ICC (Immunocytochemistry)
(Immunocytochemistry of Bak in L1210 cells with Bak antibody at 2 μg/mL.)
Rabbit anti-Human, Mouse Bak Polyclonal Antibody | anti-BAK1 antibody
Bak Antibody
Gene Names
BAK1; BAK; CDN1; BCL2L7; BAK-LIKE
Reactivity
Human, Mouse
Applications
Immunocytochemistry, Western Blot, ELISA
Purity
Bak Antibody is affinity chromatography purified via peptide column.
Synonyms
Bak, Antibody; Bak Antibody; Bak; BAK; CDN1; BCL2L7; BAK-LIKE; Apoptosis regulator BAK; Bcl2-L-7; BCL2-antagonist/killer 1; anti-BAK1 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Bak Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
211
Applicable Applications for anti-BAK1 antibody
ICC (Immunocytochemistry), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
Bak antibody was raised against a peptide corresponding to 13 amino acids near the amino-terminus of human Bak.
Buffer
Bak Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
Bak antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
ICC (Immunocytochemistry)
(Immunocytochemistry of Bak in L1210 cells with Bak antibody at 2 μg/mL.)
ICC (Immunocytochemistry)
(Immunocytochemistry of Bak in L1210 cells with Bak antibody at 2 μg/mL.)
WB (Western Blot)
(Western blot analysis of Bak in L1210 cell lysates with Bak antibody at (A) 1 and (B) 2 μg/mL.)
WB (Western Blot)
(Western blot analysis of Bak in L1210 cell lysates with Bak antibody at (A) 1 and (B) 2 μg/mL.)
Related Product Information for anti-BAK1 antibody
Bak Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death. Bak, a pro-apoptotic Bcl-2 family member, is an oligomeric protein that localizes to the mitochondria. It is thought to share significant functional homology with Bax, another pro-apoptotic Bcl-2 family member, as disruption of bak or bax has little effect on cell death, but mice lacking both genes display multiple developmental defects and cells lacking bak and bax show decreased apoptotic capability.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
16,872 Da
NCBI Official Full Name
Bcl-2 homologous antagonist/killer
NCBI Official Synonym Full Names
BCL2-antagonist/killer 1
NCBI Official Symbol
BAK1
NCBI Official Synonym Symbols
BAK; CDN1; BCL2L7; BAK-LIKE
NCBI Protein Information
bcl-2 homologous antagonist/killer; bcl2-L-7; BCL2-like 7 protein; bcl-2-like protein 7; apoptosis regulator BAK; pro-apoptotic protein BAK
UniProt Protein Name
Bcl-2 homologous antagonist/killer
UniProt Gene Name
BAK1
UniProt Synonym Gene Names
BAK; BCL2L7; CDN1; Bcl2-L-7
UniProt Entry Name
BAK_HUMAN
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Product Notes
The BAK1 bak1 (Catalog #AAA40291) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Bak Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Bak can be used in a range of immunoassay formats including, but not limited to, ICC (Immunocytochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the BAK1 bak1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Bak, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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