eif4ebp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "4EBP1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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