IHC (Immunohiostchemistry)
(CD2 Antibody-Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE))
Rabbit anti-Human CD2 Polyclonal Antibody | anti-CD2 antibody
CD2 Rabbit anti-Human Polyclonal Antibody
Gene Names
CD2; T11; SRBC; LFA-2
Reactivity
Human
Applications
Immunohistochemistry
Purity
Immunoaffinity purified
Synonyms
CD2, Antibody; CD2 Rabbit anti-Human Polyclonal Antibody; PathPlus CD2 Antibody; CD2; CD2 antigen; Erythrocyte receptor; LFA-3 receptor; LFA-2; Lymphocyte-function antigen-2; T11; SRBC; CD2 molecule; Rosette receptor; T-cell surface antigen CD2; anti-CD2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Immunoaffinity purified
Form/Format
PBS, 0.1% Sodium Azide
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-CD2 antibody
IHC (Immunohistochemistry)
Target
Human CD2
Immunogen
LP-10927, synthetic peptide
Conjugation
Unconjugated
Preparation and Storage
Aliquot and store undiluted at -20 degree C or below for up to 1 year. Can be stored undiluted at 4 degree C for up to 1 month. Avoid freeze-thaw cycles.
IHC (Immunohiostchemistry)
(CD2 Antibody-Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohiostchemistry)
(CD2 Antibody-Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohistochemistry)
(CD2 Antibody-Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohistochemistry)
(CD2 Antibody-Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE))
Related Product Information for anti-CD2 antibody
CD2 antibody is an unconjugated rabbit polyclonal antibody to CD2 from human. Validated for IHC.
CD2 is a cell adhesion molecule that is found on the plasma membrane of peripheral T-lymphocytes, thymocytes, natural killer cells, Langerhans cells, and mast cells. It mediates adhesion between T-cells and antigen processing cells, induces co-stimulatory signals in T-cells and T-cell cytokine production, regulates T and NK mediated cytolysis, and inhibits apoptosis of activated peripheral T-cells. CD2 also distinguishes between two subsets of human plasmacytoid dendritic cells with distinct phenotypes and functions. In malignancies, CD2 is expressed on T-cell lymphomas, anaplastic large cell lymphomas, and T-cell leukemias, which helps to differentiate them from negatively staining B-cell neoplasms. The marker is also positive in some mast cell proliferative diseases.
CD2 is a cell adhesion molecule that is found on the plasma membrane of peripheral T-lymphocytes, thymocytes, natural killer cells, Langerhans cells, and mast cells. It mediates adhesion between T-cells and antigen processing cells, induces co-stimulatory signals in T-cells and T-cell cytokine production, regulates T and NK mediated cytolysis, and inhibits apoptosis of activated peripheral T-cells. CD2 also distinguishes between two subsets of human plasmacytoid dendritic cells with distinct phenotypes and functions. In malignancies, CD2 is expressed on T-cell lymphomas, anaplastic large cell lymphomas, and T-cell leukemias, which helps to differentiate them from negatively staining B-cell neoplasms. The marker is also positive in some mast cell proliferative diseases.
References
J Exp Med 1999;190:1383; Immunology 2013;139:48; J Immunol 2009;182:6815
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
39,448 Da
NCBI Official Full Name
T-cell surface antigen CD2
NCBI Official Synonym Full Names
CD2 molecule
NCBI Official Symbol
CD2
NCBI Official Synonym Symbols
T11; SRBC; LFA-2
NCBI Protein Information
T-cell surface antigen CD2; CD2 antigen (p50), sheep red blood cell receptor; LFA-3 receptor; T-cell surface antigen T11/Leu-5; erythrocyte receptor; lymphocyte-function antigen-2; rosette receptor
UniProt Protein Name
T-cell surface antigen CD2
UniProt Gene Name
CD2
UniProt Synonym Gene Names
SRBC
UniProt Entry Name
CD2_HUMAN
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Product Notes
The CD2 cd2 (Catalog #AAA162989) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CD2 Rabbit anti-Human Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CD2 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the CD2 cd2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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