WB (Western Blot)
(WB Suggested Anti-CCL2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Transfected 293T)
Rabbit CCL2 Polyclonal Antibody | anti-CCL2 antibody
CCL2 antibody - middle region
Gene Names
CCL2; HC11; MCAF; MCP1; MCP-1; SCYA2; GDCF-2; SMC-CF; HSMCR30
Reactivity
Tested Species Reactivity: HumanPredicted Species Reactivity: Human, Dog
Applications
Western Blot, Immunohistochemistry
Purity
Affinity Purified
Synonyms
CCL2, Antibody; CCL2 antibody - middle region; anti-CCL2 antibody
Host
Rabbit
Reactivity
Tested Species Reactivity: Human
Predicted Species Reactivity: Human, Dog
Predicted Species Reactivity: Human, Dog
Clonality
Polyclonal
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration
0.5 mg/ml (varies by lot)
Sequence
Synthetic peptide located within the following region: ASYRRITSSKCPKEAVIFKTIVAKEICADPKQKWVQDSMDHLDKQTQTPK
Sequence Length
99
Applicable Applications for anti-CCL2 antibody
WB (Western Blot), IHC (Immunohistochemistry)
Predicted Homology
Dog: 75%; Human: 100%
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human CCL2
Protein Size (# AA)
99 amino acids
Protein Interactions
Ccr2; CDC45; PCNA; ORC4; ORC2; MCM7; MCM3; MCM2; CDC6; ACKR2; ACKR4; CCR5; CCR1; CCR10; MMP3; CCL2; MMP8; MMP1; VCAN; ACKR1; CCL5; CCR3;
Blocking Peptide
For anti-CCL2 (MBS3224420) antibody is Catalog #
Preparation and Storage
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
WB (Western Blot)
(WB Suggested Anti-CCL2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Transfected 293T)
WB (Western Blot)
(WB Suggested Anti-CCL2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Transfected 293T)
IHC (Immunohiostchemistry)
(Sample Type: human macrophagesSample Type:Human Macrophange CellsGreen:primaryRed:phallodinBlue:DAPIYellow:green/redPrimary Dilution:1:200Secondary Antibody:anti-Rabbit IgG-FITCSecondary Dilution:1:1000Image Submitted By:Milan FialaUniversity of California, Los Angeles)
IHC (Immunohiostchemistry)
(Sample Type: human macrophagesSample Type:Human Macrophange CellsGreen:primaryRed:phallodinBlue:DAPIYellow:green/redPrimary Dilution:1:200Secondary Antibody:anti-Rabbit IgG-FITCSecondary Dilution:1:1000Image Submitted By:Milan FialaUniversity of California, Los Angeles)
IHC (Immunohistochemistry)
(Sample Type: Human KidneySample Type: Kidney)
IHC (Immunohistochemistry)
(Sample Type: Human KidneySample Type: Kidney)
Related Product Information for anti-CCL2 antibody
This is a rabbit polyclonal antibody against CCL2. It was validated on Western Blot using a cell lysate as a positive control.
Target Description: CCL2 is a chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. CCL2 augments monocyte anti-tumor activity. CCL2 has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. CCL2 may be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis.This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Target Description: CCL2 is a chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. CCL2 augments monocyte anti-tumor activity. CCL2 has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. CCL2 may be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis.This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Product Categories/Family for anti-CCL2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
11kDa
NCBI Official Full Name
C-C motif chemokine 2
NCBI Official Synonym Full Names
C-C motif chemokine ligand 2
NCBI Official Symbol
CCL2
NCBI Official Synonym Symbols
HC11; MCAF; MCP1; MCP-1; SCYA2; GDCF-2; SMC-CF; HSMCR30
NCBI Protein Information
C-C motif chemokine 2
UniProt Protein Name
C-C motif chemokine 2
UniProt Gene Name
CCL2
UniProt Synonym Gene Names
MCP1; SCYA2; MCAF; MCP-1
UniProt Entry Name
CCL2_HUMAN
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Product Notes
The CCL2 ccl2 (Catalog #AAA201692) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CCL2 antibody - middle region reacts with Tested Species Reactivity: Human Predicted Species Reactivity: Human, Dog and may cross-react with other species as described in the data sheet. AAA Biotech's CCL2 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the CCL2 ccl2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: ASYRRITSSK CPKEAVIFKT IVAKEICADP KQKWVQDSMD HLDKQTQTPK. It is sometimes possible for the material contained within the vial of "CCL2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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